Antiviral drugs amantadine and rimantadine, which for years were the most widely
used against influenza A viruses, plugged the M2 pathway like bathtub stoppers, preventing reproduction.
Not exact matches
Kang's primary research focuses on designing and developing effective vaccines
against viral diseases such as
influenza virus and RSV, but he partnered with a university and research institutes in South Korea that wanted international collaborative projects to study if ginseng can be
used to improve health and protect
against disease because of the potential benefit in fighting these viruses.
Guidelines recommend that vaccinations should be
used to protect
against certain infections, such as
influenza and pneumonia.
In an ambitious study, the authors attempt to trace drug resistance
against all strains of the flu by
using an extensive
influenza virus database containing all known genetic sequence information (70,000 complete nucleotide sequences) for
influenza strains.
Molecular biologists at Philadelphia's INB: Biotechnologies are
using the vegetable to make vaccines
against anthrax,
influenza, even plague.
Furthermore, results may encourage other research groups to
use the M2 channel of
influenza virus as therapeutic target
against the
influenza A virus.
In the new analysis, investigators sought to understand the role of pre-existing anti-HA stem antibodies in protection
against influenza using data from a healthy volunteer
influenza challenge trial that took place in 2013 at the NIH Clinical Center in Bethesda, Maryland.
Several of the antibodies we isolated have broad neutralization capacity in vitro
against divergent
influenza strains and show potent prophylactic and therapeutic activity when
used to treat mice that were lethally infected with
influenza.
On the basis of the current studies as well as previous reports on the
use of intradermal immunization
against influenza, hepatitis B, rabies, and other infectious diseases, 2,3,8 it is becoming clear that
use of the intradermal route may at least partially overcome the relatively poor
influenza - specific immune responses seen in certain at - risk populations, particularly the elderly, in whom the immune response in general is known to diminish with age.9 Moreover, in times of shortage, the dose - sparing intradermal approach might be particularly well suited to the young, healthy persons included in the CDC's high - priority group for vaccination, such as health care workers, as well as to younger, otherwise healthy populations in general.
Her research involves preclinical immunology and efficacy of vaccines
against H5N1 pandemic
influenza, malaria, and Mycobacterium tuberculosis
using mouse, ferret and guinea pig models.
According to the American Veterinary Medical Association, «Currently, there is no USDA - licensed vaccine
against H5N1 highly pathogenic avian
influenza infection available for
use in companion animals in the United States.»