Sentences with phrase «used at trial by»

At the same time BMO would be prepared to circulate a Summation - style database of relevant documents which could also be used at trial by those who so desired.

Not exact matches

These risks and uncertainties include, among others: the unfavorable outcome of litigation, including so - called «Paragraph IV» litigation and other patent litigation, related to any of our products or products using our proprietary technologies, which may lead to competition from generic drug manufacturers; data from clinical trials may be interpreted by the FDA in different ways than we interpret it; the FDA may not agree with our regulatory approval strategies or components of our filings for our products, including our clinical trial designs, conduct and methodologies and, for ALKS 5461, evidence of efficacy and adequacy of bridging to buprenorphine; clinical development activities may not be completed on time or at all; the results of our clinical development activities may not be positive, or predictive of real - world results or of results in subsequent clinical trials; regulatory submissions may not occur or be submitted in a timely manner; the company and its licensees may not be able to continue to successfully commercialize their products; there may be a reduction in payment rate or reimbursement for the company's products or an increase in the company's financial obligations to governmental payers; the FDA or regulatory authorities outside the U.S. may make adverse decisions regarding the company's products; the company's products may prove difficult to manufacture, be precluded from commercialization by the proprietary rights of third parties, or have unintended side effects, adverse reactions or incidents of misuse; and those risks and uncertainties described under the heading «Risk Factors» in the company's most recent Annual Report on Form 10 - K and in subsequent filings made by the company with the U.S. Securities and Exchange Commission («SEC»), which are available on the SEC's website at www.sec.gov.

It's probably not going to be possible to have a jury of people that have never heard of the bands, that have never heard the music, but the real question is, even with that understanding, can they only focus on the evidence that's being presented by the parties at trial and only use that evidence and nothing from their own life experience outside of the courtroom to make that decision?

These are (1) the right to have a lawyer present to advise him either prior to questioning or during it; (2) if he can not afford a lawyer, the right to have one appointed by the state to counsel with him prior to or during the making of a statement; (3) the right to remain silent and not make any statement at all, knowing that any statement he does make may be used against him at his trial.

«In attending meetings, this singularity was a trial to me, and more especially at this time, as white hats were used by some who were fond of following the changeable modes of dress, and as some friends, who knew not from what motives I wore it, grew shy of me, I felt my way for a time shut up in the exercise of the ministry.

In this randomized controlled trial, the use of peer counselors for breastfeeding mothers of premature infants increased breastfeeding duration, measured by the infants receiving any breast milk at 12 weeks.

A prosecutor argued at the bribery trial of former top Cuomo aide Joe Percoco that he proved his guilt by quoting from the mob drama «The Sopranos» with the now infamous use of the word «ziti» to indicate bribes.

At his 2015 trial, evidence showed that Silver, 73, sponsored state grants to mesothelioma researcher Dr. Robert Taub, who helped generate fees for Silver by referring patients to his law firm, and backed legislation favored by developers who used a tax law firm affiliated with Silver.

Percoco was off the state payroll but used his Manhattan office — near the governor's in the executive chamber — to make calls on 68 days during that period, according to evidence submitted by federal prosecutors at the trial.

Audio recordings released by the US Attorney's office at the corruption trial of Senator Dean Skelos aim to show that the Senate Leader and his son colluded to use Skelo's official position to help his son get employment.

Late last year, federal prosecutors said they may introduce evidence at trial to show that Percoco «threatened at least four New York State employees... who were considering leaving their current jobs or State service entirely, by claiming that [he] would use his extensive influence... prevent them from finding future employment.»

Greensboro, North Carolina (CNN)- Prosecutors wrapped up their case in the John Edwards corruption trial Thursday, detailing hundreds of thousands of dollars in expenses used by his former mistress, whose concealment during Edwards» failed presidential run remains at the heart of the scandal.

In the course of the trial, the prosecution tendered in a post-mortem report of the MP, Forensic DNA Report, Blood stained T - shirt of Asiedu, a knife used by Asiedu, the three iPhones of the deceased, Asiedu's pair of slippers which he left at the crime scene, his prison records, and radiology report determining his age, his medical report, all as evidence to prosecute him.

Dr Sheldon Stone presented the findings from a major three - year trial led by researchers at University College London, in partnership with the Health Protection Agency, showing that giving one - to - one feedback to healthcare workers makes them twice as likely to clean their hands or use soap.

The movement on the measures comes amid a federal trial over the department's use of stop and frisk, and it follows a series of stories by The Associated Press that revealed how city police systematically listened in on sermons, hung out at cafes and other public places, infiltrated colleges and photographed people as part of a broad effort to prevent terrorist attacks.

