Sentences with phrase «used as a model organism»

While tomatoes have been regularly used as a model organism to study the effect of climate in fruit ripening, its commercial history is a chequered one.

As a proof - of - concept, the researchers cloned more than 3,000 DNA fragments from E. coli bacteria, commonly used as a model organism with a catalogued genome sequence available.

He presented his idea one day to a roomful of about 30 colleagues at Yale's «Worm Meeting,» the weekly gathering for researchers studying C. elegans, the lowly nematode widely used as a model organism in developmental biology.

For this reason, the zebrafish is now used as a model organism by scientists around the globe.

Curran and his colleagues tweaked the amount of Maf1 in C. elegans, a transparent worm often used as a model organism by biologists.

This unicellular fungus is often used as a model organism, because it works as a mammalian cell, though it is easier to handle.

Scientists use it as a model organism for studying cellular signals, disease, and the movement of cells in response to a chemical stimulus (chemotaxis).

Given the rapid succession of generations in yeast, we can use it as a model organism — and study the mechanisms of aneuploidy in much greater detail to find out whether we can derive from it new approaches for diagnosing and treating human diseases.»

The zebrafish is used as a model organism for research into the embryonic development of vertebrates.

The team of Luis Lopez - Molina, professor at the Department of Botany and Plant Biology of UNIGE's Faculty of Science, Switzerland, has been interested for a long time in the mechanisms controlling germination, arguably the most critical decision in the life of a plant: «We have discovered that the genes involved in the synthesis of cutin, a waterproof substance, are important for the maintenance of dormancy in seeds of Arabidopsis thaliana, a small plant widely used as a model organism to study plant biology.

Zebrafish have only been used as a model organism by a lot of labs in the last 15 years or so.

This year the organizers overtly recognized the history of our biomedical research niche in which C. elegans nematodes are used as a model organism (see our SAGE blog on how C. elegans models are used to study aging).

The fruit fly, Drosophila melanogaster, is widely used as a model organism for biological and biomedical research and so such puppetry should allow the species to be studied more easily than ever before.

The researchers first discovered ascarosides as a signaling molecule in C. elegans, a nematode used as a model organism to study cell, developmental and nervous system biology, as well as human aging and diabetes.

Tetrahymena species used as model organisms in biomedical research are T. thermophila and T. pyriformis.

Not exact matches

Dennis has a PhD in genetics / developmental biology from the University of British Columbia and a special interest in studying pattern formation and cell - cell communication during tissue development using fruit flies as a model organism.

In collaboration with Synchrotron Oxford, the University of East Anglia and the University of California, the researchers, using a commonly - found member of human gut microbiota called Ruminococcus gnavus as a model organism identified carbohydrate binding modules with the ability to bind to mucus.

Protein misfolding and aggregation had been identified as a major factor in mad cow disease, and research using yeasts as model organisms played a large role in those findings.

She did her master's degree research project at the Institute of Biochemistry and Biophysics (IBB), also in Warsaw, looking at the effect of genetic mutations on the function of an enzyme involved in the biosynthesis of heme, using Saccharomyces cerevisiae as a model organism.

The research team, led by Bosch, use the freshwater polyp Hydra as the model organism to elucidate the fundamental principles of nervous system structure and function.

Using the freshwater polyp Hydra as a model organism, the Kiel - based researchers and their international colleagues investigated how the simple nervous system of these animals interacts with the microbiome.

«Using yeast as a model organism, we studied the Tup1 protein, a negative regulator of gene expression,» says Biology Professor Emanuel Rosonina, adding, «This protein binds to some genes and blocks their expression, helping to ensure genes that shouldn't be turned on remain inactive.»

Replacement alternative methods include the use of data concerning the physicochemical properties of chemicals; predictions based on structure - activity relationships, including the use of qualitative and quantitative mathematical models; the biokinetic modelling of physiological, pharmacological, and toxicological processes; experiments on lower organisms not classed as?

«Like many labs, we use C. elegans — a tiny roundworm — as a model organism to reveal important lessons about aging and autophagy,» explains Hansen.

