Sentences with phrase «use of drugs which»

Not exact matches

Genmab's strategy is to use its growing royalty stream from Darzalex to invest in its next wave of medicines like cervical cancer drug tisotumab vedotin, which is being developed in a 50/50 partnership with Seattle Genetics.

Marino's draft stock had fallen after a disappointing senior season at Pitt, as well as rumors of recreational drug use, rumors which even led Marino's hometown team the Pittsburgh Steelers to pass on selecting him.

In a realm of swirling, incomprehensible big biological data — which is, perhaps, another way of thinking about the human body — the opportunity to use computer learning to better anticipate which drugs will work well (and not so well) in any one person is one we shouldn't pass up.

These risks and uncertainties include, among others: the unfavorable outcome of litigation, including so - called «Paragraph IV» litigation and other patent litigation, related to any of our products or products using our proprietary technologies, which may lead to competition from generic drug manufacturers; data from clinical trials may be interpreted by the FDA in different ways than we interpret it; the FDA may not agree with our regulatory approval strategies or components of our filings for our products, including our clinical trial designs, conduct and methodologies and, for ALKS 5461, evidence of efficacy and adequacy of bridging to buprenorphine; clinical development activities may not be completed on time or at all; the results of our clinical development activities may not be positive, or predictive of real - world results or of results in subsequent clinical trials; regulatory submissions may not occur or be submitted in a timely manner; the company and its licensees may not be able to continue to successfully commercialize their products; there may be a reduction in payment rate or reimbursement for the company's products or an increase in the company's financial obligations to governmental payers; the FDA or regulatory authorities outside the U.S. may make adverse decisions regarding the company's products; the company's products may prove difficult to manufacture, be precluded from commercialization by the proprietary rights of third parties, or have unintended side effects, adverse reactions or incidents of misuse; and those risks and uncertainties described under the heading «Risk Factors» in the company's most recent Annual Report on Form 10 - K and in subsequent filings made by the company with the U.S. Securities and Exchange Commission («SEC»), which are available on the SEC's website at www.sec.gov.

Using the drug as an anti-aging treatment makes sense, since it helps the body be more sensitive to insulin, which in turn lowers the amount of blood sugar in the body and helps things run more smoothly.

The Food and Drug Administration (FDA) is investigating patient deaths following an obesity - fighting procedure which involves the use of balloons that fill up inside the stomach and remain for about six months.

This is a far cry from the early days of the bitcoin craze, when the currency was largely linked with the now - shut down «Silk Road,» which was allegedly used to sell drugs and other illicit items.

Content in which someone «admits to personal use of non-medical drugs» should not be posted on Facebook, the rule book says.

The reason there's no generic Viagra yet is because Pfizer, the company that makes it, holds two patents for the drug: the first for Viagra's composition — which expired in 2012 — and the second for what's called a «method of treatment,» meaning how the drug is used.

Intarcia has completed several late - stage clinical trials in which it uses the pump to deliver a glucose - controlling drug continuously for months — an idea, that if successful (and approved by the FDA) could significantly help patients with type 2 diabetes, fewer than half of whom maintain the recommended glycemic levels.

The biotech plans to shed 20 % of its nearly 600 employees in order to secure yearly cost - savings of about $ 21 million — money which can then be used to double down on late - stage clinical trials for its experimental Parkinson's drug.

Marijuana's position in the top tier of the scheduling system — which organizes drugs by their «acceptable medical use and... abuse or dependency potential» — has endured since the 1970s.

Phase I funding — which allows up to $ 250,000 for an academic idea, such as decoding the genetic sequence of a protein or studying targeted drug delivery by using magnetic nanoparticles — is available from federal funding and foundations.

It's also unclear that the increased marijuana use by pregnant women represents drug abuse; for instance, nausea and anxiety (both common among pregnancy) are among the most common symptoms of medical marijuana users, which may in part explain the increase in usage.

