Sentences with phrase «use of an animal drug»

Not exact matches

Resistance is also fueled by the massive and often inappropriate use of antibiotics in agriculture; for decades these precious drugs have been used to promote growth and fend off costly infections that can result from the cramped conditions of industrial - scale food animal production.

Such concern has sparked the launch of the Obama administration's five - year plan to combat antibiotic resistance, as well as the Food and Drug Administration's new guidelines aiming to restrict antibiotic use in farm animal products, like meat and poultry, that make it to our dinner plates.

More sophisticated use of GM plants and animals to produce human medicines — dubbed «pharming» — is a new field which promises to deliver drugs too complex to be synthesised in the test tube.

In view of this it should avoid the use of fertilizers, pesticides, animal drugs and food additives that may have adverse health effects.

In a 1992 article in The North American Review entitled «The Corruption of Nobility: The Rise & Fall of Thoroughbred Racing in America,» Ferraro penned a stinging rebuke against drug abuse on the backstretch, saying, «In general, treatments designed to repair a horse's injuries and to alleviate its suffering are now often used to get the animal out onto the track to compete — to force the animal, like some punch - drunk fighter, to make just one more round.

Here are some of the excluding criteria most experts agree on: «Obese parents; parents who smoke (either during pregnancy or at present); parents sleeping on a waterbed, recliner, sofa, armchair, couch or bean bag; parents who sleep on multiple pillows, a sagging mattress or a sheepskin or use heavy bedding, such as comforters or duvets; sleeping in overheated rooms; parents under the influence of drugs or alcohol; other children or pets who can or are likely to climb into the bed; and stuffed animals on the bed that could cover the baby's face.»

The Food and Drug Administration has long permitted its use, but in recent years concerns about the chemical have grown as studies have indicated low doses of the substance can disrupt hormone systems in laboratory animals and possibly increase the risk of cancer or other serious illness.

And while the science may be disputed, depending on who is funding the study, as to whether commonly used food dyes such as Yellow 5, Red 40 and 6 others made from petroleum pose a «rainbow of risks» that include hyperactivity in children, cancer (in animal studies), and allergic reactions, because of the problem of hyperactivity, the Center for Science in the Public Interest petitioned the Food and Drug Administration to ban the use of these dyes given that the British government and European Unionhave taken actions that are virtually ending their use of dyes throughout Europe.

Although hormonal growth promoters are illegal in the UK, it is widely feared that the use of antibiotics may be contributing towards the development of drug - resistant bacteria, with potentially serious consequences for animal and human health.

Studies show that these models can accurately predict the ways that new drugs will react in the human body and replace the use of animals in exploratory research and many standard drug tests.

Congresswoman Louise Slaughter, «Confirmed: 80 percent of all antibacterial drugs used on animals, endangering human health,» Feb. 23, 2011

«Autism's social deficits are reversed by an anti-cancer drug: Using an epigenetic mechanism, romidepsin restored gene expression and alleviated social deficits in animal models of autism.»

Because Nanotax is a repurposed form of an already in - use drug, it shortened the time between animal and patient trials.

FOR the first time, an HIV - like infection has been cleared from an animal without the use of antiviral drugs.

BPTES has been used in animal models for a variety of cancers but has not substantially reduced tumor sizes, probably because the drug concentration in tumor tissue is not high enough when using conventional drug formulation methods, say the scientists.

Furthermore, there are no differences between the major political party affiliation groups on views about the use of animals in research, the safety of eating genetically modified (GM) foods and whether to allow access to experimental drug treatments before those treatments have been shown to be safe and effective.

Why the drug combination works in resistant CML Why such a combination of the two inhibitor types works in an animal model has now been explained by Prof. Stephan Grzesiek's team at the Biozentrum of the University of Basel and Dr. Wolfgang Jahnke from Novartis, by a structural analysis using nuclear magnetic resonance spectroscopy (NMR).

Psychiatric drugs are also used in birds, though animal welfare groups worried that the use of such drugs to treat behavioural problems in animals would create a population of «pill - popping pets».

Now, the researchers have discovered an alternative in a mouse model: in the case of breast tumours with a specific defect in DNA repair, the animals can be cured using already established, cheap chemotherapy drugs, if enough DNA damage can be inflicted on the resting tumour cells.

The presence of antibiotics within the food chain is likely to increase as the U.S. Food and Drug Administration has permitted greater use of controversial drugs on farm animals.

The researchers found that as the animals self - administered more MDPV per session, their use of the wheel declined significantly, indicating that the drug had made this normally rewarding behavior seem much less appealing.

(Update, 9:26 pm Statement from New Iberia:» Nothing in the videos alter the fact that the New Iberia Research Center is in compliance with all federal standards and guidelines regarding the care and use of animals, as determined by the U.S. Department of Agriculture, the Food and Drug Administration, and the Centers for Disease Control.»)

In animal and cell culture studies, the drug inhibited growth both in estrogen - dependent breast cancer cells and in cells that had developed resistance to the anti-estrogen tamoxifen and / or to the aromatase inhibitors, two of the most widely used types of drugs to prevent and treat estrogen - dependent breast cancer.

Importantly, these devices also will open up new approaches to drug development not possible with animal models today, such as personalized medicines and development of therapeutics for specific genetic subpopulations using chips created using cells from particular patients.»

«Maybe at the one - cell or two - cell stage,» Eggan and his colleagues reasoned, «there's still some of that stuff in there...» And if they picked the right moment of cell division, when these powerful reprogramming factors were still floating around in the periphery of the cell, they might be able to use drugs to temporarily freeze the cell in the middle of division, stick in the needle of a micromanipulator to suck out the embryonic DNA, squirt in DNA from an adult animal, and then kick - start the process of reprogramming — hours, perhaps even days after an egg had been fertilized.