Audio recordings released by the U.S. Attorney's office at the corruption trial of State Senator Dean Skelos of Long Island aim to show that the Senate Leader and his son colluded to use Skelos» official position to help his son get employment, in what turned out to be a succession of no show jobs.

The strains that consumed oil fastest were selected for further trials, and in 1998, the team used the top performers in an experiment sponsored by the Washington State Department of Transportation at a maintenance yard in Bellingham.

A statin drug commonly used to lower cholesterol is not effective in reducing the number and severity of flare ups from chronic obstructive pulmonary disease (COPD), according to the results of a large multicenter clinical trial designed and directed by Gerard J. Criner, MD, Director of Pulmonary and Critical Care Medicine at Temple University Hospital in Philadelphia, PA..

A large Australian trial showing that daily use of nicotinamide, a form of vitamin B3, for 12 months reduced the incidence of new non-melanoma skin cancers by 23 % in patients at high risk for skin cancer

The future challenges of this line of research, started through an undergraduate degree final project by Carlos Aguado in the Grupo de Computación Evolutiva y Redes Neuronales (EVANNAI - Evolutionary Computation and Neural Networks Group) at UC3M, include carrying out clinical trials using this technology, in addition to developing programs that help rehabilitate the other four movement of the shoulder: flexing, extension, internal rotation and external rotation.

But cognitive studies suggest primates use tools mainly by trial and error, whereas humans understand the principles at work — such as gravity and force — and exploit them to make novel tools.

Many patients and physicians assume that the safety and effectiveness of newly approved drugs is well understood by the federal Food and Drug Administration (FDA)-- but a new study by researchers at Yale School of Medicine shows that the clinical trials used by the FDA to approve new drugs between 2005 and 2012 vary widely in their thoroughness.

A drug used to treat men with late - stage prostate cancer proved effective in stemming progression of the disease in research participants who had not yet received chemotherapy and extended their survival, according to results from a multi-national Phase III clinical trial led by the Knight Cancer Institute at Oregon Health & Science University (OHSU).

The proposed clinical trial, in which researchers would use CRISPR to engineer immune cells to fight cancer, won approval from the Recombinant DNA Advisory Committee (RAC) at the U.S. National Institutes of Health, a panel that has traditionally vetted the safety and ethics of gene therapy trials funded by the U.S. government and others.

Because the anti-retroviral drug maraviroc has already been approved by the U.S. Food and Drug Administration and has been shown safe for long term, oral use, it could be tested in clinical trials sooner rather than later, says Aleksander Popel, Ph.D., a professor in the Department of Biomedical Engineering at the Johns Hopkins University School of Medicine and member of the Johns Hopkins Kimmel Cancer Center.

«Recruitment for clinical trials in children with autism is one of the biggest challenges we face in studying potential treatments, and we found that process to be accelerated and streamlined by using existing online communities for enrollment,» said lead author Stephen Bent, associate professor of medicine at UCSF.

New results from a clinical trial involving more than 900 military veterans at high risk for keratinocyte carcinoma skin cancer provides evidence that using the generic skin cream fluorouacil 5 percent for two to four weeks may reduce the risk of a squamous cell carcinoma (SCC) needing surgery by 75 percent within a year.

Using a novel synthetic platform for creating vaccines originally developed in the laboratory of David Weiner, PhD, a professor of Pathology and Laboratory Medicine from the Perelman School of Medicine at the University of Pennsylvania, a team led by his colleagues at the Johns Hopkins University School of Medicine, has successfully eradicated precancerous cervical lesions in nearly half of the women who received the investigational vaccine in a clinical trial.

This clinical trial is the culmination of long - standing research led by Professor John Greenwood at the UCL Institute of Ophthalmology showing the potential therapeutic benefits of using statins to treat autoimmune diseases such as multiple sclerosis and uveitis.

The fuels have successfully passed all trials — even delivering more thrust per gallon — and have now entered regular commercial use in the U.S. and Europe, promising to cut CO2 emissions by 80 percent, albeit at a premium price.

The white paper recommends that practitioners follow relevant guidance documents and that deviation from consensus recommendations should be supported by clinical studies or pursued in the setting of a clinical trial approved by an institutional review board; that practitioners receive training in a new procedure before beginning its practice, that the training should include a practical, «hands - on» component and that all team members directly involved with the radiation therapy decisions should participate in at least five proctored cases before performing similar procedures independently; and that professional societies should accelerate the generation of new or updated guidance documents for the following disease sites and techniques: skin, central nervous system, gastrointestinal, lung or endobronchial and esophagus, and, while outside the charge of this panel, assess the need for updated guidance documents for accelerated partial breast irradiation using electronic brachytherapy.

