Not exact matches
• The
use of biotech to provide
precision medicine for targeted therapies.
«Instead
of using non-targeted drugs that have lots
of collateral damage we thought we could take advantage
of the
precision of the immune system, in particular, antibodies,» said David Scadden, MD, Co-director
of HSCI, the Gerald and Darlene Jordan Professor
of Medicine at Harvard University, and senior author on the paper.
Scientists are bringing
precision medicine to rheumatoid arthritis for the first time by using genetic profiling of joint tissue to see which drugs will work for which patients, reports a new Northwestern Medicine multi-sit
medicine to rheumatoid arthritis for the first time by
using genetic profiling
of joint tissue to see which drugs will work for which patients, reports a new Northwestern
Medicine multi-sit
Medicine multi-site study.
Duke researchers in genomics and
precision medicine have spent the past decade exploring strategies for differentiating bacterial and viral infections with the goal
of developing cost - effective diagnostic tools doctors could
use in their offices.
The new findings could be
used to inform
precision -
medicine approaches that help minimize a person's risk for common diseases — such as diabetes, cardiovascular disease and cancer — by tailoring diet - based prevention and therapy to the specific needs
of an individual.
Reference materials are critical to properly evaluate the next - generation
of gene sequencing and genetic testing methods that will increase the reliability and effectiveness
of precision medicine (also known as «personalized
medicine»), in which a person's genetic profile is
used to create treatments and therapies unique to that individual.
Other biomarkers and genetic signatures are being
used in an effort to predict the aggressiveness
of an individual patient's prostate cancer, «but the current information doesn't make it possible for their gene signature to be an actual target for
precision medicine targeted therapy,» Ellis explained.
MacConaill noted that the results
of Profile genomic testing are being
used to further research within the institutions and are being shared more widely with initiatives like Project GENIE
of the American Association for Cancer Research (AACR), which will help advance the field
of precision medicine.
It is a development they say could enable these tools to be targeted to specific parts
of an individual's genome for
use in
precision medicine, developing therapies and treating disease.
This study is good example
of a
precision medicine themed approach to showing how a mechanistic understanding
of the differential gene expression can yield biomarkers that can be
used for early detection
of disease, as well as potential therapeutic targets.
«Our goal at QBI is to help make
precision medicine a reality by
using quantitative research tools to understand the underlying biology behind different disease states, and then to
use that knowledge to develop novel diagnostics and therapies and put them into the hands
of clinicians,» said Krogan.
Cancer researchers are increasingly
using advanced technologies that are capable
of providing far more information and detail than was previously possible, propelling the shift toward
precision medicine.
The GDC will support clinical trials that focus on single patients, known as «n
of 1» clinical trials, and will become an important component in how
precision medicine is
used to treat individual patients.
Dr. Clive Svendsen
of Cedars - Sinai will discuss a
precision medicine program that
uses patient cells to gain insights about intestinal diseases that have a strong genetic component.
Vice President Joe Biden's «Cancer Moonshot» initiative is an example
of precision medicine in its goal
of using big data and
precision oncology techniques.
Two new
precision medicine tests that look beyond cancer genes to identify novel therapeutic targets have just received New York State Department
of Health approval and are now available to both oncologists and cancer researchers for
use at the front lines
of patient care.
Together, they will provide a snapshot
of the current state
of the art in IRD research,
use it as a context to discuss the best practices for transforming genetic discoveries into personalized
precision medicine.
The focus
of Dr. Smoller's research interests has been 1) understanding the genetic and environmental determinants
of psychiatric disorders across the lifespan; 2) integrating genomics and neuroscience to unravel how genes affect brain structure and function; and 3)
using «big data», including electronic health records and genomics, to advance
precision medicine.
Using a rapid learning approach, the goal
of M2Gen is to accelerate the science
of precision medicine by creating evidence and knowledge - based solutions that identify a patient's susceptibility to disease, predict how the patient will respond to a particular drug, and match patients to the best therapies for an optimal treatment outcome.
Researchers are hopeful that proteogenomics, the integrated study
of proteomics and genomics, may improve our ability to prevent, diagnose, and treat cancer at the molecular level
using precision medicine.
To add clarity to the language
used by oncologists and basic scientists within the context
of precision medicine, the ESMO Translational Research and Personalised Medicine Working Group has developed a standardised glossary of relevan
medicine, the ESMO Translational Research and Personalised
Medicine Working Group has developed a standardised glossary of relevan
Medicine Working Group has developed a standardised glossary
of relevant terms.
In the world
of medicine, it
uses the
precision of engineering.
Tuning Forks are
used in the realms
of medicine, music, and science for a variety
of applications but their
precision also makes them ideal for
use in sound therapy, influencing the capacity
of the human body to vibrate with pure sound.
In
precision medicine, molecular profiling
of an individual patient's tumor is
used to identify genetic mutations that drive that...