Sentences with phrase «used vaccine viruses»

Not exact matches

«The holy grail is to target a piece of the virus by antibody or t cell,» Tom Evans, the CEO of a company called Vaccitech that is working on a universal vaccine they hope can be used to treat all strains of influenza A, told National Geographic.

5Zika vaccine: Florida Gov. Rick Scott, who has been highly critical of the federal response to the outbreak of the Zika virus, used his emergency powers Thursday to direct $ 25 million in state money toward helping to develop a vaccine.

The manufacturer of the sole dengue vaccine on the market says a new study shows that it should only be used in people who have had a previous infection from the mosquito - borne virus.

Together with researchers at the CNRS, the group has demonstrated the efficacy of RNA - based vaccines produced using the new method against plant virus infections.

In the new study, researchers at the NIAID used a virus - like particle vaccine cocktail that expressed a handful of different subtypes of a key surface protein of the influenza virus: hemagglutinin H1, H3, H5 and H7.

It's with the inactivated virus, the dead - vaccine virus that Dr. [Jonas] Salk made in the 1950s (versus the live vaccine coverage that [Albert] Sabin developed, which we mainly use in the vaccination program).

The reason the oral vaccination is used in the vaccine campaign is it provides intestinal immunity that is so crucial in stopping the person - to - person transmission spread in settings where you might have a high transmission rate of the virus — like in tropical areas or areas with suboptimal sanitation.

They hypothesized that using lower dosages and intradermal, rather than intramuscular, injections would extend the virus vaccine supply.

Based on our knowledge of the flu virus and the human immune system, we can use computers to design the components of a vaccine that gives much broader and longer - lasting protection.»

Researchers have made headway in understanding the H5N1 virus; they have created new vaccines and are looking into other possible treatments, such as using antibodies from survivors.

Vaccines developed using proteins rather than live viruses can help protect animals and subsequently humans from insect - borne viruses, according to Alan Young, chief scientific officer for Medgene Labs, an animal health company that develops therapeutics and diagnostics, including vVaccines developed using proteins rather than live viruses can help protect animals and subsequently humans from insect - borne viruses, according to Alan Young, chief scientific officer for Medgene Labs, an animal health company that develops therapeutics and diagnostics, including vaccinesvaccines.

The so - called STEP trial, sponsored by pharmaceutical giant Merck & Co. and the federally funded HIV Vaccine Trials Network (HVTN), was the first to test the idea of stimulating the immune system's killer T cells to hunt for the virus more aggressively, in this case using a weakened form of the cold virus to carry three genes from HIV.

At the centre of the theory is the plausible, if unlikely, speculation that a direct forerunner of HIV contaminated monkey cells that were used to grow polio virus for the vaccines.

Unlike any other vaccine designed for human use, this product would be a DNA vaccine that only contains a particular part of the pathogen (rather than a vaccine with an inactivated live or dead virus, for example).

There is currently no Zika vaccine, so preventing mosquito bites and using condoms — the virus can also be spread by human sexual contact — remain the predominant ways to combat its spread.

Novavax says that during Phase IIa of seasonal flu vaccine testing, which began in May, it was able in the majority of people tested to surpass the FDA's requirements for producing enough antibodies to protect the body from the H3N2, H1N1 and B viruses — all of which were common enough a year ago to be used to develop flu vaccines for the 2008 to 2009 flu season.

«In addition, this platform can be used to develop safe vaccine candidates for other flaviviruses such as Zika virus, where pregnant women are the target group for vaccination.»

Flu vaccines are designed to prevent infection by eliciting antibodies against HA, which the virus uses to break into cells lining the airways.

To create a new dengue virus vaccine, Stefan Metz, Shaomin Tian in the laboratories of Aravinda de Silva, Chris Luft and Joe DeSimone at the University of Carolina, Chapel Hill, USA designed nanoparticles of various shapes and sizes using Particle Replication in Non-wetting Template (PRINT) technology.

One reason vaccines using weakened flu virus are not used in the elderly is that they have been exposed to many strains of flu virus over the years and have more antibodies in the nasal tract, which can inhibit the weakened flu virus from infecting and stimulating the immune response necessary to protect against the virus.

After several days of incubation the eggs are opened and the virus is removed, purified and used to make the vaccine, as a 2004 Scientific American article points out.

Attempts at using live dengue viruses to develop a dengue fever vaccine have often led to an imbalance in immunity to the four dengue serotypes — for instance, one recent candidate had lower efficacy against serotype 2.

