The NIH team evaluated the first family under an ongoing clinical protocol investigating
urticarias induced by a physical trigger.
«This work marks, to the best of our knowledge, the first identification of a genetic basis for a mast - cell - mediated
urticaria induced by a mechanical stimulus,» said Dean Metcalfe, M.D., chief of NIAID's Laboratory of Allergic Diseases and a study co-author.
Not exact matches
Scientists at the National Institutes of Health (NIH) have identified a genetic mutation responsible for a rare form of inherited hives
induced by vibration, also known as vibratory
urticaria.
To assess potential mast cell involvement in vibratory
urticaria, the researchers measured blood levels of histamine during an episode of vibration -
induced hives.
279/5: 30 Vibration -
induced urticaria due to aberrant mast cell degranulation caused by a mutation in ADGRE2.