That's a big deal because Alnylam's drug is based on an extremely early - stage kind of medical technology called RNAi, or RNA interference, which uses basic biological building blocks to tackle problematic genetic discrepancies.

Gorsuch's commitments to interpreting the law as «the words on the paper say» and not over-criminalizing innocent conduct were on full display in a 2015 decision in which he used «plain old grade school grammar» to determine the legal penalties imposed on defendants accused of using a firearm «during and in relation to any crime of violence of drug trafficking crime.»

On November 8, the US House of Representatives held a hearing on the effectiveness of a 1999 law known as the Kingpin Act, which is used to sanction individuals suspected of involvement in the drug trade.

«My words have been grossly mischaracterized and taken out of context... I was discussing the value of treating people for using dangerous and illegal drugs like marijuana, and the context in which treatment is successful.»

People in Russia and other parts of Eastern Europe are reportedly clamoring to get their hands on the drug Maria Sharapova used for 10 years and which caused her to fail a drug test during the Australian Open tennis tournament in January.

«Even if it remains a Schedule I substance, the DEA will continue to allocate its resources and time to the biggest and most violent drug traffickers,» he says, explaining most of the agency's resources are being used to deal with the current opioid epidemic, which kills more people each year than auto accidents.

The judge suggested that her decision to come down so harshly was in part due to Ulbricht's attempt to hire hit men and in part by the scale of the operation, which led drug dealers using Silk Road to customers across the world.

If it works, it could be used in a far greater number of patients than Sarepta's drug, which is approved for a relatively small slice of the DMD patient pool.

These types of drugs could potentially be used with other sorts of immunotherapies, which are all the rage in biopharma these days.

So, Loncar took matters into his own hands and created a new type of biotech index that focuses exclusively on the red - hot field of cancer immunotherapy drugs (treatments which use the body's immune system as a conduit to fight cancer).

This arrangement — which prosecutors have admitted to in court — raises serious questions about the government's use of informants and the often blurry methods it uses to combat drug trafficking syndicates.

The priority review user fee required by this subsection shall be due upon the submission of a human drug application under section 505 (b)(1) or section 351 (a) of the Public Health Service Act for which the priority review voucher is used.

Leerink's bullish Geoffrey Porges expects the big biotech, in bad need of some positive R&D developments after a string of setbacks last year, will use a priority review voucher to hustle this drug to a quick decision at the FDA, which he now expects to arrive before the end of 2017.

The Secretary approves a drug pursuant to an application submitted under section 505 (b) of this Act or section 351 (a) of the Public Health Service Act for which the sponsor of the application used a priority review voucher issued under this section.

The company focuses on cancer drug research and has a platform for so - called «real - world» data, which can be used to assess the economic value of medicines and is sought after by drug makers looking to justify their prices to health insurers.

GSK's HIV drug dolutegravir, which is used in the medicines Tivicay and Triumeq, has been the mainstay of the British group's HIV operation and investors are concerned about any threat to what is a highly profitable business.

We do this by conducting clinical trials in which we collect safety and efficacy data about our experimental drugs with the goal of submitting those data to regulatory authorities, like the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA), so that these experimental drugs can be approved for use by patients.

Tecentriq belongs to a class of drugs called PD - 1 inhibitors, which help the immune system to fight cancer by blocking a mechanism that tumors use to evade attack.

WOONSOCKET, R.I. (AP)-- CVS Health Corp. reported better - than - expected third - quarter earnings Tuesday as increased use of specialty drugs helped offset missing sales of tobacco products, which the company stopped selling this fall.

Bain and Cinven, who earlier this year took control of Germany's Stada, are hoping to use the Merck unit as a buy - and - build platform for Stada, which makes generic drugs and consumer care products and had annual revenues of more than 2 billion euros in 2016, the sources said.

Instead of ignoring reporters» questions about the price increase of the drug, which is used to treat people with toxoplasmosis, Shkreli embraced the publicity, speaking with The New York Times and other media outlets, and arguing that the price of $ 750 per pill was necessary and good business.