Knowing these larvae respond to odors but not fully understanding the process by which they make decisions via olfactory cues, scientists at UC Santa Barbara are using this model organism to study brain function as it relates to behavior control.

His lab is continuing to use the zebrafish as a model organism, but Junker also sees great potential in applying the technique to human organoids.

The research team conducted experiments on the roots of Arabidopsis, a plant often used as a «model organism» in plant biology and had its genome fully sequenced in 2000.

A research group from the University of Seville has revealed the role that the protein Rrm3 plays in the repair of breaks that occur during the replication of DNA, by using the yeast Saccharomyces cerevisiae as a model organism.

Using the Drosophila melanogaster fruit fly as a model organism, the team led by Prof. Dr. Ingrid Lohmann at Heidelberg University's Centre for Organismal Studies was able to show how a special developmental gene from the Hox family influences germline stem cells.

Using a novel method they developed to map chromosome breaks in a model organism, the budding yeast, Wenyi Feng, Ph.D., of Upstate Medical University and her colleagues have discovered new information as to how and where chromosome fragile sites can occur in human DNA.

The researchers studied this adaptive bacterial life cycle using Bacillus subtilis as a model organism.

In plants, the positional cloning method has been traditionally used in studies of model organisms such as rice and Arabidopsis, providing important insights into plant genetics.

This approach opens new avenues for research into memory using zebrafish as model organism,» concludes Dr. Okamoto.

-- 90 percent of genes associated with disease are identical in the human and the mouse, supporting the use of mice as model organisms.

«The fruit fly is a well - known model organism used to understand human biology as it, like all other living organisms, has to fend off various viral infections.

A few species are studied as model organisms that can be used to gain knowledge of basic processes such as genetics, physiology, biochemistry, and molecular biology with results that are applicable to many organisms (Taylor et al., 1993).

She added, «New model systems will be a magnet for people from outside the field of marine microbial ecology as they will suddenly be able to work with marine microbes in ways that they are used to working with other model organisms.»

You no longer have to use a genome from another organism as your model.

Now, the use of diverse model organisms to explore human disease is truly starting to gain the recognition it deserves as a scientific approach.

Our group is helping Rafael Yuste's lab to pioneer the use of Hydra vulgaris, a small, freshwater polyp that attaches itself to underwater surfaces in lakes, rivers and ponds and uses its tentacles to capture prey, as a model organism for studying neural function.

The main focus is to understand how cell biology drives morphogenesis using vertebrate eye formation as a model and zebrafish as main experimental organism.

Dr. Hansen's group focused on investigating the molecular mechanisms by which the nutrient sensor TOR modulates aging, using the nematode C. elegans as her primary model organism.

We will use the fruitfly Drosophila melanogaster as an experimental model, as this tractable organism experiences age - related changes of their stem cells that are similar to the ones observed in mammals.

Biological Annotation of the Genomic Sequence A key use of the sequence information from the canonical model organisms, such as Drosophila, will be to help interpret the sequence of the human genome.

Using Drosophila as a model organism, his aims are to identify the gene regulatory networks that modulate neural stem cell properties during the course of development.

In particular we are interested to unravel the mechanisms that ensure the maintenance of the apical membrane when exposed to physical stress, e. g. during morphogenesis of epithelial tissues, or when exposed to light stress in photoreceptor cells, using Drosophila and zebrafish as model organisms.

Sten Grillner has elucidated basic principles of neural circuit organization and function that control vertebrate locomotion using lamprey as a model organism.

We address these questions by combining genetics with live imaging, quantitative image analysis and biophysical approaches using the fruit fly Drosophila melanogaster as a model organism.

Professor Horvitz had already made major contributions to understanding neural development using C. elegans as a simple model organism.

Enriched by the rapid evolution of these technologies, TEFOR - TACGene has developed a solid expertise in the design, production and use of TALE - N and CRISPR / Cas9 systems, both for its own research projects in cultured cells and in collaboration, in many model organisms, including the rat, zebrafish, Drosophila, and Xenopus as part of the National Infrastructure in Biology and Health TEFOR supported by Investissement d'Avenir programme (2012 - 2019).