It's also what makes
them useful models for human disease,» she said.
But Franklin and others suspect that in their zeal to clean up, facilities may have wiped out some of the microbial complexity that makes mice
useful models for human disease.
Not exact matches
«Finches offer researchers a new tool with which to study Huntington's
disease: Like
humans, songbirds learn their vocalizations, suggesting they could be
useful as
models for certain disorders.»
The researchers hope their new cell lines will be a
useful resource
for studying the cellular and molecular intricacies of Huntington's further, and suggest they may provide a
model for examining other
diseases of the brain that are specific to
humans.
She added that, «attempts to generate the cerebellum from
human iPS cells have already met with some success, and these patient - derived cerebellar neurons and tissues will be
useful for modeling cerebellar
diseases such as spinocerebellar ataxia.»
However, Takebe's liver bud has the advantage of being grown from iPS cells, rather than,
for example, the primary
human hepatocytes used in Bhatia's graft, which could make it
useful in
modelling rare
diseases or examining the specific genetic backgrounds of the iPS cell donors.
«This is an interesting paper presenting a potentially
useful preventative therapy
for Alzheimer's
disease but, while mouse
models are very
useful, we have to be very careful about the interpretation of the data in relation to the
human condition.
Animals provide a
useful model for diseases found in both
humans and other animals.
Mouse
models are
useful for studying Alzheimer's
disease, but they have their limitations when comparing results in
humans.
Development of a comprehensive system which can enrich hPSC - CMs will be ultimately
useful for cell therapy
for diseased hearts,
human cardiac
disease modeling, cardiac toxicity screening, and cardiac tissue engineering.
Taken together, these results demonstrated that
disease - specific
human iPS cell — derived hepatocytes are capable of
modeling key pathological feature of A1ATD in vitro and may also prove
useful for future drug screening assays.