Sentences with phrase «useful drug target»
This is a welcome surprise, because it suggests a well - understood brain process might be a useful drug target for future HD research.
https://en.hdbuzz.net/
The distinction is crucial for understanding how atherosclerosis develops as well as determining whether CRP is a useful drug target — and whether lowering it can save lives.
Not exact matches
The drug that they have developed appears to target cancer stem cell activity, which suggests it will prevent metastatic recurrence and be useful in combatting drug resistance.»
These bubbles are thousands of times smaller than the tip of a pencil lead — so small they are invisible even under most optical microscopes — and their stability makes them useful in a variety of applications, from targeted drug delivery to water treatment procedures.
In some cases, the off - target effects of a drug could make it useful for treating conditions other than the one for which it was originally developed.
New drugs targeting these pathways may be useful against a variety of different cancers.
Target - based screening has enabled scientists to discover many useful new drugs, but some wonder whether this basic discovery strategy has already taken all the «low hanging fruit.»
The ability to design new protein nanostructures could have useful implications in targeted delivery of drugs, in vaccine development and in plasmonics — manipulating electromagnetic signals to guide light diffraction for information technologies, energy production or other uses.
These include Cenix Bioscience, which has developed a new lab technique to identify the genes that are involved in cell division, predicted to be very useful for finding potential new targets for anticancer drugs.
«The induced pluripotent stem cells we used in this study proved to be extremely useful in disease modelling, and they could offer an excellent platform for drug discovery and testing new therapeutic targets for Alzheimer's disease in the future,» says Early Stage Researcher Minna Oksanen, the lead author of the study.
«In drug development, the focus is typically on increasing the strength of interaction with a drug target, but here we found that weakening an interaction was useful.
The replicon, however, could become «enormously useful» as a target for testing potential drugs against HCV, says Stanley Lemon of the University of Texas Medical Branch at Galveston.
The role of academic scientists in this process has largely been to explain the genetic / cellular basis of diseases for identifying useful targets and provide new chemical and computational methods to improve the pharmacological profile of potential drugs.
Previous work at CU Cancer Center shows these drugs are especially useful against lung cancers that over-express both EGFR and HER2, implying that in addition to targeting HER2 - positive lung cancers with drugs approved to treat HER2 - positive breast cancers, there may be a role for HER2 inhibitors in HER2 cancers, perhaps both breast and lung.
Dr. Qimin Zhan, Principal Investigator of this project and the Director of State Key Laboratory of Molecular Oncology, Chinese Academy of Medical Sciences Cancer Hospital, said, «For sure, the findings of this project provide novel insights into understanding of underlying mechanism for this malignant ESCC, and enable us to explore potential diagnostic biomarkers and drug targets, and to develop useful clinical therapeutic approaches.
Almo's group, for instance, is now investigating proteins involved in the immune system, to look for molecules that could be useful as drugs or drug targets.
Over the next 18 months, deCODE and Pfizer will work together to analyse the genomes of patients to search for sequence variants that would be useful for understanding drug targets and discovering novel drug targets, that may ultimately lead to tools for patient stratification and companion diagnostics.
While scientists previously thought that a drug targeting TGF - ß would only be useful in advanced cancers, she discovered that the same drug may help prevent precancerous cells from turning into cancer.
The discovery, published online in the Journal of Natural Products, shows that a compound isolated from this common plant with low branches and creamy, white fragrant flowers appears to be useful for the development of drugs targeting the parasite Plasmodium falciparum.
One postdoc in Peterson's lab, for example, is using zebrafish to study opioid addiction, trying to identify genes that heighten drug - seeking behavior and thus could be useful targets for helping human addicts.
However, other types of imaging could be useful for HD research, like one that measures PDE10, the target for Pfizer's HD drug.
Both angiotensin II receptors are important drug targets, since the blockade of AT1R has anti-hypertensive effects, while the modulation of AT2R could be useful for cardioprotection, neuropathic pain relief and the treatment of several other conditions.
«It's Orwellian that the biggest target of the DEA's Eradication Program is actually not a drug but instead a plant useful for everything from food to clothing to even auto parts, which currently must be imported to supply a $ 270 million industry,» says Eric Steenstra, President of Vote Hemp.
Additionally, it seems to be particularly beneficial for teens of parents who were using drugs at baseline, information useful in targeting adolescents who can best benefit from this intervention.