In harmony to the present suggestion, the scoring and image cytometry evaluation using immunohistochemistry of Cyclin D1 protein
marker stated that the variations of protein expression in tissue sections could yield
prognostic information or could be
useful in determining subtle effects of curative or prevention therapies [31].
Although there is currently no technology that allows early diagnosis of the disease, a number of putative
markers have been identified: their detection after diagnosis would be a
useful tool to monitor the evolution of the tumor during treatment, providing valuable
prognostic information on response to a given therapy.