Sentences with phrase «useful biomarkers of»

The measurement of ITC, indoles and conjugated metabolites are useful biomarkers of dietary exposure to cruciferous foods.

In addition to suggesting that creatine could slow the progression of HD, these results also imply that neuroimaging may provide a useful biomarker of disease modification in studies of other potential treatments.

Not exact matches

Instead, he plans to narrow the list of useful biomarkers, then develop antibody - based tests for clinical use.

Even if high levels of these amino acids are not causing diabetes, evidence suggests they are useful biomarkers for predicting who is at risk, enabling such people to adjust their lifestyle before they get sick.

«This study highlights the importance of confirming the validity of potential biomarkers in a relevant, large animal model and will be useful in the design of future clinical trails,» commented lead investigator Stephen J. Kolb, MD, PhD, Associate Professor, Department of Neurology and Biological Chemistry & Pharmacology, The Ohio State University Wexner Medical Center, Columbus, OH.

«This may serve as a clinically useful biomarker to identify a subset of difficult - to - treat asthmatic children, and targeting the VNN - 1 pathway may be useful as a therapeutic strategy.»

«This confirms that while unique to each individual, some aspects of the family connectome are inherited and maintained throughout development and may be useful as early biomarkers of mental or neurological conditions,» said lead author Oscar Miranda - Dominguez, Ph.D., research assistant professor of behavioral neuroscience, OHSU School of Medicine.

Meanwhile, researchers from the University of Rome found that texture analysis provides useful «imaging biomarkers» that indicate how the tumor is responding to chemotherapy and radiotherapy.

By providing a means to link proteins directly to specific cell types, the authors believe that this new method will be useful in studies of cell - cell communication and biomarker discovery.

Abnormal levels of the proteins may be useful biomarkers that could help us study early treatments to limit or reverse the damage to brain cells and even prevent the development of the full - blown disease,» said study author Edward Goetzl, MD, a Professor of Medicine with the University of California, San Francisco, a researcher at the National Institute on Aging, and a scientist of NanoSomiX, Inc., a California - based biotechnology company that provided a grant for method development for the study.

This level of granularity in biomarker classification, combined with genetic and clinical information, will presumably be useful in tailoring treatment to the individual when appropriate specific treatments become available.

Dr. Qimin Zhan, Principal Investigator of this project and the Director of State Key Laboratory of Molecular Oncology, Chinese Academy of Medical Sciences Cancer Hospital, said, «For sure, the findings of this project provide novel insights into understanding of underlying mechanism for this malignant ESCC, and enable us to explore potential diagnostic biomarkers and drug targets, and to develop useful clinical therapeutic approaches.

Attempts to use a small number of biomarkers, whether analytes in blood, cerebrospinal fluid, or a handful of genetic loci, have not yielded diagnostically useful tests for CFS.

The third is the development of metabolite measurements as useful biomarkers / alternative end points.

Given that these protein biomarkers have not, in general, proved useful for early detection, if their contribution to the performance of this test is substantial, it would question the likely utility of the test in clinical practice.

Small - world metrics can characterize the functional organization of the brain in AD, and our findings further suggest that these network measures may be useful as an imaging - based biomarker to distinguish AD from healthy aging.

In the last decade we have witnessed tremendous advances in our understanding of the landscape of the molecular alterations that underpin many of the most prevalent cancers, in the use of automated high - throughput platforms for high - throughput drug screens in cancer cells, in the creation of more clinically relevant cancer cell models, and lastly in the development of more useful computational approaches in the pursuit of biomarkers of drug response.

«That's why we examined specific biomarkers in the mother's blood in the second and third trimester of her pregnancy to determine if they are useful in identifying children who could benefit from early interventions,» Chambers said.

An ELISA method for measuring 2 - and 16 - alpha - hydroxylated estrogen (OHE) metabolites in urine is available and the ratio of urinary 2 - OHE / 16 - alpha - OHE (2 / 16 - alpha ratio) is a useful biomarker for estrogen - related cancer risk.

Thus, salivary cortisol can be a useful biomarker in many settings, if caution is taken in the choice of methods used.