For their research, Pekosz and his team, using human nasal tract cells, studied the weakened strain of the flu virus that is used in the nasal spray vaccine and compared its behavior with that of the flu virus itself.

In addition, vaccine - makers that use eggs can not begin developing new vaccines that target new virus strains until the U.S. Centers for Disease Control and Prevention (CDC) creates a live - virus reference strain for these companies to work with, a process that could take several weeks.

The company's vaccine approach in both cases is to use viruslike particles (VLPs) containing surface proteins that make the VLPs resemble a virus, thereby eliciting the proper immune response — even though the VLPs lack the genes needed to replicate themselves.

In 2016, cryo - EM was used to map the structure of the Zika virus (SN: 4/30/16, p. 10), helping to identify possible regions to target with a vaccine or antiviral compounds.

In any given season, the effectiveness of the vaccine depends on how good a match there is between the viruses used in the drug's production and the strains that are actually circulating that year.

In 1967 and 1968, Yugoslavia conducted a mass polio vaccination campaign using polio virus propagated in WI - 38 cells; Sweden and Switzerland had already run trials of the same vaccine.

As the number of cases of the paralytic disease fall, world health officials have to grapple with a vexing problem: a component of the most widely used polio vaccine now causes more disease than the virus it is supposed to fight

And Indian vaccine companies, which can produce vaccine more cheaply, hope to make their own IPV not from wild polio, which is risky to handle, but from the weakened virus used in OPV.

Protein chemist Michael Way, cell biologist Sally Cudmore, and their colleagues at the European Molecular Biology Laboratory in Heidelberg and at the Pasteur Institute in Paris have found that vaccinia — a virus used in smallpox vaccines — surfs through cells on piles of actin, one of the basic structural proteins in the cellular skeleton.

Notably, because no live viruses are used in their manufacture, VLP vaccines do not need to be produced under high - level biocontainment conditions.

Vaccines block virus entry by making good use of such responses.

«Vaccines are somewhat effective but can have limited use when viruses like influenza rapidly mutate from year to year.

The live - attenuated vaccine, VSV - EBOV, uses genetically engineered vesicular stomatitis virus (VSV) to carry an EBOV gene that has safely induced protective immunity in macaques.

Some newer vaccine candidates use harmless viruses such as modified adenoviruses to deliver genes that encode immunizing viral proteins.

The new candidate vaccine is the first to show such potent and long - lasting protection without the use of a live virus.

These vaccines, however, are not effective against viruses — so one solution is selecting parent fish with virus - resistant traits to use as broodstock for salmon egg production.

This study used vaccines prepared from killed viruses that are the basis of flu shots.

«Now that we know the mice can be vulnerable to Zika infection, we can use the animals to test vaccines and therapeutics — and some of those studies are already underway — as well as to understand the pathogenesis of the virus,» said senior author Michael Diamond, MD, PhD, a professor of medicine at Washington University.

Although the world's attention is focused on the novel H1N1 virus causing the swine flu pandemic, H3N2, a seasonal strain of influenza, has popped up in many East Asian countries — and some variants in circulation may outfox the seasonal vaccine in use.

The chimpanzee virus could be used to make vaccines to various pathogens, including hepatitis, human papillomavirus, and HIV.

Bachmann has had similar success with an asthma vaccine that uses the same virus - bacteria combination.

This vaccine uses an inactive herpes virus (stripped of its viral genes) to transport a small amount of Aß as well as another protein called interleukin - 4 that may help prevent brain inflammation.

The protein could be used to develop vaccines or treatments to protect people from the MERS virus, an international team of researchers...

He wonders whether it's not vaccinia, the virus used to induce smallpox resistance, but some other component of the vaccine that's prompting inflammation, perhaps bovine cells from the manufacturing process.

The company uses cells to grow the virus for the vaccine and claims that this «shows significant time saving» over traditional production with eggs.

Some 40 years ago, the virus SV40 was discovered in the monkey kidney extracts used to make the Salk vaccine.

The protein could be used to develop vaccines or treatments to protect people from the MERS virus, an international team of researchers reports July 27 in the Proceedings of the National Academy of Sciences.

Sun is currently conducting collaborative research with hydrogels for applications and efficiency with anticancer drugs screening and delivery, stem cells and wound healing, as well as being used in vaccines for H1N1 influenza and animal diseases, such as the porcine reproductive and respiratory syndrome virus, or PRRS.