Sentences with phrase «used in cell metabolism»

Macromolecules such as starch, cellulose or proteins can not be rapidly taken up by cells and must be broken into their smaller units before they can be used in cell metabolism.

Not exact matches

For example, cancer cells tend to use glycolysis in the cell cytoplasm in their metabolism, an ancient system, whereas healthy cells use oxidation - phosphorylation.
In a nutshell, the metabolism refers to the essential biochemical reactions (such as digestion and production of hormones) that regulate how our cells use and store energy.
Using an MRI technique that is sensitive to certain byproducts of cell metabolism, including levels of glucose and acidity, University of Iowa researchers discovered previously unrecognized differences in the brains of patients with bipolar disorder.
They all use RNA molecules as messengers to transfer the information from DNA to cellular factories called ribosomes, which then build proteins, which in turn drive our metabolisms and form the structures of our cells.
The metabolism of bone cells determines how much sugar they use; if the bone cells consume more sugar than normal, this can lower the glucose level in the blood.
Mitochondria are found in cells and they use oxygen to produce energy in a process called oxidative metabolism.
In a study presented in the featured clinical investigation article of the November issue of The Journal of Nuclear Medicine, they used 18F - fluorodeoxyglucose (FDG) PET / CT imaging to show that the amount of cell - free tumor DNA circulating in the bloodstream correlates with tumor metabolism (linked to cancer aggressiveness), not tumor burden (amount of cancer in the bodyIn a study presented in the featured clinical investigation article of the November issue of The Journal of Nuclear Medicine, they used 18F - fluorodeoxyglucose (FDG) PET / CT imaging to show that the amount of cell - free tumor DNA circulating in the bloodstream correlates with tumor metabolism (linked to cancer aggressiveness), not tumor burden (amount of cancer in the bodyin the featured clinical investigation article of the November issue of The Journal of Nuclear Medicine, they used 18F - fluorodeoxyglucose (FDG) PET / CT imaging to show that the amount of cell - free tumor DNA circulating in the bloodstream correlates with tumor metabolism (linked to cancer aggressiveness), not tumor burden (amount of cancer in the bodyin the bloodstream correlates with tumor metabolism (linked to cancer aggressiveness), not tumor burden (amount of cancer in the bodyin the body).
Aware that cancers rewire their metabolism in ways that could change the epigenome and that distant metastases in pancreatic cancer naturally spread to organs fed by a sugar - rich blood supply, the researchers wondered if the tumor cells had altered the way they use the basic form of sugar, glucose.
«We know that the pathway is important for normal cells to carry their activities as it is involved in regulating metabolism, that is, how cells process nutrients to obtain energy and how cells use energy to grow.
To address these questions, Dang, Altman, and Hsieh collaborated with Penn colleague, Aalim Weljie, PhD, research assistant professor of Pharmacology, using an osteosarcoma cancer cell line to study the interaction of MYC and metabolism in cancer cells.
Lead author Nora Volkow, a psychiatrist at the National Institute on Drug Abuse of the National Institutes of Health, recruited 47 healthy volunteers and used positron emission tomography (PET) scans to measure glucose metabolism in the brain while cell phones were placed over the right or left ear.
Researchers used data from different people's genotypes and metabolism to build personalized models that simulate how a drug will affect a particular set of cells in the body.
For example, when there is no oxygen (a likely scenario in underground disposal vaults) to help these bacteria «breath» and break down the ISA, these simple single - cell microorganisms are able to switch their metabolism to breath using other chemicals in the water, such as nitrate or iron.
Barzilai and colleagues laid out the case for using metformin in the June 14 Cell Metabolism.
From a theory dating back to the early 20th century by Nobel Prize laureate Otto Warburg, it has been believed that, in order to support their growth, cancer cells needed to increase their glucose consumption, without using mitochondrial metabolism.
This name can cause problems; in biology the word «respiration» can mean cellular respiration or metabolism (ATP generation inside cells), however sometimes (such as here) it can also refer to breathing (which is how the word is most often used by non-biologists).
The structure of this complex, determined using cryo - electron microscopy, shows how it converts near - infrared light into an electrical charge in order to power cell metabolism, which enables this bacterium to live at the extreme red limit of photosynthesis on Earth.
Further research showed that the WWOX gene plays a role in the altered metabolism of cancer cells which are known to use glucose differently to normal cells.
