Sentences with phrase «use bone marrow transplants»

In the new study, Ildstad and colleagues built on earlier attempts to use bone marrow transplants to help people receiving a new kidney.
The disease was reversed in a Canadian woman using a bone marrow transplant involving stem cells.

Not exact matches

A new study explains how a widely used drug is effective against inflammatory bowel disease and rejection of bone marrow transplants, while suggesting another way to address both health issues.
Richard Jones, M.D., professor and director of the Bone Marrow Transplant Program at Johns Hopkins, developed a now commonly used assay to study ALDH levels in individual cells.
A drug used to stop immune cells from gobbling up transplanted organs and bone marrow has been caught boosting the immune response to a virus in mice and monkeys.
In the early 2000s, Johns Hopkins scientists Leo Luznik and Ephraim Fuchs found that giving patients high doses of cyclophosphamide — a drug derived from nitrogen mustard and used to treat blood cancers — three days after bone marrow transplant successfully thwarts acute and chronic GVHD.
Medical centers around the world now use the Johns Hopkins protocol of post-transplant cyclophosphamide, and Luznik says the inexpensive drug is becoming increasingly mainstream in bone marrow transplant regimens.
It is similar to how radiation and chemotherapy are used to «condition» patients for a bone marrow transplant, to improve engraftment of transplanted immune cells.
The scientists began to use post-transplant cyclophosphamide in clinical trials of fully matched bone marrow transplants in 2004.
«New approach could make bone marrow transplants safer: Using antibodies in place of radiation, chemotherapy.»
Johns Hopkins Kimmel Cancer Center scientists first used cyclophosphamide to prevent severe graft - versus - host disease (GVHD) after bone marrow transplant involving haploidentical or «half - matched» transplants, a treatment first used in 2000 at the Cancer Center to treat leukemias and other blood cancers.
(Mackenzie notes that it shouldn't be a problem for her strategy, because she plans to use the same kind of cells as bone marrow transplants, which haven't caused tumors.)
Beyond organ transplants, many experts think that the protocol could be used to treat other diseases that require bone marrow transplants but for which there are severe shortages of matched donors.
These so - called hematopoietic stem cells (from Greek meaning «to make blood») have been reliably used over the past 40 years to seed bone marrow transplants in the treatment of some cancers and immune disorders.
Adult stem cell treatments have been used for many years to treat successfully leukemia and related bone / blood cancers through bone marrow transplants.
Capecchi warns that bone marrow transplants are too risky to be commonly used against, for example, OCD.
His Hutch team found that leukemia patients who received bone marrow transplants from an identical twin had far higher relapse rates than people who used a closely matched, but not identical, sibling.
However, a new study published in Cell Reports provides clues about how the dose of transplanted bone marrow might affect patients undergoing this risky procedure, frequently used to treat cancer and blood diseases.
Despite the grim prognosis, the Hutchinson center offered to do a second transplant using his half brother Michael's bone marrow.
Using stem cells harvested from human bone marrow, researchers transplanted cells into mice modeling ALS and already showing disease symptoms.
The authors write that PBSCs are still used, despite disadvantages in patients with bone marrow failure, most likely because centers obtain PBSCs routinely for other indications and cell separators are available at any transplant center.
(Bone marrow transplants use adult stem cells, a treatment that has been used for decades.)
The Bone Marrow and Stem Cell Transplant Program is expanding the use of this technique for patients with solid tumors including neuroblastoma and brain tumors; a variety of high - risk hematologic diseases, such as thalassemia major and transfusion - dependent sickle cell disease; and other nonmalignant diseases.
A number of adult stem cell therapies already exist, particularly bone marrow transplants that are used to treat leukemia.
Through this development, the Cancer Center can offer potentially curative bone marrow transplants to an increasing number of patients by using alternative bone marrow donors.
The South Florida Bone Marrow / Stem Cell Transplant Institute is now running a new clinical trial protocol (08001 - BMSCTI) for investigating a novel cancer therapy using transfusions of white blood cells from healthy donors.
This involved a bone marrow transplant, which he underwent as part of treatment for leukaemia, using a donor with a rare genetic mutation rendering their cells resistant to HIV.
This is why transplants of HSCs (from bone marrow) are also used to treat cancers of the hematopoietic (blood) system, such as leukemia or lymphoma.
The first stem - cell - based therapy was a bone marrow transplant used to treat leukemia.
And so this might be used, let's say, in a transplantation setting, similar to a bone marrow transplant.
Radiation is often used in conjunction with other cancer treatments such as surgery, chemotherapy or bone marrow transplant, depending on each child's specific diagnosis.
The ability to safely use half - matching donors (parents, most siblings, and all children of the patient) makes bone marrow transplant an effective option for the majority of sickle cell patients.
Our expertise includes both autologous and allogeneic stem cell transplants (using cells directly from the patient and from another person, respectively), using cells derived from bone marrow, peripheral blood and cord blood.
These advances make it possible for half - identical bone marrow transplants to be used in nonmalignant diseases, such as aplastic anemia, lupus, and sickle cell anemia.
Hyperimmune bovine colostrum has been used in clinical trials for treating AIDS - related diarrhea, diarrhea associated with graft versus host disease following bone marrow transplant, and rotavirus diarrhea in children.
One type of stem cell transplant, autologous hematopoietic stem cell transplantation, uses stems cells from your own bone marrow, or from external umbilical cord blood.
It is also used after bone marrow transplants and bowel surgery to improve recovery, prevent infection, and increase well - being.
At least four are at various stages of development and use: The technology for bone marrow transplants has been around for more than 20 years.
Vigani partners with Steven Suter, associate professor of medical oncology and director of the VH's Canine Bone Marrow Transplant Unit, to perform plasmapheresis using the same machine used for bone marrow transplaBone Marrow Transplant Unit, to perform plasmapheresis using the same machine used for bone marrow transpMarrow Transplant Unit, to perform plasmapheresis using the same machine used for bone marrow transplabone marrow transpmarrow transplants.
Bone marrow transplants for dogs is a relatively new procedure that involves the use of Leukophoresis machines — the same equipment used in human medicine — that are designed to harvest healthy stem cells from the peripheral blood.
Under minimal supervision, the Bone Marrow Transplant Program Administrative Director uses advanced clinical program...
This subset of scales from the FES and their composite score has been used with families of children with asthma, diabetes, juvenile rheumatoid arthritis, recurrent abdominal pain, sickle cell disease, and those undergoing bone marrow transplant (BMT).
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