Not exact matches
Isoflavones seem to have the strongest oestrogenic effect, and are converted by bacterial fermentation into a
metabolite known
as equol (so named because it was first discovered in mare's
urine, in 1932).
HHMI investigator Arul Chinnaiyan and colleagues at the University of Michigan showed that
as prostate cancer develops and progresses, sarcosine levels increase in both tumor cells and
urine samples, suggesting that measurements of the
metabolite could aid in non-invasively diagnosing the disease.
As discussed in Part II of this review, urine hormone testing using both gas chromatography - mass spectrometry (GS - MS) or liquid chromatography - tandem mass spectrometry (LC - MS / MS) is well - established in the medical literature as a reliable method of assessing levels of active (free & conjugated) hormones and their metabolites, correlates well with patient symptoms, and reflects the beneficial impact (or lack of benefit and potentially oncogenic effect) of therapeutic interventions.43, 444 Radioimmunoassay (RIA) and enzyme - linked immunosorbent assay (ELISA, also known as enzyme immunoassay [EIA]-RRB- analysis may not be accurat
As discussed in Part II of this review,
urine hormone testing using both gas chromatography - mass spectrometry (GS - MS) or liquid chromatography - tandem mass spectrometry (LC - MS / MS) is well - established in the medical literature
as a reliable method of assessing levels of active (free & conjugated) hormones and their metabolites, correlates well with patient symptoms, and reflects the beneficial impact (or lack of benefit and potentially oncogenic effect) of therapeutic interventions.43, 444 Radioimmunoassay (RIA) and enzyme - linked immunosorbent assay (ELISA, also known as enzyme immunoassay [EIA]-RRB- analysis may not be accurat
as a reliable method of assessing levels of active (free & conjugated) hormones and their
metabolites, correlates well with patient symptoms, and reflects the beneficial impact (or lack of benefit and potentially oncogenic effect) of therapeutic interventions.43, 444 Radioimmunoassay (RIA) and enzyme - linked immunosorbent assay (ELISA, also known
as enzyme immunoassay [EIA]-RRB- analysis may not be accurat
as enzyme immunoassay [EIA]-RRB- analysis may not be accurate.
Etiocholanolone: One of two DHEA
metabolites reported on the 24 - Hour
Urine Test, etiocholanolone,
as noted above, has cancer - preventive anti-proliferative effects via its inhibition of G6PD.
Originated 1970s by Dr. Henry Lemon, who tested estrogen levels in 24 hour
urine samples and found that an EQ > 1 strongly correlated with a higher survival rate after breast cancer.24 Further research conducted by Lemon, Heidel, et al., a meta - analysis of published fractional estrogen excretion collected from 2,846 healthy women worldwide aged 15 to 59 years, with a risk of breast cancer varying five-fold, found that an EQ < 1 reflects increased rates of oxidation of estrone or estradiol to 4 - OH catechols (also referred to in the literature
as the 3,4 - catechol estrogen quinones), which have been identified
as the principal proximal human mammary carcinogens after menarche, while an EQ > 1 reflects conversion to protective 2 - OH estrogen
metabolites.2526
The SFN - NAC is not the only
metabolite present in
urine and,
as along with DIM, could be used
as biomarker of the consumption of cruciferous vegetables.
It was found that after only 7 days of tart cherry juice supplementation, there was an increase in the body's own melatonin production
as measured through
urine metabolites.