Not exact matches
Since randomized
clinical trials — the gold - standard
in research — don't accommodate patients» preferences, Zoellner and her research team
used a study design called a «doubly randomized preference
trial» to investigate whether giving patients a choice affects their treatment outcomes.
Since HDAC inhibitors are currently
in clinical use for cancer and are
in trials for treatment of metabolic and neurological diseases, these new findings call for a re-thinking about how they work, say the authors.
The diabetes drug rosiglitazone has been under intense scrutiny
since a 2007 study
in the New England Journal of Medicine looked at more than 40
clinical trials and linked the drug's
use with increased risk of heart attack and death from heart disease.
There are very limited studies on pregnant women determining the effects of hydroquinone on pregnancy (
since I assume most pregnant women don't want to be part of such
clinical trials...), but due to hydroquinone's high absorption rate and animal studies reporting carcinogenic effects
in rats, it's recommended pregnant and nursing women avoid
using this chemical.