Sentences with phrase «use of nanoparticles for»

The successful use of nanoparticles for delivering and concentrating antimicrobial molecules to the site of infections should allow the use of antibiotics that have proved their efficiency in vitro but that show poor in vivo bioavailability.

The technique could facilitate the use of nanoparticles for optical, electrical, optoelectronic, magnetic, catalysis and other applications in which tight control over size and structure is essential to obtaining desirable properties.

Not exact matches

Phase I funding — which allows up to $ 250,000 for an academic idea, such as decoding the genetic sequence of a protein or studying targeted drug delivery by using magnetic nanoparticles — is available from federal funding and foundations.

Cambridge, MA — February 6, 2017 — Aura Biosciences, a biotechnology company developing a new class of therapies to target and selectively destroy cancer cells using viral nanoparticle conjugates, announced today that the U.S. Food and Drug Administration (FDA) has cleared the investigational new drug application (IND) for the company's lead program, light - activated AU - 011 in ocular melanoma (OM).

Cambridge, MA — March 30, 2017 — Aura Biosciences, a biotechnology company developing a new class of therapies to target and selectively destroy cancer cells using viral nanoparticle conjugates, announced today that it has enrolled and dosed the first patient in its Phase 1b clinical trial of light - activated AU - 011, an investigational, first - in - class targeted therapy in development for the treatment of ocular melanoma, a rare and life - threatening disease.

«We envision that these photo - responsive polymer - capped gold nanoparticles could one day serve as nano - carriers for drug delivery into the body using our robust and reversible process for assembly and disassembly,» said Zhiqun Lin, a professor in the Georgia Tech School of Materials Science and Engineering.

As a proof of concept for this study, the researchers tested the plant virus - derived nanoparticles with a nematicide called crystal violet, which has been used to kill nematodes on skin but not in agriculture.

In a paper published in the current online issue of the journal Small, titled «Immune Cell - Mediated Biodegradable Theranostic Nanoparticles for Melanoma Targeting,» the researchers report the use of a novel biodegradable and photoluminescent poly (lactic acid) nanoparticle, loaded with melanoma - specific drugs with immune cells as the nanoparticle carriers.

«For years, researchers have focused on delivering more chemotherapy drugs into cancer cells using nanoparticles, without targeting the root of drug resistance,» He said.

A «Trojan horse» treatment for an aggressive form of brain cancer, which involves using tiny nanoparticles of gold to kill tumour cells, has been successfully tested by scientists.

In earlier work, Demir Akin of Stanford University and his colleagues used antibodies and nanoparticles to attach molecules of DNA to weakened Listeria monocytogenes, which is a bacterium responsible for many cases of food poisoning.

A technique using anesthesia - containing nanoparticles — drawn to the targeted area of the body by magnets — could one day provide a useful alternative to nerve block for local anesthesia in patients, suggests an experimental study in the April issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

Magnet - directed nanoparticles have previously been used for targeted delivery of chemotherapy drugs.

To demonstrate one potential use of the nanoparticles, the research team used them as advanced catalysts for ammonia oxidation, which is a key step in the production of nitric acid (a liquid acid that is used in the production of ammonium nitrate for fertilizers, making plastics, and in the manufacturing of dyes).

In general, catalysts are rare metals (platinum, for example), which are often used in the form of nanoparticles.

Use of nanoparticles in many applications, e.g. for catalysis, relies on the surface area of the particles.

The tiny nanoparticles used for catalysis often consist of only a few platinum atoms.

«We think the use of the mRNA nanoparticle provides an additional level of safety by making sure the enzyme is not present for too long a period of time.»

Using nanoparticles designed and screened for endothelial delivery of short strands of RNA called siRNA, the researchers were able to target RNAi to endothelial cells, which form the linings of most organs.

To demonstrate the potential for treating lung disease, the researchers used the nanoparticles to block two genes that have been implicated in lung cancer — VEGF receptor 1 and Dll4, which promote the growth of blood vessels that feed tumors.

Scientists at the U.S. Naval Research Laboratory (NRL) Materials Science and Technology Division have developed a novel one - step process using, for the first time in these types of syntheses, potassium superoxide (KO2) to rapidly form oxide nanoparticles from simple salt solutions in water.

But that is precisely what Yuebing Zheng, assistant professor of mechanical engineering at The University of Texas at Austin, is working toward with his «nanotweezers» — a new tool for handling nanoparticles using light that could create opportunities for innovations in nanotechnology and individual health monitoring.

Wang's research group designed a five - metal catalyst based on these high - entropy - alloy nanoparticles and demonstrated superior catalytic performance for selective oxidation of ammonia to nitrogen oxide, a reaction used by the chemical industry to produce nitric acid, an important chemical in the large - scale production of fertilizers and other products.

While on one hand, there is significant potential in the application of nanoparticles in enhancing heat transfer for tumor ablation and targeted drug delivery, there is also much promise in improving imaging and diagnostic protocols using them.

Cooperation with the local university is important for Oxonica, says Gareth Wakefield, Oxonica Vice-President Research, Co-founder, and a physicist by training, as the company uses some of the university equipment for the characterisation of the nanoparticles.

