Sentences with phrase «use cyclodextrins»

My group is also working on A2E lipofuscin in the retina, and we've managed to remove it with a different treatment (using cyclodextrins).

Not exact matches

Now Fraser Stoddart of Northwestern University in Evanston, Illinois, and colleagues have devised a cage made of gamma - cyclodextrin, a ring of glucose molecules often used as a food additive (Angewandte Chemie, DOI: 10.1002 / anie.201002343).

Cyclodextrins have been used to deliver drugs because they can trap complex hydrophobic (greasy) molecules in their hydrophobic cavity.

D'Souza's team used an efficient reaction to make the intermediate, heptakis -2,3-epoxy-beta-cyclodextrin, from a known silicon - containing derivative of beta - cyclodextrin (Journal of the Chemical Society, Chemical Communications, 1992, p 1112).

Doughnut - shaped cyclodextrin molecules used as catalysts, enzyme mimics, drug carriers and food stabilisers, have been studied for more than a decade.

(One of Hempel's daughters suffered a stroke after ICV administration of cyclodextrin, although not as part of the NIH trial; it was being administered separately under a compassionate use protocol approved by the Food and Drug Administration.)

The Johns Hopkins team used a microshell made of a sugar - based polymer called cyclodextrin to protect the 3BrPA drug molecules from disintegrating early and to guard healthy tissue from the drug's toxic effects, such as weight loss, hypothermia and lethal hypoglycemic shock.

Cyclodextrin is a sugar molecule that long has been used as a minor ingredient in many other pharmaceuticals because it helps drug compounds dissolve in water.

Chan emailed the twins» mother, who told him what to do to get Galya on the treatment, and then asked Wang if he'd be willing to apply on his daughter's behalf for compassionate use of cyclodextrin.

The Wikipedia page also linked to stories about twin 5 - year - old girls who in 2009 had become the first Americans to fight NPC with an experimental treatment called cyclodextrin — but only after their parents had spent years pressing for «compassionate use» of the investigational drug outside of a clinical trial.

The reason alpha - cyclodextrins lower postprandial glucose and cholesterol, and the reason they got relatively easy approval for use as food additives even in the EU, is because they aren't absorbed systemically: they work largely as soluble fiber does, binding excreted bile acids and slowing absorption of glucose.

α - Cyclodextrin has been authorized for use as a dietary fiber in the European Union since 2008.

Because cyclodextrin treatment in humans is safe (FDA approved application of 2 hydroxypropyl - β - cyclodextrin for the treatment of Niemann - Pick disease, type C. Phase I clinical trial) and cyclodextrin beneficially affects key mechanisms of atherogenesis, it may therefore be used clinically to prevent or treat human atherosclerosis http://stm.sciencemag.org/content/8/333/333ra50.