Sentences with phrase «use of stem cells from»

There are no ethical or moral concerns with the use of stem cells from one's own body as these cells are adult and not embryonic.

Research involving the derivation and use of stem cells from cadaveric foetal tissues is permissible, subject to the informed consent of the tissue donor.

Research involving the derivation and use of stem cells from adult tissues is permissible, subject to the informed consent of the tissue donor.

Not exact matches

Since its foundation in 2005, the NYSCF has become a leader in using stem cell research and technology to find cures for a range of diseases, from heart disease and diabetes to Alzheimer's and Parkinson's.

This includes a stem cell research centre, a network of drug discovery institutes and a # 20 million global clinical development fund dedicated to supporting Phase I and II clinical trials; and a # 2 million collaboration between University of Cambridge and University College London that will use donated cells from people with Alzheimer's to test potential new treatments

Before you scream too loudly over this move by President Obama, keep in mind that the prohibition for using federal funds under the executive order by President Bush did not stop the practice of harvesting stem cells from unused embryos in fertility clinics.

According to Science Daily, Dr. Nagy, senior investigator at the Samuel Lunenfeld Research Institute of Mount Sinai Hospital, there is a «new method of generating stem cells that does not require embryos as starting points and could be used to generate cells from many adult tissues such as a patient's own skin cells.»

The difficulties associated with obtaining nerve tissue at the correct stage of development and differentiation from aborted embryos means that foetal tissue transplantation is no longer in favour, but the creation of human embryos specifically as sources of stem cells, and the push to use «spare» embryos from IVF treatments is gatheringmomentum.

If ESCR using «excess» embryos from IVE» continues, the next step will likely be the pursuit of such «therapeutic» cloning — the creation of embryos through somatic cell nuclear transfer (SCNT) to provide individually tailored stem cell therapies.

As we read this history, the furor over stem cells was fueled by numerous factors: the near - universal human desire for magic; patients» desperation in the face of illness and their hope for cures; the belief that biology can now do anything; the reluctance of scientists to accept any limits (particularly moral limits) on their research; the impact of big money from biotech stocks, patents, and federal funding; the willingness of America's elite class to use every means possible to discredit religion in general; and the need to protect the unlimited abortion license by accepting no protections of unborn human life.

Whilst acknowledging that many questions remain unanswered in the debate between those who would advocate the use of stem cells taken from human embryos, and those experimenting on stem cells drawn from tissues of the adult human body, there is a lengthy discussion of the moral status of the human embryo as being a crucial matter in this regard.

In addition, there may be applications where the use of one's own stem cells are needed, even if stem cells from an identical twin are available.

As well as allowing the use of stem cells grown from established cell lines, the technology could enable the creation of improved human tissue models for drug testing and potentially even purpose - built replacement organs.

The Muotri lab uses induced pluripotent stem cells from patients with autism and schizophrenia to look for biomarkers of these conditions.

Trials of cells made from human embryonic stem cells are also poised to begin in people with type 1 diabetes and heart failure, the first time embryonic stem cells have been used in the treatment of major lethal diseases.

Both diseases result from the death of retinal cells, a process that Lanza suspects can be slowed or even halted using stem - cell - derived replacements.

Working with Skeletal Biologists at Southampton General Hospital, Catarina is investigating new optical techniques to monitor the development of the cells, used in new regenerative medicine approaches — in this case, to create and grow cartilage from human stem cells.

For Konrad Hochedlinger of the Harvard Stem Cell Institue, it was a bad start to the week: Just after 6 a.m. last Monday, he and a bevy of others received an unsigned e-mail from a virtually untraceable address, [email protected], pointing out what it said «appears to be duplicated images and embryos used in a Nature manuscript published in 2009.»

Using a mathematical model known as the Ising model, invented to describe phase transitions in statistical physics, such as how a substance changes from liquid to gas, the Johns Hopkins researchers calculated the probability distribution of methylation along the genome in several different human cell types, including normal and cancerous colon, lung and liver cells, as well as brain, skin, blood and embryonic stem cells.

The Porteus team started with human stem cells from the blood of patients with sickle cell disease, corrected the gene mutation using CRISPR and then concentrated the human stem cells so that 90 percent carried the corrected sickle cell gene.

But the factor that may make the discovery very significant is that umbilical cord blood can be saved, stored and multiplied without any of the ethical dilemmas facing embryonic stem cell use, which are derived from human fetuses.

Research involving the derivation and use of embryonic stem (ES) cells is permissible only where there is strong scientific merit in, and potential medical benefit from, such research.

In addition, where cells derived from embryonic stem cells are great at proliferating — a potentially critical feature if one wants to grow sufficient numbers of cells for clinical use — ones from the iPS lines were much feebler.

The act of reprogramming cells to make them as capable as ones from embryos apparently can result in aberrant cells that age and die abnormally, suggesting there is a long way to go to prove such cells are really like embryonic stem cells and can find use in therapies.

ERRORS have occurred in a type of stem cell that could be used instead of embryonic stem cells — and in tissues made from them.