Sphingomyelinases like nSMase2 play a normal role in the cell's metabolism by breaking down fatty molecules into smaller components that cells use for every day functions.
Hydrogenases can also run in reverse, converting H2 into protons and electrons that can be used to power cell metabolism.
In the Nature Communications study, UTSW researchers also reported how miR - 17 causes cyst proliferation: the molecule essentially reprograms the metabolism of kidney cells so that cellular structures called mitochondria use less nutrients, freeing up resources to instead make cell parts that become cysts.
An international team led by metabolism experts Matthias Tschöp (Helmholtz Zentrum München / Technische Universität Müchen), Richard diMarchi (Indiana University) and Timo Müller (Helmholtz Zentrum München) report in the current issue of the journal Cell that liver - specific delivery of the thyroid hormone T3 using glucagon corrects obesity, glucose intolerance, fatty liver disease and atherosclerosis without causing adverse effects in other tissues.
Fat metabolism is the biochemical process by which fats are transported and broken down in the blood, and used by the cells of the body.
Now, using a powerful laser scanning microscope, George Brooks, an exercise metabolism expert at the University of California, Berkeley, and colleagues demonstrate that lactic acid is present in rat muscle cells regardless of oxygen content.
Proteins are the nano - machines that Nature uses to perform most of the processes critical for the metabolism in cells.
Human iPS cell - derived hepatocytes differentiated with our robust differentiation protocol and cultured using our novel maintenance medium provide an inexhaustible, consistent supply of functional hepatocytes that can be used to advance the understanding of diseases related to dysfunction in liver metabolism, including NAFLD / NASH, type 2 diabetes, and metabolic syndrome.
Human iPS cell - derived hepatocytes differentiated with our robust differentiation protocol and cultured using a novel maintenance medium provide an inexhaustible, consistent supply of functional hepatocytes that can be used to advance the understanding of diseases related to dysfunction in liver metabolism, including NAFLD / NASH, type 2 diabetes, and metabolic syndrome.
When cells become cancerous they use PKM2 in glycolysis instead, and Myc and HIF - 1a, the oncogenes that affect metabolism, may influence that switch.
Now available in the Early Edition of PNAS: Tom Williams (University of Bristol, UK) in collaboration with, among others, the Ettema - lab reports on using integrative modeling of gene and genome evolution to root the archaeal tree of life and to resolve the metabolism of the earliest archaeal cells.
Human satellite cell cultures display numerous features of mature skeletal muscles (1) and have been used for studies of muscle metabolism in cultures established from patients with type 2 diabetes and healthy control subjects (1 — 5,8,9,21,22).
Tom Williams (University of Bristol, UK) in collaboration with, among others, the Ettema - lab reports on using integrative modeling of gene and genome evolution to root the archaeal tree of life and to resolve the metabolism of the earliest archaeal cells.
T - Cell Enzyme Uses Deadly Multipronged Attack on Bacteria — GEN News Paper: Granzyme B Disrupts Central Metabolism and Protein Synthesis in Bacteria to Promote an Immune Cell Death Program — Farokh Dotiwala — Cell
Glutamine metabolism in rapidly proliferating cells instead makes use of a linear version of the TCA cycle, aptly named glutaminolysis [102].
We are interested in the mechanisms of tRNA aminoacylation in mitochondria, and how this reaction is used to coordinate the cycle of mitochondria with the rest of the cell's metabolism.
Before the genetic information stored in DNA can be used to direct cell growth and metabolism, it has to be transferred into RNA.
Using an RNA interference screen, Swanton and his colleagues identified a set of genes involved in the regulation of mitotic arrest and in the metabolism of ceramides, lipid molecules abundant in cell membranes that influence whether tumors are sensitive to certain chemotherapy agents.
In 2013, Peterson and his colleagues Joanna Yeh and Keith Joung were first to use the new technology to engineer a new strain of animal — a zebra - fish missing the GSK3ß gene, which encodes an enzyme involved in energy metabolism and the development of cell and body structures as an embryo growIn 2013, Peterson and his colleagues Joanna Yeh and Keith Joung were first to use the new technology to engineer a new strain of animal — a zebra - fish missing the GSK3ß gene, which encodes an enzyme involved in energy metabolism and the development of cell and body structures as an embryo growin energy metabolism and the development of cell and body structures as an embryo grows.
