Sentences with phrase «used systems biology»
M.Y.: That is exactly why: How could we use systems biology to address the rational use of therapeutic drugs?
http://www.sciencemag.org/
Borenstein and his team use a systems biology approach and apply sophisticated computer modeling to understand the structure, function, and dynamics of the microbiome.
By using a systems biology approach, researchers deliberately move away from the classic reductionist manner of looking at molecules in isolation to study biological systems in their entirety.
Extending cytokine / chemokine profiling platform (UNISI): Improvement of currently available services will be particularly focused on the optimisation of cytokine profiling for vaccine relevance using a systems biology approach.
From correlation to causation: analysis of metabolomics data using systems biology approaches — Antonio Rosato, Metabolomics
Characterization of infectious disease pathogenesis and host - pathogen interactions using systems biology methods
This program is highly interconnected with programs 1 and 2, since we aim at exploring TSLP biology in various inflammatory using systems biology approaches.contexts
Our global aim is to reconstruct such networks by focusing on individual components (cells, soluble factors, membrane receptors), or by integrating multiple components using systems biology and modeling.
One approach uses systems biology strategies to better understand tumor progression and resistance to cancer therapeutics as well as to identify clinically useful biomarkers.
Her ongoing clinical training through the Institute for Functional Medicine uses a systems biology approach when working with those who suffer from chronic and acute conditions to help them find their path to healing.
Functional medicine uses a systems biology approach, which is a study of how our body's biological systems interact functionally with environment over time.
Not exact matches
Without going into a complicated biology lesson (which I probably would not be prepared to teach), let's simply think of what our digestive system does for us: it breaks food down into smaller pieces so that our body can use this nourishment to build new cells and give us energy.
He added that the method used in this study, called «network biology» — where computer systems are used to identify gene networks that work together to underpin disease — may also help find treatments for other conditions.
The fields within biology are further divided based on the scale at which organisms are studied and the methods used to study them: biochemistry examines the fundamental chemistry of life; molecular biology studies the complex interactions of systems of biological molecules; cellular biology examines the basic building block of all life, the cell; physiology examines the physical and chemical functions of the tissues and organ systems of an organism; and ecology examines how various organisms interrelate.
The collaborative effort may be the best means of putting to practical use the emerging (and still esoteric) field of systems biology, which studies complex interactions in biological systems.
Lead author Yarden Katz, a fellow at the center and in the department of systems biology at Harvard Medical School in Boston, says they were interested in examining the relationship between NIH funding and metrics widely used to indicate scientific quality and determine career advancement, such as publication, citation, and patent counts.
WeizMass and MatchWeiz are not limited to the study of plant metabolites but may also be used to investigate the biology of other living systems, including animal and human metabolism.
Using a combination of systems biology and bioinformatic techniques, the scientists cleverly isolated proteins, which, when mutated, abolished the plant's ability to respond to CO2 stress.
A biologist, Schaal was among the first plant scientists to use molecular biology - based approaches to understand evolutionary processes in plants and she has worked to advance understanding of plants» molecular systems and population genetics.
His laboratory uses a multidisciplinary approach encompassing systems biology, molecular pharmacology, biochemistry / proteomics, cell and structural biology, and computation / bioinformatics.
The researchers developed algorithms to use in a «systems biology modeling cycle,» in which they repeatedly fit a model to gene expression data obtained from laboratory experiments until a good fit was obtained between the predicted and the measured outcomes.
Through iGEM, interdisciplinary teams of supervised students or community lab members throughout the world engineer genetic systems, using standardized biological parts, to tackle a broad variety of global synthetic biology challenges, from producing sustainable chemicals to detecting environmental contaminants.
There are ongoing studies which focus on the discovery of molecular biomarkers of the VSV - ZEBOV vaccine in healthy individuals using omics - based technologies in combination with a systems biology approach,» says Ali Harandi.
People who are trained in systems biology are just used to the idea of collaboration to get the job done — to answer the questions.»
«As far as we know, this is the first time anyone has used an insect system as a model for NIHL (noise - induced hearing loss),» says Daniel Eberl, UI biology professor and corresponding author on the study.
