Sentences with phrase «use of activation»

You can integrate some of those devices via IFTTT, Yonomi, or a smart - home hub, but native control is faster and more reliable, and it requires a less awkward use of activation phrases.

In experiments using enzyme inhibitors, the possibility that cinnamtannin B - 1 enhanced mobilization through the use of activation of enzymes such as PI3 kinase near the cell membrane was shown.

Not exact matches

JCAR017 uses a defined CD4: CD8 cell composition and 4 - 1BB as the co-stimulatory signaling domain to mimic a «second signal» that amplifies the activation of CAR T cells, which according to Juno leads to a more robust signal to the T cell to multiply and kill the cancer cell.

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The link between depression and the immune system has been shown using positron emission tomography using a tracer for the translocator protein (TSPO) showing increased immune activation in the brains of patients with major depressive disorder compared with control subjects.

These «two poles» involve respectively the «presupposition of] the mathematical structure of matter, its intrinsic rationality, which makes it possible to understand how matter works and use it efficiently», which wonderfully «correspond ^ with] our spirit», and our own experimental activation of «nature's capacity to be exploited for our purposes».

Gold award winners included: Brazil's Froneri for a cardboard ice cream cup featuring a PP in - mold label, closure with spoon inside and aluminum / PE sealing; and Insignia Technologies for its Freshtag shelf - life indicator tag designed to change color over a pre-set number of days at a prescribed temperature, while the color change is faster when the temperature increases; and PPi Technologies for MosquitoPaQ, which uses a frangible sealed pouch that allows consumers to mix and activate the dry and wet chemicals at the time of use, without having to pour out or touch the contents; after activation, consumers hang the pouch nearby and leave it alone as the repellent is released over the course of 15 days.

We have previously described studies of pacing strategy using various experimental interventions, including faster and slower starts, higher temperatures, hypoxia, hyperoxia and altered energy substrate availability.1 We have proposed the presence of a complex, regulatory system that mediates changes to skeletal muscle motor unit activation and work rate in order both to optimise performance and prevent potentially harmful changes to homeostasis.

I have been a fan of Rapidlash for over 6 years but haven't used it consistently until I was asked to as part of a Influencer Activation on behalf of Influence Central for RapidLash.

Campaigns use the Voter Activation Network to access voter rolls and obtain the names, addresses, ages and party affiliations of registered voters — particularly useful for get - out - the - vote ground operations like the one ABQ ran.

During the meeting, Borough President Katz also noted the one year anniversary of the Jamaica NOW Action Plan's April 15, 2015 launch and outlined major milestones of the Jamaica NOW Action Plan in the past year, including the activation of the Bronx - Flushing - Jamaica Q44 Select Bus Service that serves 44,000 New Yorkers daily; the newly - restored paths at Rufus King Park that are part of the first phase of the Park's major capital improvements; redesigned storefronts of local businesses along Sutphin Boulevard (with more on the way); a $ 138,000 «Building Community Capacity» grant toward the formation of the Jamaica Arts Alliance; the release of an RFP to activate the 168th Street Garage into a new, mixed - use development, with the City to announce the winning bid shortly; the launch of the «Jamaica Avenue Streetscape Improvements» study to determine the cost and scope of additional seating, increased plantings and improved pedestrian circulation in the area; and free public Wi - Fi on track by July in the Downtown Jamaica Corridor, the first area in Queens to host LinkNYC.

Though our feelings may seem unique, our brains process them using a similar pattern of neuron activation.

A new study in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging using magnetic resonance imaging (MRI) reports a link between reduced functional activation and reduced cortical thickness in the brains of patients with bipolar disorder.

In June, neuroscientist Adam Anderson's team at Cornell University demonstrated that, though our feelings may seem unique, our brains process them using a similar pattern of brain cell, or neuron, activation — meaning we feel feelings the same way.

«In contrast to RNA interference, which is commonly used to inactivate gene activity, the CRISPR - on system allows activation of cellular genes.

Functional brain - imaging experiments done at the end of the past century using positron - emission tomography (PET) found marked activation in the frontal lobe of volunteers who had taken hallucinogens, in particular in the prefrontal cortex (PFC), anterior cingulate cortex (ACC) and the insula cortex.

If the tail is bound and made inaccessible using a further antibody, activation of the switch can likewise no longer trigger cell death.

Óscar Llorca and his team have used this technique to learn about the structure and functioning of a complex system called R2TP, which is involved in various key processes for cell survival such as the activation of the kinases mTOR, ATR and ATM, proteins that are the target of various cancer drugs currently being developed.

«By using various approaches, we validated that NOX1 and NOX4 have a key mediation role in liver fibrosis, including the direct activation of HSCs,» said Brenner.

Alternatively, a combination of treatments might work, Hunt says, possibly using a probiotic to modulate the gut microbiome, and an anti-inflammatory drug to dampen the immune response and problems associated with immune activation.

Using the nanodiscs, the team elucidated the activation mechanism of receptor kinase AgrC and discovered a key regulatory hotspot in the kinase that could greatly affect its activity.

The researchers used valproic acid which can induce the activation of such deactivated genes in fungi.