One example of this research is the practice of using stem cells taken from a healthy eye's limbus, the area around the cornea where stem cells are stored, to create a layer of healthy cells to replace damaged ones in the cornea, the transparent, dome - shaped layer of cells covering the front of the eye.

Most of those errors stem from the cell - lysis protocols scientists have been using.

The Champalimaud Center for Translation Eye Research (C - TRACER), part of the LV Prasad Eye Institute in Hyderabad, India, will continue research begun by LV Prasad scientists, who use eye stem cells from living adults to grow new cells that are then implanted into damaged eyes.

We don't need to use a cocktail of small molecules, growth factors or other supplements to create a population of bone cells from human pluripotent stem cells like induced pluripotent stem cells,» Varghese said.

The stem cells, derived from human umbilical cord - blood and coaxed into an embryonic - like state, were grown without the conventional use of viruses, which can mutate genes and initiate cancers, according to the scientists.

The new method, described in the journal Stem Cells Translational Medicine, could be used to generate large numbers of muscle cells and muscle progenitors directly from human pluripotent stem ceStem Cells Translational Medicine, could be used to generate large numbers of muscle cells and muscle progenitors directly from human pluripotent stem cCells Translational Medicine, could be used to generate large numbers of muscle cells and muscle progenitors directly from human pluripotent stem ccells and muscle progenitors directly from human pluripotent stem cestem cellscells.

The researchers have now reported in the journal Nature that the normal process of blood formation differs from what scientists had previously assumed when using data from stem cell transplantations.

In May 2013, Mitalipov was the first scientist in the world to demonstrate the successful use of somatic cell nuclear transfer, or SCNT, to produce human embryonic stem cells from an individual's skin cell.

Using tumor samples from the Women's Healthy Eating and Living clinical trial, researchers identified stem - like tumor cells as being characterized by low levels of the molecule p53 upregulated modulator of apoptosis (PUMA).

To see whether cancer stem cell renewal involves a chain of events similar to that used by embryonic stem cells, and whether the process was affected by oxygen levels, Semenza and graduate student Chuanzhao Zhang focused their studies on two human breast cancer cell lines that responded to low oxygen by ramping up production of the protein ALKBH5, which removes methyl groups from mRNAs.

Instead of using white blood cells, the British researchers, working with a Dutch group, want to take stem cells from bone marrow and insert the ADA gene into these.

The research team used mass spectrometry to compare phosphorylation of proteins from mouse embryonic stem cells with fully functioning GSK - 3 to cells in which the gene encoding GSK - 3 had been deleted.

In a collaborative effort between the Gladstone laboratories of Benoit Bruneau, PhD, Katherine Pollard, PhD, and Dr. Srivastava, the scientists used stem cell technology to make large amounts of endothelial cells from patients with CAVD, comparing them to healthy cells and mapping their genetic and epigenetic changes as they developed into valve cells.

Stem cell researchers call them «a major step in the right direction,» although some were disappointed that NIH didn't open the door to the use of embryos created for research purposes — including through somatic cell nuclear transfer (cloning) and parthenogenesis (from an unfertilized egg).

Prof Tony Green, an author from the Wellcome Trust - MRC Stem Cell Institute and Cambridge University, said: «The SC3 tool was able to use patterns of gene expression to distinguish, within an individual cancer, subclones that carried different mutations.

«There have been previous reports of other labs deriving beta cell types from stem cells, no other group has produced mature beta cells as suitable for use in patients,» he said.

To unravel the complex signaling pathway map, the scientists used their own findings from the analysis of factors regulated up or down in the interplay between tissue and stem cells, linking them with the signaling pathways described in existing literature.

Last January, the House of Representatives voted, 253 to 174, to pass a bill, H.R. 3, that would allow researchers to use leftover embryos from in vitro fertilization (IVF) clinics to create new lines of embryonic stem cells, and in April, the Senate passed its version of the bill.

Using fluorescent markers, Fuchs and her colleagues isolated two distinct populations of stem cells from mouse skin.

The stem cells used to treat Paizley, specific to the blood, came from the bone marrow of a healthy adult donor.

To perform this lifesaving work, scien - tists use adult stem cells derived from the cells of mature or recently born humans or animals.

«Use of induced pluripotent stem cell (iPSC) technology» — which involves taking skin cells from patients and reprogramming them into embryonic - like stem cells capable of turning into other specific cell types relevant for studying a particular disease — «makes it possible to model dementias that affect people later in life,» says senior study author Catherine Verfaillie of KU Leuven.

• News from the World of Adult - Stem Cell Research • At the University of California at Los Angeles, Marc Hedrick's team used human adult fat cells extracted during liposuction to make cells resembling cartilage, bone, and muscle.

Previous experiments using stem cells from embryos have shown promise in replacing lost cells, but the use of these is controversial.

In recent years, Muotri and colleagues have created in vitro cellular models of autism using reprogrammed induced pluripotent stem cells (iPSC) derived from discarded baby teeth of children with autism, work dubbed the «tooth fairy project.»