Jeff Smith, a first - year postdoc at OISB who studies cell signaling using proteomics, notes that with no specific categories for systems biology on research - grant applications, he has no choice but to place himself in direct competition with biochemists and biologists in other fields.
Working on Arabidopsis, a model plant used widely in plant biology labs, Cutler and his colleagues focused their efforts on tinkering with one of the plant endogenous systems involved in drought responses.
«Mantis shrimp, or stomatopods, are well known for aggressive temperaments and complex visual systems, but until now we've known very little about whether and how they use color to communicate with other mantis shrimp,» said Amanda Franklin, a Ph.D. student in the biology department of Tufts University's Graduate School of Arts and Sciences and the first and corresponding author on the paper.
If life today is the result of evolution by natural selection, Darwin realized, then even the most complex systems in biology must have emerged gradually from simple precursors, like someone crossing a river using stepping - stones.
«Biological timing: Biologists investigate the mechanism of an auxiliary clock: Researchers use new systems biology methods on plants.»
«Now that we have the cellular and molecular information, the future promises to be very exciting when this knowledge can be used to understand how this system is formed during gestation and how the different neuron types go about controlling the body's functions,» says study leader Patrik Ernfors, professor of tissue biology
«A second innovation is the use of synthetic biology concepts, the modularization of the parts, and integration with a robotic system, so we can do it in high - throughput.»
The research group, led by Erika Matunis, Ph.D., a professor of cell biology at the Johns Hopkins University School of Medicine, has been using the fruit fly as a model living system in which to study stem cells in their natural state.
We use a combination of genomics, systems biology, biochemistry, bioinformatics and molecular biology to investigate the networks formed by RNA binding proteins, miRNAs and their target genes and evaluate their impact on biological processes, cancer and disease states.
The Transcriptomics Core Facility supports a systems biology approach in vaccine development focusing on the identification of transcriptomic correlates of vaccine immunogenicity and efficacy for a range of novel and licensed vaccines using PBMC or whole - blood and BAL fluid samples.
Couple that with a condition known to the plant community as «plant blindness» - the tendency for students to be more interested in studying animals than plants, and biology teachers» preference for using animal systems to demonstrate biological concepts - and you have yourself a plant publicity crisis.
The team, which also includes Raul Rabadan, PhD, professor of systems biology and biomedical informatics at CUMC, will use single - cell genomics to create a unique, genetic ID tag for each cell in the spinal cord.
It uses cutting edge approaches to understand entire systems involved in complex biology, from a cell to the central nervous system.
Our Human Emulation System sets a new standard for recreating true - to - life human biology and is being used to advance product innovation, design, and safety across a range of applications including drug development, agriculture, cosmetics, chemical - based consumer products, and personalized health.
Development of a gene expression assay in non-human primates: We will develop a novel sensitive assay for the characterisation of vaccination - related gene expression profiles in NHPs, using an approach that is fully harmonised with the systems biology platform.
Samples will also be available for use in the systems biology platform.
Using the cichlid fish species as a model system gives us valuable insight into human biology and disease.
We use a combination of systems biology, protein functional characterization, and biophysics to explore polysaccharide biosynthesis at multiple scales.
We study the cell biology, binding proteins, structure and regulation of these important enzymes, using neuroendocrine cell lines as model systems.
Using synthetic biology approaches, I am engineering fluorescent organisms to monitor mechanical sensing systems in response to pressure.
The research, published in the Proceedings of the National Academy of Sciences in September 2017, uses a combination of real - world bacterial culture results and medical records from nursing home patients, and a computing approach known as systems biology.
«It validates the approach of using even very distant model systems, such as the fly, to study human biology.
Krogan described the CCMI as a «cross-UC program focused on using quantitative systems tools to help understand the underlying biology behind the genomic data derived from breast, head and neck, and other cancers.»
Maria Harrison will participate in a $ 13.5 million, multi-institution systems biology project with Daniel Schachtman of the University of Nebraska - Lincoln to develop sorghum that is more drought resistant and uses nitrogen more efficiently.
2016 — Gloria Coruzzi - a leader in exploring the interface of plant and systems biology and provided the first integrated view of mechanisms controlling the assimilation and use of nitrogen.