Sentences with phrase «use of mice bred»

Making use of mice bred for developing Alzheimer's like symptoms, the researchers provide evidence that caffeinated coffee protects against the disease which isn't possible with other beverages that contain caffeine or decaffeinated coffee.

Not exact matches

«Each animal bred or used for research, whether a mouse, fish or monkey, is an individual capable of experiencing pain, suffering and distress.

Tohru Mizushima of Kumamoto University, Japan, and his colleagues used mice bred to mimic symptoms of Alzheimer's.

Tohru Mizushima of Kumamoto University, Japan, used mice bred to mimic Alzheimer's symptoms.

Most animal studies of the disease are conducted with laboratory mice that have been genetically engineered and bred to model ALS, but for this research, investigators used rats with ALS because they more accurately portray the disease's variable course in humans.

The researchers performed the studies using mice bred to carry gene alterations that disrupt the production of the same mitochondrial enzyme that is defective in patients with MMA.

The researchers used mice bred to lack a functional version of the protein Ly49H, a receptor protein found on the surface of NK cells that recognizes and binds to m157.

In June, he and his colleague Thaddeus Stappenbeck argued in Nature that all mouse studies should use littermate controls: When studying the activity of a particular gene, breed mice with and without that gene by starting with heterozygous parents.

Using mice bred to lack some types of lymphoid cells, among other features, researchers were able to show that those mice still had high levels of suPAR and proteinuria, indicating that lymphoid cells were not the perpetrators of kidney disease.

She speculates that the capability could have emerged by chance after generations of breeding and inbreeding for mice used in special experiments.

Geisert and colleagues investigated genes that affect corneal thickness using strains of specially bred mice.

DJ - 1 + / −; PolgWT / MT mice were then bred with each other to produce the cohorts of mice used in this study.

A, Double heterozygous mice were bred to generate the four genotypes of mice used in this study.

Smaller, cheaper and easier to breed than mice, zebrafish in their juvenile phase can actually live in the tiny amount of liquid — ranging from tens of nanoliters to several milliliters — that fits in the wells of a standard 96 - well plate used to screen drug compounds.

The RECIPIENT (i) shall register the alleles carried by mice with a new mutation engineered from the MATERIAL with Mouse Genome Informatics (MGI), and (ii) is requested to submit breeding pairs to a public repository for cryopreservation and distribution to third parties for non-commercial purposes on terms substantially the same as these Conditions of Use.

Using a model where K - ras acts as an oncogene and initiates tumor formation, mice that were bred to not have Notch1 function showed an almost uniform distribution of about two cancerous lesions per mouse after 6 weeks, compared with approximately 14 tumors / mouse for those with Notch1 function still remaining.

The list of pesticides that have been shown to be endocrine disrupters, and which are used in the Bitterroot Valley, includes 2, 4 - D, picloram, benzene, benzoic acid, atrazine, nonylphenols and others.11 Many pesticides have either not been tested for endocrine disruption, or they have been tested using the CD - 1 mouse species, which have been bred to be genetically more resistant to endocrine disruption than other mouse strains.

Using mice that have been bred to genetically develop Alzheimer's disease, scientists set to determine the effect of grape polyphenols on cognitive decline.