Sentences with phrase «use of mice with»

Through the use of mice with transgenic expression of CD1a, we...

To address this question, the researchers made use of mice with mutations that affect different aspects of synapse unsilencing.

Not exact matches

The Surface Pro runs Windows 10, which (unlike Windows 8) is a full - blown desktop - first OS, and as such it works perfectly with peripherals like an external mouse and all of the legacy Windows apps many people use every day.

The following techniques can be used to gather market information with the help of a few mouse clicks and keystrokes:

If you've used an Apple mouse (IDEO fashioned the company's first, in 1980), swept with a Procter & Gamble (PG) Swiffer (it collaborated on the hit), or even stood in line at an airport recently (the firm has worked with the Transportation Security Administration to make the process friendlier), you've felt the legacy of David Kelley.

We'd ask [with the first Apple mouse], should you use the mouse with your fingertips or slide it like a bar of soap?

Users can perform complex 3D actions using hand movements — where the engine can independently track your head and both hands, each with six degrees of freedom — versus a mouse with just two degrees of freedom.

Using a «gnotobiotic mouse model» — where mice were «colonized with a synthetic human gut microbiota composed of fully sequenced commensal bacteria» — Desai et al reported on the effects of different diets with different fibre content.

i added a bit of oil olive to the dough and subbed pecans as i didn't have walnuts and used 1/2 bread flour and doubled the recipe as i wanted a super mega size loaf, going to use it for turkey sandwiches along with a tomato soup, can't wait for dinner, I'm so excited to find pom recipes as well, the chocolate dipped shortbread looks like christmas on a plate!Re; your mouse inthe house, we lived thru an infestation, only problem the children thought they were pets at the time!

Hassles such as buying paper towels or searching for the perfect used car that used to require legwork, human interaction, and possibly even wearing pants can now be done with a click of a mouse from one's own living room.

Not only can these Mickey Mouse Stickers make the perfect reward system when used as potty stickers and teamed with one of our FREE Potty Training Charts, but they can also be added to a potty chair to make a decorative statement!

With a tap of your phone or a click of a mouse you can now find out exactly what crimes are occurring in your neighborhood even the date and time they happened by using the NYPD's new CompStat 2.0 website.

The first and newest FDA - approved treatment of nusinersen doesn't completely cure the disease, so Sumner's research team wanted to see if using ASO - A in conjunction with nusinersen would further improve muscle form and function in mice with spinal muscular atrophy.

In the new work, published June 10 in the journal Scientific Reports, Zhao, Reid and colleagues used a highly sensitive probe to measure electrical fields in the corneas of isolated eyes from three different lab mouse models with different types of diabetes: genetic, drug - induced and in mice fed a high - fat diet.

The scientists are also experimenting with gene therapy, using a harmless virus to deliver a normal copy of the normal CIB2 gene to baby mice that have the mutated version.

A smart auto - sleep function will turn off the mouse when not in use to save battery, and it is compatible with most versions of Windows.

Using the mouse as an experimental model, LMU neurobiologist PD Dr. Conny Kopp - Scheinpflug and her research group have now demonstrated that the activity of nerve cells in the auditory system has a direct effect on myelinization — higher levels of activity correlate with the formation of thicker myelin sheaths.

For researchers using mouse models to study a variety of cancers, including lymphoma, melanoma, breast, and prostate cancers as well as autoimmune and infectious diseases, the panel facilitates a highly sensitive and high - throughput investigation of biomarkers associated with disease progression.

These findings allowed researchers to create a chimera virus: a mouse virus with a human viral gene that can be used to test molecules that inhibit human LANA protein in an animal model of disease, treating not only human herpes virus infection but also its associated cancers.

Shukla and colleagues discovered that a small drug molecule called BX795, which is sold to labs for use in experiments, helped clear HSV - 1 infection in cultured human corneal cells, in donated human corneas, and in the corneas of mice infected with HSV - 1.

Alcino Silva, distinguished professor of psychology at UCLA, has been using genetic markers and a highly miniaturized microscope to zero in on sets of brain cells in mice with such interconnected or «linked» memories.

The mouse is compatible with most versions of Windows and Mac operating systems, and you can use it right out of the box without having to install any drivers.

For this study the researchers targeted very specific types of GABA receptors to improve social behaviors with clonazepam, but the team also found that by using a different drug, they could target other GABA receptors and actually reduce the ability to socially interact in normal mice — underscoring that future medications would need to target very specific receptors so as not to diminish the drug's impacts.

The positive effect of sialic acid Neu5Gc on the respiratory system was confirmed using a mouse - model: The Neu5Gc molecules consumed with food improved the pulmonary function of the mice, therefore reducing asthma symptoms.

