The mechanism
used by Notch to regulate Myc in B cells is distinct from the mechanism used in other cell types, such as T cells, where Notch also regulates Myc.
Not exact matches
A study done earlier in the year
by the same company revealed that finding top -
notch people is even harder than it
used to be.
Dijon mustard is definitely the most popular mustard
used for your typical honey mustard dressing, but you can certainly tone it down a
notch by experimenting with other mustards.
I love the flavor of Korean Beef and have been making a recipe
using ground beef instead of sliced sirloin for awhile, but I decided to take it up a
notch by adding broccoli to it to combine tow of my favorite dishes — Beef & Broccoli and Korean Beef.
And then, she kicks it up a
notch by using the same spice mixture to make, wait for it, wait for it, SPECULOOS WAFFLES!!
The fresh herbs kick it up a
notch too and I'm intrigued
by the
use of maple syrup!
I only
use top
notch quality olive oil for hummus, so it's kind of a shame to lose its flavor
by blending it in.
Karen Jagoda has what looks to be another top -
notch Digital Politics Show today, broadcast live at 3 PM Eastern: With one month to go until Election Day, the topic today is how online ads and mobile apps are being
used in the ground game and how campaign narratives are being shaped
by dirty...
By using a different shaped
notch / lug pair for each symbol
used as a label, we can convert labelled prototiles into ordinary ones of more complicated shapes.
For example the researchers
used the CRE - ERT2 mouse model validated at the ICS, in which Cre function is controlled
by the promoter of Atypical
Notch ligand Delta - like homologue1 (Dlk1) under Tamoxifen activation, a skin fibroblast marker, to carry out temporal and tissue specific inactivation of key genes involved in skin fibroblast diversity.
This recipe kicks it up a
notch by making single -
use sugar scrub cubes that cleanse, exfoliate, and soften skin all in one easy step.
While I have lost 7 - 8 lbs, my fluid levels are OK - I am properly hydrated, I exercise every other day (27 minutes on an elliptical and another 15 on the total gym) it would be nice to determine fat loss more accurately than
by using a scale or the
notches on my belt: >) Any suggestions would be appreciated.
Furthermore, we don't fill our water with top -
notch pharmaceutical grade fluoride; we
use an industrial
by - product called hydrofluorosilicic acid.
The fresh herbs kick it up a
notch too and I'm intrigued
by the
use of maple syrup!
Velvet is
used more creatively this season; turn it up a
notch by buying a pair of velvet knee high boots.
I've never
used anything actually
by smashbox, but I know it is supposed to be top
notch.
The look can be achieved
using actual shiplap that has a special
notch aligning with the next board to form a water - tight seal, tongue and groove which
uses interlocking wood pieces to add strength, or
by simply nailing wooden or MDF boards to the wall.
The overall ease of
use offered
by the site is top
notch and one can also engage in real time messaging and even share photos privately as well.
Burdened
by the high cost of living and student debts, more and more people are
using side hustles to earn extra income; on the other hand, attractive young women are taking things up a
notch,
by becoming sugar babies.
Why settle for cheap, third class services on Backpage when you can get top
notch stuff
by using the best dating apps in America?
But like Abrams did on «Star Trek,» Whedon has stepped up his game in a major way: the action is clear and coherent, the pacing is tight (it's 140 minutes long, but flies
by) and the technical contributions are top -
notch across the board, from the Bond - movie production design of James Chinlund («The Fountain «-RRB- and the razor - sharp cutting of Jeffrey Ford («Public Enemies «-RRB- and Lisa Lassek («Cabin In The Woods») to Seamus McGarvey «s bright cinematography and Alan Silvestri's firmly listenable score (although the latter could, it should be said,
use a more distinctive theme).
Meanwhile, the level of criminals have been upgraded a
notch when psychotic billionaire Norman Osborn (Dafoe, The Boondock Saints), father of Peter's roommate Harry (Franco, City
by the Sea), takes to terrorizing his enemies and the citizens of New York
using a high - tech glider and suit under the moniker of the Green Goblin.
The payoff for
using portfolios becomes concrete when students discover they can earn college credit and, in some cases, skip a freshman writing class
by creating a top
notch writing portfolio while they are still in high school.
Behind the upright façade is a cabin marked
by its top -
notch materials and dash layout — even the iDrive infotainment system, a once despised setup, is easy to
use.