Among other things, it has been criticized as a scam — based on economic assumptions that are described as «laughable» — and has come under fire from the U.S. Senate for the ease with which drug dealers and other subversive elements can make use of it.

In the article, the MSM propagandist states such things as: 2017 has seen, according to his one time Goldman Sachs source, a «dramatic crash in [physical gold coin] demand,» that interest in gold coins is linked to «political conservatism, or anarcho - libertarianism» and «end of the world right wing sentiments,» that gold has been implicated in a «conspiracy to commit money laundering,» that gold is «financed by people in the narcotics trade,» that it comes from «illegal mines and drug dealers in Peru, Bolivia and Ecuador,» that «the federal authorities assume the NTR Metals [case] represented only a fraction of illegally sourced and financed gold,» that therefore the US attorney is broadly investigating the gold industry, that gold is «produced by exploited workers,» that «crude [gold] extraction techniques create serious and lasting environmental damage,» that gold plays an important part in «tax evasion,» that it is related to American gun sales, which the author abhors; that «drug dealers [use] gold imports as a way of laundering their proceeds,» and that «they came to realize that illegal gold [is] an intrinsically better business» than drug dealing; to name but a few of the aspersions cast against gold in the short article.

One of the few negatives on an otherwise fairly positive day of trading was the 5 % decline of Reckitt Benckiser, producers of a drug used to help get drug users off of Heroin called Suboxone, which acts as a replacement for the Class A. Reckitt's patent for Suboxone is due to expire in the relatively near future, so they have been trying to push doctors and other pharmaceutical vendors towards their film version of the drug, which is still under patent and will be for quite some time.

But topping the list is Vertex (VRTX), which has a veritable plethora of HCV drugs in late - stage clinical trials, which are used either alone, or in combination with other drugs.

The startup describes itself as a deep data platform for the study of exosomes, which are small lipid vesicles — air - or fluid - filled cavities — that are excreted from cells and which deliver information that Mantra plans to use to come up with new drug therapies.

Folman's adaptation attempts to update some of the themes of Lem's book to fit our modern obsession with entertainment, but the original novel is more about the use of psychotropic drugs to create a dream world in which everyone thinks himself happy.

It is, in other words, one of the most toxic, dangerous, and potentially fatal drugs in the entire PDR, and it has been approved for use by the FDA only for the treatment of cancer — which is to say, the dangers of this drug are so massive that they are outweighed only by the benefit of abating or curing cancer.

Once St. Paul told Timothy he should use some wine as a drug, and wine was ever used at the Lord's Supper which is one of the most holy actions of the Church.

But thousands of youth dabble in drug use, particularly «pot,» to share in a peer - group ritual, for a «peak experience,» or simply to try something exciting of which the square adult world vigorously disapproves.

Although the code identified a list of banned topics, via its «general principles» («be carefuls») and its «particular applications» («don'ts»), the Hays Office couldn't stop filmmakers from skirting or ignoring its recommendations, which included: no use of profanity or depictions of nudity; no mention of drugs, perversion, prostitution, miscegenation, or venereal disease; no ridicule of clergy or creed, race or nation.

The Federal Drug Administration has recently authorized use of DES (diethylistilbestrol), a strong estrogen which functions to influence uterine contractability and to diminish the receptivity of the endometrium to implantation of a fertilized ovum.

And they even predict that decriminalization will take the stigma out of drug use, which will help people get help to beat addiction to drugs.

They challenged routine procedures such as the episiotomy, the use of pain - killing drugs, and the use of forceps, which sometimes resulted in damage to the newborn.

Prisoners of the state, under the gun for using or dealing in a drug which is relatively harmless.

Instead of punshing these 200 students who rely on this medical insurance for their health, how about you have faith that your students will not use or have need of the drugs and treatments with which you disagree?