The engineers were able to work around the hydrogen storage problem by using non-polluting Proton Exchange Membrane (PEM) fuel cells and a process of aluminum activation patented by the paper's co-authors, Prof. Alon Gany and Dr. Valery Rosenband.

Using multiple opsins as well as blue, yellow, and green light, he can experiment with various combinations of activation in hopes of eliminating symptoms of disease.

To investigate the direct impact of VTA activation on primate behavior, the research team used high - resolution magnetic resonance imaging to guide the placement of microelectrodes within the VTAs of macaque monkeys.

The researchers advise that these three gold standards should be used in future in research on new medicines that rely on the activation of the cannabinoid CB2 receptor for their effectiveness.

The researchers also found that activation of ESP1 - responding neurons in the region of the brain called the hypothalamus enhanced sexual behavior in female mice, even in the absence of actual ESP1, by using various tools to chemically or optically control neural activities, combined with a process called the TRAP method, which allows them to selectively manipulate neurons responding to a particular stimulus.

By using pharmacological small molecule inhibitors as well as neutrophils from genetically modified mouse strains the team could identify essential receptor and signaling pathways involved in the nicotine - mediated activation of neutrophils.

The team recently received an internal campus grant to use the method to control gene activation in specific regions of the brain.

In the future, the scientists plan to use this system to study the effect of these and other compounds that may prevent the activation of HIV - 1 in the brain.

«Combination therapies using BRAF inhibitors and other inhibitors are being considered to prevent paradoxical activation of MAPK pathways.»

But her most important achievement, she thinks, was shedding new light on the physiology of brain activation by using a variety of different contrast agents.

In a follow - on project to be conducted in collaboration with MedUni Vienna's Institute of Pharmacology and Center for Addiction Research and Science (AddRess) and, in particular, with drug and dopamine expert Harald Sitte, amongst others, the objective is now to find out whether, and, if so, how, activation of DeltaFosB can be prevented and how this highly promising starting point can be used to treat the onset of addictive behaviour.

Rutgers University scientists have discovered the three - dimensional structure of a gene - specific transcription activation complex, providing the first structural and mechanistic description of the process cells use to turn on, or activate, specific genes in response to changes in cell type, developmental state and environment.

Even more dubious is the practice of using TOF values to derive activation energies.

One aspect of the EPM operation that makes them really useful is that using lower activation currents, weaker magnetic fields can be obtained.

Lengner cautions, however, that rapamycin can not be used as a stand - in for calorie restriction, as it would linger and continue to block mTOR activation even following injury, hindering the ability of the reserve stem cells to spring into action and regenerate intestinal tissue.

Using gene therapy to insert the gene, they expressed the synthetic gene in adult mice or in zebrafish embryos, and witnessed remote activation of neurons the presence of a magnetic field through the altered behavior of the animals.

NIRSIT allows the researchers to monitor the subject's brain activation changes and analyze the results in an intuitive way, using both the 3D brain mapping images as well as the oxy - deoxy graphs covering the prefrontal area of the brain.

The brain regions they used to make those choices were also different: for individuals with anorexia nervosa, choices about what to eat were associated with activation in the dorsal striatum, a brain region known to be related to habitual control of actions.

Dr. Britt obtained these results using optogenetics, which use light - responsive proteins to study the activation of neural circuits in distinct locations, allowing the researcher to precisely dissect the roles of different neural circuits in the brain.

The team of researchers tracked when participants first activated their activity tracker, how frequently the device was used in the first six months following activation, average daily step counts and sociodemographic characteristics.

Between - group analysis of phase 2 demonstrated a significant activation cluster in the ipsilateral posterior insula (pIns) in group P. Using the pIns as a seed region the PPI analysis yielded a significant enhanced coupling to the midbrain (periaqueductal grey / ventral tegmental area) after analgesia onset in group A only.

A group of researchers at the University of Wisconsin, overseen by J. Wesley Pike, have now overcome this hurdle by using CRISPR / Cas engineering to produce mice with kidney - specific control of vitamin D activation.

Using an imaging procedure with high resolutions, the scientists revealed that a simultaneous counterchange of luminance of neighboring stimuli creates a sequential activation in the primary visual cortex.

But using sophisticated mathematics, scientists discerned a pattern of cortical activation and deactivation, cycling every five to ten minutes — this, the scientists note, is a crude precursor to the longer cycles of REM and non-REM sleep.

«Using statistical methods, we were able to identify a small number of basic patterns that underlie muscle activities in the legs and control periodic activation or deactivation of muscles to produce cyclical movements, such as those associated with walking.

For the first time ever, the study used this formation of novel enhancer regions to describe the selection of enhancers and the progression of the activation from transcription factor binding to histone acetylation and eRNA transcription, finally leading to the mono - and dimethylation of histone H3 lysine 4 (H3K4me1 / 2).

By tweaking the locations and identities of motor neurons, and then watching the resulting patterns of activation using their new fluorescent technique, Chris Hinckley in the Pfaff laboratory found that the CPG didn't rely solely on the cells» locations to connect to them.

To find out whether ejaculation produced an immediate pleasurable response, the researchers used an arena in which one side emitted a red light to trigger optogenetic activation of CRZ neurons and tracked where male flies chose to spend their time.