This protease activates hepatocyte growth factor (HGF) and
urokinase plasminogen activator (uPA), two proteins thought to be involved in the growth and motility of cancer cells, particularly carcinomas, and in the vascularization of tumors.
Everyone has
urokinase plasminogen activator receptor (uPAR), a healthy molecule «tethered» in place to various types of cells.
Not exact matches
Thrombosis recanalization by paeoniflorin through the upregulation of
urokinase - type
plasminogen activator via the MAPK signaling pathway.
A specific
plasminogen activator inhibitor - 1 antagonist derived from inactivated
urokinase.
Urokinase - type
plasminogen activator receptor regulates a novel pathway of fibronectin matrix assembly requiring Src - dependent transactivation of epidermal growth factor receptor.
They include its effects on endothelial cell «differentiation» to yield tubular - like structures, endothelial and tumor cell proliferation, apoptosis, and migration, as well as its effects on extracellular matrix remodelling enzyme activities of matrix metalloproteinase - 2 (MMP - 2) and
urokinase - type
plasminogen activator (uPA).