Like the Rosetta Stone that scholars used to decode hieroglyphics, researchers trained the algorithm with more than 4,600 T cell receptors and then used it to correctly assign 81 percent of the human T cells and 78 percent of mouse T cells to one of 10 different viral epitopes.

Using a novel form of gene therapy, scientists from Harvard Medical School and the Massachusetts General Hospital have managed to restore partial hearing and balance in mice born with a genetic condition that affects both.

Wherry and his collaborators used PD - 1 knockout mice infected with lymphocytic choriomeningitis virus to see whether the genetic deletion of PD - 1 would be enough to prevent T cell exhaustion.

Researchers used tissue and blood samples to show that the gammopathy (a precursor to myeloma) in both mice and patients with Gaucher disease is triggered by specific lipids, and that the antibodies made by tumor cells in nearly a third of myeloma patients are directed against such lipids.

Green and co-workers worked out a gentler approach using druglike molecules to kill microglia in the brains of mice with simulated Alzheimer's disease.

Using «freshman physics,» neuroscientists have deployed electric fields to stimulate neurons buried deep in the brains of mice — a method that could one day lead to noninvasive therapies for people with Parkinson's disease and other brain disorders.

Using immunostaining, the researchers counted the remaining tumor cells; the mice treated with GD2 CAR - T cells had a few dozen remaining cancer cells per animal, while each control mouse had tens of thousands of cancer cells.

Using a surgical technique called parabiosis to join the circulatory system of a young mouse with that of an old one, the researchers studied the effects of young blood on elderly cells, and vice versa.

When the team used the retinoid fenretinide along with anti-estrogen therapy in mouse models of breast cancer, they did not see the expansion of CK5 + cells previously seen with anti-estrogen therapy alone.

Experiments with a compound called TNP [N2 -(m - Trifluorobenzyl), N6 -(p - nitrobenzyl) purine], which researchers often use to study obesity and diabetes, show that in mice the therapy can promote the formation of new bone.

In this study, the Hiroshima University researchers developed an animal model using severely immunodeficient mice whose livers were partially populated with human cells, in order to reconstruct elements of the human immune system.

Part of the problem, he says, is that the incidence of many human chronic diseases rises with age, yet many researchers prefer using young mice because of the pressures of being published and getting funding.

Researchers at The University of Texas MD Anderson Cancer Center developed a novel chimeric mouse model to test the combination therapy using immune checkpoint blockades with therapies targeting myeloid - derived suppressor cells (MDSCs).

When researchers used optogenetics — a technique that allows cells to be switched on and off with light — to increase the amount of bursting in the lateral habenula, mice behaved in a more «depressed» way, remaining motionless when forced to swim in a container of water, for example.

In this study, the researchers used two groups of mice with different types of colitis, chronic and acute.

Most recently, they have taken mice in late middle age and lengthened the remainder of their lives by an average of 30 to 40 percent with a drug called rapamycin, an antifungal agent also used to suppress immune responses in transplant patients.

The researchers used mice with skin like that of red - haired, fair - skinned people, who don't tan because of a nonfunctioning protein on the surface of the skin cells that make melanin.

To ensure the introduced protein didn't interact with other parts of the neuron, the team used the mouse version of the gene rather than the nematode's usual invertebrate version.

Badylak, along with Tufts University biomedical researcher David Kaplan and Susan Braunhut of the University of Massachusetts Lowell, is using a device called a bio-dome, a sleeve with a liquid reservoir that envelops an amputated mouse digit and allows researchers to control the healing environment.

The researchers used Attenuated Total Reflectance Fourier Transform Infrared (ATR - FTIR) spectroscopy to examine the blood serum of mice with colitis and found nine absorption peaks that could be used to indicate the presence of the disease in the blood sample.

In one, researchers working with mice at the Institute of Molecular and Cellular Biology in Singapore used antibodies to target proteins inside cancer cells — an impressive feat, since the antibodies were long considered too large to cross the cancer cell's outer membrane.

Professor Bischofberger and co-investigators Stefanie Heigele, PhD, and Leoni Bolz tested two groups of mice, which were housed either without (sedentary) or with running wheels (voluntarily running) using a novel object recognition (NOR) task to assess learning and long - term memory.

Hearing loss in mice with a form of progressive deafness has been slowed by a one - off treatment using the CRISPR genome editing method.

«The researchers also overdosed the mice tested in their study with levels of the ingredient at a rate hundreds of times greater than what would be consider a safe use level (based on EPA standards),» DeLeo said in an email.

They injected the particles directly into mice with an experimental human brain cancer, and into the brains of healthy mice for use as comparison.

Psychologists hope that a deeper understanding of how our left and right hands cooperate will lead to the development of intuitive two - handed user interfaces that give us more control over computers than the mouse we use with one hand today.