Sentences with phrase «used electron microscopy»

The lab of Georgios Skiniotis, also at the LSI, used electron microscopy to show how NS1 associates with membranes of the infected cell, which the researchers suspected would be associated with both virus replication and immune evasion.

The team used electron microscopy and other surface - and bulk - sensitive tools, located in EMSL, to probe the structural evolution of active materials.

The researchers used electron microscopy and other imaging techniques to view thousands of cells from the liver tissue of lean and obese mice.

Neurobiologist Bernd Knoll at the University of Tubingen in Germany and his collaborators used electron microscopy to picture this neuron's cobweb - like cytoskeleton (its interior scaffolding).

To gain more insights into this highly specific degradation pattern, Qinghua Zhou et al. used electron microscopy and tomography to study sperm mitochondria (or paternal mitochondria) in Caenorhabditis elegans, a type of roundworm, during early stages of development.

The researchers used an ion beam to slice off thin sections from the samples, and they used electron microscopy techniques to image the samples and perform elemental analyses.

The researchers then used electron microscopy to visualize their necklaces, shown above.

A friend of mine relates how, when he was in college, he was using electron microscopy to look at subcellular organelles.

The research involved the study of laboratory earthquakes — high - pressure earthquakes as well as high - speed ones — using electron microscopy in friction and faulting experiments.

However, when they tried to create high - magnification images of the interaction using electron microscopy, they were surprised that they could not find any intact VLPs.

«Using electron microscopy, we observed lipid droplet accumulation in glia before obvious symptoms of neurodegeneration,» Liu said.

Using electron microscopy tools combined with analytical spectroscopy techniques, the researchers were able to examine the surface of bioprocessed Martian regolith simulants in detail.

Using electron microscopy to look at thousands of ultrathin brain slices taken from awake and sleeping mice, they found that after sleep, the size of most synapses — specifically, the surface area where two neurons touch each other — shrank by about 18 percent.

A similar combination of computational modeling based on quantum mechanics, molecular dynamics, and direct observation using electron microscopy «can probably be applied to many systems,» Buehler says.

Here we develop a semi-automated pipeline using electron microscopy to reconstruct a connectome, containing 379 neurons and 8,637 chemical synaptic contacts, within the Drosophila optic medulla.

The goal of the FlyEM Project is to produce and analyze connectomes of behaviorally - relevant neural circuits in the entire Drosophila nervous system using electron microscopy.

Professor Deborah Smith, Pro-Vice-Chancellor for Research, added: «Professor Gai has pushed the boundaries of scientific research using electron microscopy.

New method to visualise chromatin organisation in 3D within a cell nucleus (purple): chromatin is coated with a metal cast and imaged using electron microscopy (EM).

In a ground - breaking collaborative research project using electron microscopy, circular dichroism and X-ray fiber diffraction, researchers at the University of Sussex and TauRx Pharmaceuticals have succeeded in showing that the truncated fragment can be made to assemble into PHFs in the test tube (https://doi.org/10.1016/j.jmb.2017.09.007).

Though Gonen has published widely on the structure and regulation of membrane proteins — using electron microscopy and X-ray crystallography — continued efforts are on pause for now in favor of developing new methods for studying them, such as MicroED.

We aim to close this gap by implementing a novel assay to simultaneously assess the integrity of the axonal cytoskeletal structure (using electron microscopy) and a functional (physiological) correlate of healthy cytoskeletal structure, namely active axon transport, within individual RGC axons at an early stage of experimental glaucoma.

Scheller went on to use electron microscopy to pin point the location of v - and t - SNARE proteins on vesicles and the pre-synaptic membrane.

To continue this work, he moved to the Walz lab as a post-doctoral fellow, where he completed the first atomic resolution structure of a mammalian membrane protein, aquaporin - 0, using electron microscopy.

Gonen completed his PhD by commuting — up to 5 times in one year — between Auckland and Boston, MA, where he worked with Tom Walz at Harvard Medical School to complete his studies of MP20 using electron microscopy.

Using electron microscopy instrumentation and methods he developed, Yimei Zhu has been investigating this question for the past 30 years.

