A large Australian trial showing that daily
use of nicotinamide, a form of vitamin B3, for 12 months reduced the incidence of new non-melanoma skin cancers by 23 % in patients at high risk for skin cancer
Not exact matches
The team found another unique aspect
of the ubiquitination process is the
use of a molecule named
nicotinamide adenine dinucleotide, or NAD, as a source
of energy.
Mammal sirtuins are NAD + - dependent deacetylases that
use NAD + as cofactor for catalyzed reactions to cleave acetyl groups from acetylated lysine residues
of target proteins, generating
nicotinamide (NAM) and 2 ′ - O - acetyl - ADP - ribose.
Next, seven
of the 27 components (pantothenate, choline,
nicotinamide, histidine, proline, pyridoxine and inositol) were retested
using an in vitro trans - epidermal diffusion experimental model, providing a functional assessment
of barrier properties (Watson et al. 2006).