Sentences with phrase «use in clinical trials»

Work is currently underway to certify spider silk as a medical device, so that it can also be used in clinical trials on humans.

Decitabine is approved by the U.S. Food and Drug Administration to treat myelodysplastic syndromes and leukemia, and for use in clinical trials for several types of solid - tumour cancers including colorectal.

Such drugs are currently used in clinical trials for certain types of cancer and are standard therapy for a type of pre-leukemia condition.

While placebos have been used to ease pain and other symptoms for centuries and are used in clinical trials as controls for testing new drug therapies, the biology underlying placebo effects has only recently been truly appreciated.

Co-authors of the paper work at the University of California San Francisco where the phantom is already used in clinical trials.

Here is a chart of average curcumin doses used in these clinical trials.

An advantage of small - molecule PPF — which has been previously used in clinical trials in an attempt to treat Alzheimer's disease and dementia — is that it can penetrate the blood - brain barrier and reach the tumor.

«Progressive disease» is a new provisional response category to be used in clinical trials only; the purpose of the category is to harmonize the various definitions of progressive disease that are used in different clinical trials.

Common bias safeguards used in clinical trials not always followed in animal research, study suggests

For this reason, health authorities require that new infant formulas be tested in piglets before they can be used in clinical trials of human babies.

«Efficacy» is used in clinical trial settings, whereas «effectiveness» is used in real world (not carefully controlled) settings.

Asterias has banks of these embryonic stem cells, derived from this cell line, which the company can multiply to make cells as needed and, in turn, convert them into oligodendrocyte progenitor cells for use in clinical trial evaluation in patients.

They have been used in clinical trials since the mid-1990s treating hundreds of subjects with currently no known related serious adverse events.

Antagonist compounds that can pharmacologically block FKBP51 have been developed at Max Planck, and the researchers say they're currently improving on them for eventual use in clinical trials.

The SMA Foundation and RBM are continuing to analyze these results and plan to create a specific panel of biomarker assays for use in clinical trials exploring new treatments for SMA.

I started taking 6g daily of hydrolyzed collagen appx 6wks ago (the amt used in clinical trials for improving aging skin and hydration).

The specific methods of behavioral modification used in clinical trials involved desensitization and counterconditioning techniques.

We used these to repaper contracts for six of the world's largest banks as part of uncleared margin reform, and also currently use them in our Clinical Trial Agreement and M&A solutions.

The important property of these mutations targeting Phe958 and Pro960 is that they not only make the kinase constitutively active, but also give increased resistance to ATP - competitive inhibitors, including INCB018424, which is currently used in clinical trials for JAK2 V617F - positive MPNs.12

A research team led by Gianluca Maddalo (KTH), involving several researchers at SciLifeLab, has discovered that melanoma resistance against BRAF and Hsp90 inhibitors can be overcome by implementing the current BRAF / MEK inhibitors therapy with a CDK2 inhibitor, dinaciclib, already used in clinical trials.

«Our compound is very specific for the target, and we do not see any side effects after treatment in mice for a month, but the next step is to rigorously establish if it's safe for use in clinical trials,» says Stanford.

Deals with pharmaceutical makers to package the Biojector 2000 with specific drugs — including those being used in clinical trials — give it a clear advantage over some competing devices, says Bioject CEO Jim O'Shea.

Brendan Kennedy, the cofounder of Privateer Holdings, which owns various marijuana companies like Marley Natural and Canadian pharmaceutical - grade cannabis producer Tilray, explains how Tilray is already exporting marijuana to countries like Croatia and Australia for use in clinical trials.

However a lesser known berry — the gooseberry — has now been used in clinical trials to prove its reduction in cardiovascular diseases.

People working in biomanufacturing need to be prepared for inspections by the US Food and Drug Administration and the European Medical Evaluation Agency designed to ensure that mass - produced proteins are of the same quality as those used in clinical trials.

The Institute of Medicine, meanwhile, is holding a series of meetings to discuss how technologies like these are used in clinical trials.

But bryostatin 1 was important to make because it's the only version of the molecule that has been used in clinical trials, Wender says.

He launched the study when he discovered heart attack patients were being treated with much lower doses of beta - blockers than were used in clinical trials.

«We set out on a mission to show if you treat patients with the doses that were used in the clinical trials, they will do better.

Instead of simply tracking what the outlets were publishing and analyzing their impact on public opinion, the researchers took an approach similar to that used in clinical trials to evaluate the effects of new drugs.

The Institute of Medicine (IOM) report says that so - called «omics» tests — diagnostic tools based on molecular patterns — are highly prone to errors; it recommends they be rigorously validated before being used in clinical trials.

The next step for ovarian cancer research would be to develop a drug for human consumption that could be used in clinical trials.

Many of them have already been used in clinical trials.

Dr. Baraban's group is currently developing clemizole and its derivatives, for use in clinical trials.

It costs millions of dollars to develop drugs and get them tested in animals before they can ever be used in clinical trials for safety and efficacy in humans.

It bars a researcher from receiving drugs for use in clinical trials — in effect, preventing that investigator from administering experimental drugs to patients.

«As a basic scientist, it is exciting to be able to translate a laboratory discovery into drugs that are now being used in a clinical trial.»

They gave mice a drug — AICAR, which has been used in clinical trials for various diseases — that upped AMP - activated protein kinase (AMPK), an enzyme that becomes activated during a workout.

Her expertise includes optimization of standard operating procedures for cGMP manufacture of transgenic T cells, stem cells and dendritic cells to be used in clinical trials, planning and writing clinical trial protocols, IND (investigational new drug) applications and other regulatory documents.

Thermal proteome profiling (TPP) identified the protein targets of the Hsp90 inhibitor XL888 (currently used in clinical trials) in a pair of sensitive and unresponsive cell lines.

As we'll see later on, this has already contributed to their receiving FDA - approval for use in a clinical trial.

The goal is to create a set of measures that can be used in clinical trials to determine which treatments are best for which patients and who will benefit from a particular treatment.

All PET / CT scanners (or by special exception, PET - only scanners) that are planned for use in clinical trials must undergo this validation process by successfully completing the defined steps outlined in the Scanner Validation Committee SOPs.

In addition to the above, Dr. Matsuzaki has been conducting preclinical assessment of drug efficacy such as IDO inhibitor, rapamycin or decitabine that have been used in clinical trials.