For this project, Mahler expanded her GI tract model to include a commensal intestinal bacterial species and used the model to determine a more detailed mechanism of the role of nanoparticle exposure on gut bacteria and intestinal function.

For this reason, the use of the nanoparticle would be very beneficial for female patienFor this reason, the use of the nanoparticle would be very beneficial for female patienfor female patients.

However, they still have to be cautious and select the best concentration of nanoparticles to use for maximum benefit, Biswas says.

Scientists charged these batteries with different levels of current for various periods of time, took them apart and used a brilliant X-ray beam to see how the charge was distributed among billions of nanoparticles in the positive electrode.

By applying an innovative theoretical analysis to observations from a first - of - its - kind experimental setup, LANP graduate student Bob Zheng and postdoctoral research associate Alejandro Manjavacas created a methodology that solar engineers can use to determine the electricity - producing potential for any arrangement of metallic nanoparticles.

«These findings open up new opportunities for using nanoparticles as a platform for combination therapies,» said Yu - Ying He, an associate professor of medicine and dermatology at UChicago who is familiar with the work.

The researchers used computational modeling to investigate different surface features of palladium nanoparticles that may be responsible for hydrogen peroxide decomposition.

Tracer or sensor particles added to fracturing fluids help solve that problem, but there's plenty of room for optimization, especially in minimizing the volume of nanoparticles used now, he said.

A team headed by Yen Hsun Su of the Research Center for Applied Sciences at the Academia Sinica in Taipei, Taiwan, dipped Bacopa caroliniana, a plant often used in aquaria, into a solution of gold nanoparticles.

«But the heat needed for most applications of silver nanoparticles has limited their use.»

For example, farmers have used silver nanoparticles as a pesticide because of their capability to suppress the growth of harmful organisms.

«Lastly, the technique we have pioneered will likely be a valuable tool for scientists and clinicians studying the biology of complex nanoparticle populations,» Dr. Zhang said, «and may aid in the development of diagnostic tests using them as biomarkers.»

«RNAi therapies are a unique approach to cancer treatment as they have the potential to «turn off» the genes» coding for proteins involved in cancer cell division,» said Ramesh K. Ramanathan, M.D., medical director of the Virginia G. Piper Cancer Center Clinical Trials Program at Scottsdale Healthcare and deputy director of the Clinical Translational Research Division of the Translational Genomics Research Institute (TGen) in Phoenix, Ariz. «Using a lipid nanoparticle, the RNAi drug can be delivered to a cancer cell to block the expression of specific proteins involved in tumor growth.»

about PPPL launches expanded new laboratory for research on the use of plasma to synthesize nanoparticles

Working with a world - leading group at the University of Connecticut in the USA, who pioneered the development of self - assembling protein nanoparticles (SAPNs) for vaccine design, they have used advanced mathematical calculations to create a complete picture of the surface morphology of these particles.

«The ability to target tumors is one of the primary reasons for using nanoparticles as therapeutics to treat solid tumors.»

The HZI will develop a vaccination protocol for mucosal administration based on three novel strategies: (i) development and optimization of a vaccination protocol in which parenterally - primed T and B cells are subsequently pulled into the mucosa by the local delivery of the cognate antigen to the requested effector site, (ii) testing the co-administration of antigens with novel mucosal adjuvants using different mucosal immunisation routes and schedules, and (iii) testing various nanoparticles co-administered with different immunomodulators for their ability to generate both systemic and mucosal immune responses following transcutaneous / trans - follicular vaccination.

The team used iron oxide for the core of the nanoparticles, which not only enables the team to use them for magnetic resonance imaging, but opens up possibilities in remote guidance and localized magnetic heating to hasten the breaking up of the clots.

School of Allied Health Sciences» Steen Madsen is exploring new treatment methods for primary brain tumors — tumors that originate in the brain — using nanoparticles and lasers.

«If we use the results of this paper [published in the Journal of Physical Chemistry B], we can grow nanoparticles in the confined matter to create larger, uniformly sized nanoparticles of metal oxides, such as titanium dioxide, which is very important to creating the materials you need for electrodes for batteries,» said Sushko.

The first direct comparison of in vitro and in vivo screening techniques for identifying nanoparticles that may be used to transport therapeutic molecules into cells shows that testing in lab dishes isn't much help in predicting...

Using tiny snippets of DNA as «barcodes,» researchers have developed a new technique for rapidly screening the ability of nanoparticles to selectively deliver therapeutic genes to specific organs of the body.

Other uses of new chemical technologies include tracers and reporters for geomapping and well connectivity, as well as different types of fluid loss agents that prevent formation damage or keep well integrity, and smart and stimuli - responsive nanoparticles that can be used for improving gelation.

ASTM E2834, Guide for Measurement of Particle Size Distribution of Nanomaterials in Suspension by Nanoparticle Tracking Analysis (NTA), and ASTM E2859, Guide for Size Measurement of Nanoparticles Using Atomic Force Microscopy, are both under the jurisdiction of Subcommittee E56.02 on Physical and Chemical Characterization.

The researchers now plan to tweak the nanoparticles for direct use in human patients, working to evaluate the safety of the method prior to potential clinical trials.