An earlier form of the vaccine was used in the DarDar Trial, a seven - year study in Tanzania sponsored by the U.S. National Institutes of Health involving patients with HIV infection who at birth had received BCG, the current tuberculosis vaccine.

The STAR trial was conducted under controlled conditions, while the Penn study takes the next step by looking at outcomes in post-approval clinical use of the device.

They estimate that using these algorithms to predict outcomes could allow a drug sponsor to reduce the size of the trial by at least 20 % and save as much as $ 6 million in a large phase III trial.

A research team led by Gianluca Maddalo (KTH), involving several researchers at SciLifeLab, has discovered that melanoma resistance against BRAF and Hsp90 inhibitors can be overcome by implementing the current BRAF / MEK inhibitors therapy with a CDK2 inhibitor, dinaciclib, already used in clinical trials.

The products used in the trial were tested in the U.S. prior to the launch of the study in Uganda and were developed by the Vaccine Research Center (VRC) at the National Institute of Allergy and Infectious Diseases (NIAID).

Working in the Integrative mathematical oncology department, he is using the mathematical model to test treatment plans being developed by clinicians at the center before they are applied to patients during clinical trials.

There was no proof it would help (trials are under way at Stanford, partly sponsored by the SMA Foundation), but it had been safely used before on kids with sickle - cell anemia.

PHILADELPHIA - Using a novel synthetic platform for creating vaccines originally developed in the laboratory of David Weiner, PhD, a professor of Pathology and Laboratory Medicine from the Perelman School of Medicine at the University of Pennsylvania, a team led by his colleagues at the Johns Hopkins University School of Medicine, has successfully eradicated precancerous cervical lesions in nearly half of the women who received the investigational vaccine in a clinical trial.

Stress resistance has not been assessed however and so the biological relevance of this finding is currently unknown.32 Several IER trials (75 - 85 % ER on restricted days) in overweight / obese populations have reported reductions in various markers of oxidative stress 37, 41, which in one study was accompanied by a complementary increase in the anti-oxidant uric acid.37 In a direct comparison of IER (75 % ER for two days / week) and CER, both ER strategies displayed equal efficacy in reducing levels of fast - acting advanced oxidation protein products (AOPP) after six months, which displayed a tendency to occur earlier (i.e. at three months) in the IER group.41 Levels of slow - acting (i.e. long term) AOPP tended to decrease in the IER group and increase in the CER group which the authors proposed may have resulted from IER - induced activation of autophagy, a key homeostatic cellular process in which dysfunctional or unnecessary cellular proteins are degraded and recycled.41 On the other hand, a follow - up study using similar IER / CER protocols demonstrated comparable reductions in AOPP in both groups after three months.48 Summary and Future Research Directions

The Gold membership on the other hand comes with all the benefits of silver membership, plus a A benefit of a topping of all listings and searches to enable your profile to be seen by even more members.You also get to email free members, who can also reply back.The membership allows you a seven - day trial at $ 9.95, and then $ 34.95 monthly.Both memberships come with a Three - Month Guarantee, within which period if you do not find your match, the site gives you an extra free 3 month period to access their services.Payment types and methods accepted in the site include phone, credit and debit cards.Rates for women who use the site are usually lower than that of the men.

He secures the throne in trial - by - combat at a mythic waterfall, defeating M'Baku (Winston Duke), the chief of the Jabaris, the only tribe in the kingdom that shunned the use of vibranium.

In a randomized controlled trial conducted at the United States Military Academy (West Point), the authors find that unrestricted laptop use reduces students» exam scores by 0.18 standard deviations relative to students for whom laptop use was prohibited; tablets reduce scores by 0.17 standard deviations (see figure).

Students Matter's policy recommendations were developed using the overwhelming evidence presented at trial, through conversations with policy experts, superintendents, teachers and parents on the ground, as well as by surveying the successful teacher employment laws already implemented in other states.

Marion Superior Court Judge Michael Keele decided not to halt the program because arguments against it — namely, the vouchers violate the separation of church and state by using public money to fund religious schools — are unlikely to succeed at trial.

The blunder was initially spotted by a teacher at one of 700 schools that was carrying out an official trial of the test, using the paper that was to be taken by pupils around England.

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8.4 We may terminate your licence to use any free trial software program at any time, by giving you written notice of termination or deactivating the relevant software program.

In hunting trials, which used to be required by many kennel clubs for championships, Glens were disqualified if they sounded at the quarry.