Roadside Assistance for 1 Year * 174 Point Inspection * Transferable Warranty * Vehicle History * Powertrain Limited Warranty: 84 Month / 100, 000 Mile (whichever comes first) from original in - service dateHere at Riverhead Toyota, we are not only passionate about our new and
used Toyota model lineup, but we are extremely dedicated to providing top -
notch customer service not only to Riverhead, but also many surrounding areas like Shirley NY, Hampton Bays, East Hampton, Smithtown, and both the entire North and South Forks customers as well.31 / 34 Highway / City MPG Awards: * 2016 IIHS Top Safety Pick + Beyond simply selling new cars, our dealership is also known for giving Toyota models a second chance on the road
by carrying an excellent selection of
used cars as well.
That throttle response is kicked up a
notch by using the shifter to switch the transmission into «S» mode.
The quality of trim materials has improved
by several
notches over those of the ASX or Outlander, but there is still a large amount of dark plastic, and lesser -
used switchgear has been shunted into a hard - to - see block between the steering wheel and the door.
It has never been so easy to achieve high academic goals
by using the services of our top
notch writing company.
Take this up a
notch by using the comment option on Amazon to thank every person who has posted a book review.
Using an excellent online paper writing service provided
by our company is a great opportunity for you to get top -
notch academic papers.
The crew over at xda - developers were the ones responsible to turn things up
by a
notch, where they
used a recompiled version of Tiamat 1.4.2 while cranking out an extra 100 MHz to touch the 1.6 GHz mark.
We've been
using the Switch 10 on long - haul trans - Atlantic flights to catch up on Boardwalk Empire and the 720p files have looked top
notch to us, only occasionally ruined
by a sunburnt face reflection staring back.
Excellent Technicians: The quality technicians are applauded for completing the job
by the deadline while
using the best repair techniques and top -
notch building materials.
Our creative take on grooming raises the bar
by offering top -
notch services
using the most advanced grooming equipment.
To kick your training program up a
notch, achieve 90 percent retention
by providing opportunities for the recently trained to teach someone else and immediately begin
using their newly acquired knowledge and skills.
By implementing several strategies, credit card sign - up bonus and bonus miles via referral I was able to acquire more than 700,000 miles and points without flying.We
used some of these miles and points to travel for almost free to destinations like Washington D.C, Myrtle beach, Miami, NYC, Baltimore, Cancun and the highlight of this year was our 10 days Trip to Europe (Spain and France) which costed me barely $ 500 (airfare + lodging) for two people while flying business class on US Air (more details in next week posts) and staying at some top -
notch five star hotels in the best of the locations.
The only way to fix this is
by using the games unbalanced difficulty selection: ramp it up to the highest and you'll find it hard to place 15th on the grid in your Caterham, which is far more realistic, but drop the difficulty level down just one
notch and you'll suddenly find yourself winning races again with ease.
By far the biggest improvement is the
use of weapons, as the targeting system is top
notch.
The game
uses spatial audio tech so you can determine where the ball is
by sound, and there's also a top
notch soundtrack and audio - reactive visuals to boot.
Fear Effect's original charm was that it took the fixed camera angles and gameplay from Resident Evil and bumped the presentation and story up a
notch by using FMV for backgrounds instead of still images.
Stella, surely the university's best - known contribution to the art world,
uses notches in opposite corners to shape the canvas and,
by extension, its successive stripes.
Nonono, not the policy statement, well there is that, but a bunch of resources that ACS has put out there a climate science tool kit for folks to learn from and
use, put together
by a top
notch working group with support from ACS leadership.
Australia has top
notch direct normal irradiance (DNI) the solar resource
used by CST, but development has been stymied
by Australia's renewable policy that does not factor in the extra value of solar energy that can be delivered on demand, day or night.
The Utility MACT requires plant -
by - plant controls to greatly reduce air emissions of mercury
using attainable but top -
notch technology.
Find high quality Mentor renters insurance rates
by using our simple free service and get connected to all of the top
notch protection you need for you and your loved ones at a reasonable premium.
However, this feature is mainly for developers, who can
use it to test how their apps will interact with
notches, making sure crucial bits of information don't get hidden
by accident.
But no, the
notch is here to stay and Google's Android software will be accommodating it
by design in a future update (the P20 Pro
uses the company's EMUI 8.1 re-skin as a solution - more on the software later).
The Huawei P20 Pro - along with the standard Huawei P20 - is also the first Huawei phone with a
notch, the display cut - out made famous
by the iPhone X. Apple's excuse for the
notch is it is required for all the tech
used for the phone's face unlock feature: a normal camera, an IR camera, a dot projector, proximity sensor and more.
Our research has shown that the space occupied
by the
notch typically goes unused in standard
use.
On the other hand, the OnePlus 3T, OnePlus 5, Samsung Galaxy S7 Edge or even the new Galaxy S8 might be having top -
notch hardware specs, but the fact that they weren't built
by the same team makes a huge difference in the overall experience of
using them.