Sentences with phrase «used human skin cells»

«We used human skin cells that we obtained from patients affected with ALS and converted them into neurons via a technology called induced pluripotent stem cell production,» she explains.

To make the HSCs, the Harvard group used human skin cells to create induced pluripotent stem cells (iPSCs), adult cells researchers genetically reprogram to an embryonic - stem - cell state, where they can grow into any kind of cell.

Not exact matches

In a rare appearance Dr. Chandan Sen, Director, OSU Center for Regenerative Medicine & Cell - Based Therapies will explain how this breakthrough came about and how the technology is leading to other medical discoveries and how the principle can be used to generate any tissue out of skin or fat which is abundant in human body.

Unlike the controversial method of tissue harvesting that requires some human embryos to be destroyed, the new cloning technique can use a patient's own skin cells — combined with an unfertilized human egg — to create tissue with a DNA match.

Scientists looking for new methods to make human tissue have successfully used cloning technology to create embryonic stem cells from skin cells.

Using viral gene insertion and regulatory proteins, researchers turned adult human skin cells directly into adult human blood cells, without first returning them to a fully pluripotent state.

Anand and his colleague Susan McKay started with human skin cells, which they turned into induced pluripotent stem cells (iPSCs) using a tried - and - tested method.

Using a mathematical model known as the Ising model, invented to describe phase transitions in statistical physics, such as how a substance changes from liquid to gas, the Johns Hopkins researchers calculated the probability distribution of methylation along the genome in several different human cell types, including normal and cancerous colon, lung and liver cells, as well as brain, skin, blood and embryonic stem cells.

«Our results demonstrate for the first time that human adult skin cells can be used to efficiently and rapidly generate functional pancreatic cells that behave similar to human beta cells,» says Matthias Hebrok, PhD, director of the Diabetes Center at UCSF and a co-senior author on the study.

In May 2013, Mitalipov was the first scientist in the world to demonstrate the successful use of somatic cell nuclear transfer, or SCNT, to produce human embryonic stem cells from an individual's skin cell.

Human epidermal equivalents representing different types of skin could also be grown, depending on the source of the stem cells used, and could thus be tailored to study a range of skin conditions and sensitivities in different populations.»

A California company reported today that it has, for the first time, cloned human embryos using DNA from adult skin cells.

The scientist tested their set - up using frozen human skin cells, segments of pig heart tissue, and sections of pig arteries in volumes almost 20 times larger than previously attempted samples.

One uses primary hepatocytes obtained from livers donated for transplant; the second uses stem cells derived from human skin samples and guided into hepatocyte - like cells, Bhatia says.

The study carried out at the University of Eastern Finland used the induced pluripotent stem cell technology, which enables the generation of pluripotent stem cells from human skin fibroblasts.

For the new study, the team used a cell - reprogramming technique (similar to those used to reprogram skin cells into stem cells) to generate human DRG - type sensory neurons from ordinary skin cells called fibroblasts.

«It appeared we wouldn't be able to create enough human OPCs for widespread therapeutic use, so we began to wonder if we could create them directly from skin cells.»

Using a process called cellular reprogramming, the researchers take a patient's skin cells, convert them into so - called induced pluripotent stem (iPS) cells, which can differentiate into all the cells within the human body.

Both teams successfully used these to reprogramme skin cells in a lab dish into cells resembling embryonic stem cells, which have the ability to turn into any tissue of the human body.

At the time, his varied interests — in the use of skin cell culture to treat burns, in human tissue cultures, and in biopharmaceutical production — led him to do his final year, 6 - month project on culture in a bioreactor.

Humans have many cell types - nerve cells, blood cells, skin cells, to name a few - and while each cell contains the same genetic instructions, different parts of the genetic information are used to produce proteins in each type of cell.

Gladstone scientist Dr. Sheng Ding has exposed more chameleon - like qualities of the human skin cell, using chemical cocktails to turn skin cells into fully functional brain, heart, liver, and insulin - producing pancreas cells.

The advantages of this approach began to emerge in 2011, when Dr. Ding announced that he had used his «chemical reprogramming» method to convert human skin cells into brain cells.

Recently, his lab used induced pluripotent stem (iPS) cells — adult cells made to act like embryonic stem cells — made from skin cells of patients carrying apoE4, or other mutations related to Alzheimer's, to study their effects on the development, survival, and degeneration of human neurons.

Globs of human fat removed during liposuction conceal versatile cells that are more quickly and easily coaxed to become induced pluripotent stem cells, or iPS cells, than are the skin cells most often used by researchers, according to a new study from Stanford's School of Medicine.

Strengthening the link between Zika virus and microcephaly, scientists at UC San Francisco have discovered that a protein the virus uses to infect skin cells and cause a rash is present also in stem cells of the developing human brain and retina.

Researchers at the University of North Carolina at Chapel Hill School of Medicine have transformed cells from human skin into cells that produce insulin, the hormone used to treat diabetes.

Yet this study brings us tantalisingly close to using skin cells to grow many different types of human tissues.

Yamanaka's group used human adult skin cells and induced them to become iPS cells by having them produce the same protein factors that the mouse iPS cells had.

Human skin cells have also been directly converted into neurons that can be used to study and find treatments for diseases in the brain, as well as liver cells and insulin - producing cells of the pancreas.

In the Science study, led by first author Nan Cao, PhD, a postdoctoral fellow in Ding's lab, the researchers used a cocktail of nine chemicals to change human skin cells into beating heart cells.

In the Science study, Ding's team used trial and error to find a combination of chemicals that could induce human skin cells to turn into multipotent stem cells, and then into cardiomyocytes.

Using Gladstone's unique expertise, the scientists then used induced pluripotent stem cells (iPSCs), generated from adult human skin cells, to create a type of beating heart cell known as cardiomyocytes.

Only a year after he produced the first iPS cells from adult mouse skin cells, Yamanaka generated iPS cells from adult human skin cells, employing human versions of the same four genes that he had used in the mouse work.

Several trials using human cells have shown it to have protective effects on the skin.

Our writer investigates the benefits of using skin care products that contain plant - derived stem cells — and non-embryonic human cells extracted from consenting egg donors (seriously).

Currently, her lab is focused on finding drugs suitable for eliminating mammary cancer and ocular herpevirus infections in small companion animals, and evaluating the effectiveness of stem cell therapies for treating skin wounds in horses — all of which may also be used in humans and other animals.