Using electron microscopy on the thermophilic AOM cultures this idea was confirmed.

Not exact matches

A detailed view of TRPM8's structure, obtained using cryo - electron microscopy, was published by a different research group online December 7 in Science.

Frank of Columbia University, Henderson of the MRC Laboratory of Molecular Biology in Cambridge, England and Jacques Dubochet of the University of Lausanne in Switzerland were named Nobel laureates for significant discoveries that led to the development and use of cryo - electron microscopy to produce close - up, three - dimensional views of biomolecules.

Pan, Schweitzer and their team used both scanning and transmission electron microscopy to get microscopic details of the feather's surface and its internal structure.

A pioneer of modern cell biology used cell fractionation and electron microscopy to describe subcellular structures.

Five years ago, using a lower - resolution form of electron microscopy in which the protein is visualized in the presence of negative stain, Whelan's team was able to detect at low resolution a structure that looked like a doughnut with three globular domains.

Study co-author Dr Carolina Loch says this was the first time the enamel ultrastructure of fur seals and sea lions, as well as the extinct walrus Pelagiarctos, was studied using scanning electron microscopy.

Using cryo - electron microscopy — which involves freezing, then imaging a sample — the researchers have taken thousands of photos of their current target, a protein complex involved in breaking down other, unwanted proteins.

«Understanding how the enzyme actually works requires the knowledge of its three dimensional molecular structure at the atomic level,» said Dr. Mueller, principal investigator for the study that used cryo - electron microscopy (cryo - EM) to reveal the enzyme at near atomic resolution.

The new 3 - D structure, which was obtained using X-ray crystallography and electron microscopy, revealed that the outer surface of the Zika NS1 protein has substantially different electrical - charge properties than those of other flaviviruses — indicating it may interact differently with the members of an infected person's immune system.

The researchers used a number of methods, including fluorescence and electron microscopy, in collaboration with Dr. Eugenia Klein of the Institute's Microscopy Unit; a unique system in Prof. Alon's lab for simulating blood vessels in a test tube; and in vivo imaging with Prof. Sussan Nourshargh of Queen Mary University of London.

The traditional methods used in materials science analysis, like high - powered electron microscopy and spectroscopy, do not combine chemical insights with the spatial resolution of IR imaging, the researchers said, so they can only provide average chemical measurements.

Because they are so small, multiple testing methods are used, including cross-polarized light microscopy, scanning electron microscopy and PCR testing of the DNA of larvae in the water sample.

To probe further, Bello and her colleagues examined the remains using two types of microscopy: scanning electron and focus variation microscopy.

SAY FREEZE Scientists used an imaging technique called cryo - electron microscopy to snap the first close - ups of lithium dendrites, revealing them as long, needlelike crystals.

Hochstein and her collaborators from MSU, the University of California, Los Angeles, and the Max Planck Institute of Biochemistry in Germany learned more about the structure of the Acidianus virus by using a combination of cryo - electron microscopy and X-ray crystallography.

Using transmission electron microscopy, EPFL scientists have examined a slice from a meteorite that contains large diamonds formed at high pressure.

The researchers studied the diamond samples using a combination of advanced transmission electron microscopy techniques at EPFL's Interdisciplinary Centre for Electron Micelectron microscopy techniques at EPFL's Interdisciplinary Centre for Electron MicElectron Microscopy.

This achievement has been made possible by using high - resolution cryo - electron microscopy, a technique brought to the CNIO thanks to Óscar Llorca, director of the Structural Biology Programme and lead author on the paper published in Nature Communications.

Using transmission electron microscopy, the team imaged individual tubes and sized up the kinks.

Previously, Chueh and other scientists have used transmission electron microscopy (TEM) to study working batteries at the nanoscale.

Scientists used techniques such as scanning electron microscopy and x-ray imaging to investigate species» bodies and feeding mechanisms.

Researchers used scanning electron microscopy to characterize the surface structure of the scutes.

Acquiring images using modern techniques such as light sheet fluorescence, confocal, or electron microscopy creates a significant data stream.

By using thousands of images, they reconstructed a high - resolution cryo - electron microscopy structure of the Zika virus.