In his research, Schroeder uses C. elegans, an important model system for human disease, to investigate how novel cell metabolism products function as signals between individuals and within cells.
The human metabolism is a complex system, but here's what you need to know to understand how our bodies use food to produce energy: When we eat (especially carbohydrate - loaded foods) our insulin levels rise, which stimulates our cells to take in glucose.
Every cell of your body uses thyroid hormones; they balance your metabolism, take in iodine and regulate your metabolism while interacting with all your hormones
So cancer's primarily — primary fuel if you look at Otto — Otto Warburg or Otto Van Warburg, a German scientist in the 30s and 40s who got 2 Nobel prizes discovering this physiology around cancer cell metabolism and he found that cancer cells primarily survive on glucose and if you can starve the cancer cells of that metabolic fuel — remember it burns dirty — if we can use ketones, we can essentially starve that type of cell.
The thyroid plays an essential role in the human body which includes cell reproduction, general nerves functioning, metabolism, growth and how cellular oxygen use.
It is essential for the metabolism of carbohydrates and fats and assists insulin in transporting these nutrients into cells in order for it to be used as energy.
Don't take pills, eat more veg... 15.04.2014 Animal study: cranberries are an anti-aging drug 19.03.2014 Polyphenols in food extend life expectancy 08.02.2014 Six things you can do to if you want to live to a hundred 13.01.2014 More magnesium, longer life expectancy 27.12.2013 Magnesium - rich diet reduces mortality risk 10.11.2013 Tour de France cyclists live six years longer 19.10.2013 EGCG protects liver and kidneys, and extends life expectancy 04.08.2013 Sedentary lifestyle causes body to deteriorate faster 30.06.2013 More exercise improves quality of life on all fronts 28.06.2013 Positive emotions extend life expectancy by ten years 13.06.2013 Your word use reveals the age you are likely to reach 11.05.2013 Positive view of life after retirement extends life expectancy 29.04.2013 No fear in the face of aging extends life expectancy 23.04.2013 Sleep less and you're more likely to die 03.04.2013 Better health = more sex 15.02.2013 Glaucarubinone extends life expectancy and boosts metabolism 19.01.2013 Animal study: L - theanine extends life expectancy 21.12.2012 Child that still needs you lengthens your life expectancy 05.12.2012 Alpha - carotene: the life elixir in carrots 30.10.2012 Live longer with Horny Goat Weed 27.10.2012 The more muscle you have the longer you live 01.10.2012 Caffeine and paracetamol are longevity drugs 28.09.2012 Animal study: epicatechin from cacao extends life expectancy 18.07.2012 Join Greenpeace and double your chance of good health 15.07.2012 Coffee reduces mortality risk — but effect is minimal 01.07.2012 Dean Ornish diet makes your cells younger 17.06.2012 Vitamin S prolongs your life 16.06.2012 Combined effect of not smoking, healthy eating and exercise is tremendous 13.06.2012
Metabolism has two distinct divisions: catabolism, in which the cell breaks down complex molecules to produce energy and reducing power, and anabolism, in which the cell uses energy and reducing power to construct complex molecules and perform other biological functions.
Whether that glucose comes from carbohydrates, from protein via gluconeogenesis, or from glycerol (a byproduct of fatty acid metabolism), excess amounts in the blood stream that aren't immediately used are transported by insulin to muscle and liver cells and get converted to glycogen.
Copper is required for hemoglobin production in red blood cells, production and function of white blood cells, the absorption, transport and use of iron, energy metabolism, the development, growth and maintenance of bone and connective tissue, the formation and maintenance of myelin sheath (outer surface of nerve fibers), adrenal hormone production, thyroid hormone production, muscle tone, immunity, reproduction, tissue repair, pigmentation of hair and skin, and proper growth and development of infants and children.
The endocrine system is responsible for releasing hormones which control growth, sexual development, and how your body uses and stores energy or metabolism; every cell in our body depends on thyroid hormones for regulation and metabolism.
Bruce Blumberg, professor of developmental and cell biology and pharmaceutical sciences at the University of California, Irvine, who coined the term «obesogen,» studies the effect that organotins — a class of persistent organic pollutants that are widely used in the manufacture of polyvinylchloride plastics, as fungicides and pesticides on crops, as slimicides in industrial water systems, as wood preservatives, and as marine antifouling agents — have on the body's metabolism.
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