In a novel animal study design that mimicked human clinical trials, researchers at University of California, San Diego School of Medicine report that long - term treatment using a small molecule drug that reduces activity of the brain's stress circuitry significantly reduces Alzheimer's disease (AD) neuropathology and prevents onset of cognitive impairment in a mouse model of the neurodegenerative condition.

In their report that has received advance online publication in Nature Nanotechnology, a research team based at the Wellman Center for Photomedicine at Massachusetts General Hospital (MGH) describes how a nanomedicine that combines photodynamic therapy — the use of light to trigger a chemical reaction — with a molecular therapy drug targeted against common treatment resistance pathways reduced a thousand-fold the dosage of the molecular therapy drug required to suppress tumor progression and metastatic outgrowth in an animal model.

Regardless of whether Landrigan's legal team was simply using the drug shortage as stalling tactic, their legal maneuvering brings to the fore a contentious dispute over the science (or some would say lack thereof) behind lethal injection executions in the U.S.. For more than two decades, it has been argued that the FDA should be required to certify the safety and effectiveness of drugs used to carry out executions (as it does for drugs used to euthanize animals).

In the study, Bruce Hope, from the National Institutes of Health National Institute on Drug Abuse Intramural Research Program in Baltimore, Maryland, and colleagues used animal models to investigate if the brain forms drug - related memories in a similar Drug Abuse Intramural Research Program in Baltimore, Maryland, and colleagues used animal models to investigate if the brain forms drug - related memories in a similar drug - related memories in a similar way.

For the current study, Jessica Childs, a graduate student in Kroener's lab, applied VNS to a test group of rats used in the study in a process called «extinction learning» to determine whether the procedure could help the animals learn different behaviors and reduce their drug cravings.

The pharmaceutical industry uses genetically modified bacteria and animals to produce insulin, vaccines, and a wide variety of drugs.

He added that the existence of episodic memory in lower animals has implications for research on human diseases that affect memory, including Alzheimer's, Parkinson's and Huntington's diseases, since the majority of research on the brain — and the drugs used to treat memory diseases and dementia — start out based on insights into how the brain works in rats.

The researchers examined respondents» deference to science on a scale of 0 - 10 when it came to 14 policy issues, including child vaccinations, stem cell research, global warming, child obesity and diet, AIDS prevention, birth control education, legalizing drug use, gun control, regulation of nuclear power, animal testing, and teaching evolution in schools.

The Italian law would ban in 2017 the use of animals to study drug abuse research and xenotransplantation.

«Importantly, we use mice as models of human beings in research, and so when looking for anti-obesity drugs, we need to fully understand the function of the NPY system in this animal model to understand how similar circuits in humans connect with the body clock.»

This has led to a demand for people who can understand data collection techniques and analyze vast amounts of data, categorize the data sets, develop models to test hypotheses that can then be used to develop drugs, and test potential candidates in animals.

«This work sets the stage for additional animal studies to see if tamoxifen can be used as a drug in people and will allow us to design new drugs related to tamoxifen that are better antifungals,» says Damian Krysan of the University of Rochester, an author on the study.

Both classes of drugs are used in animals and humans.

More animal studies would be needed to move this drug toward human clinical trials, but «what we hope is that we could use this drug to intervene in patients who have had an episode of prolonged seizures and give it to them briefly following that episode to protect them from becoming epileptic,» said James McNamara, M.D., a professor in the departments of neurobiology and neurology at Duke University.

The original aim of the treaty was to ensure that Third World nations would be rewarded if the plants and animals found within their borders were used in the development of new drugs.

By revealing skin sensitisation or an adverse reaction that may not be identified by use of an animal or computer model, the assay can provide vital information which will allow a drug company to make informed decisions earlier saving significant development costs.

CHICAGO (Reuters)-- The sale and distribution of antibiotics approved for use in food - producing animals in the United States decreased by 10 percent from 2015 to 2016, a U.S. Food and Drug Administration (FDA) report said on Thursday.

One particularly worrisome finding, to be published soon in the Journal of Zoo and Wildlife Medicine, is that treatments with voriconizole, an antifungal drug often used in animal care, sometimes kills even apparently healthy snakes.

Using these and other papers reporting the results of experiments on prototype smart drugs, I examined well over 100 studies, some on animals, some on people with dementia, some on healthy people.

dispersal of new drugs in animal studies, among other uses.

It costs millions of dollars to develop drugs and get them tested in animals before they can ever be used in clinical trials for safety and efficacy in humans.

To test the capsule's real - world applications, the team used both mathematical modeling and animal models to investigate the effects of delivering a sustained therapeutic dose of a drug called ivermectin, which is used to treat parasitic infections such as river blindness.

(Reuters)- The U.S Food and Drug Administration said it is asking drugmakers for data on antimicrobials sold for use in each food animal, such as cows and chickens, as part of efforts to combat antibiotic - resistant bacteria.

If the team used a drug to block the effects of dopamine, the neurotransmitter associated with feelings of enjoyment, the animals did not drink the salty water.

«We are exploring alternative directions for developing this compound, including potential use of the animal efficacy rule,» Cihlar said, referring to a regulatory mechanism under which the U.S. Food and Drug Administration may consider efficacy findings from adequate and well - controlled animal studies of a drug in cases where it is not feasible or ethical to conduct human triDrug Administration may consider efficacy findings from adequate and well - controlled animal studies of a drug in cases where it is not feasible or ethical to conduct human tridrug in cases where it is not feasible or ethical to conduct human trials.