By identifying novel biological pathways and publishing details of these interactions, the study team aims to help uncover
useful targets in developing better vaccines and cancer treatments.
Activating transcription factor 4 (ATF4): Increased levels of ATF4 in the liver are found in many of the methods of slowing aging in laboratory species, though it is unclear whether or not that makes this protein
a useful target in and of itself.
Not exact matches
«While you might think some of this stuff is extraneous, a good number of these things might actually be
useful later if you want to
target them outside of the office or
in their homes, etc..
Primarily
targeted to the military and outdoors people, the products can also be
useful in refugee camps, where water for things like bathing is
in short supply.
The duo focuses on providing
useful and
targeted information
in their posts whether it's through their website, weblog, or twitter account.
Craft very meaningful and
targeted questions to ensure that the results will be
useful in future implementation of this feedback.
This is why the deal makes so much sense: AOL provides the technology to
target individuals instead of content, and Verizon the ability to track those individuals — at least the over 100 million customers they already have — at arguably a deeper level than anyone else
in digital advertising (for non-Verizon customers, AOL's ad platform is still
useful, albeit not as
targeted; rates would be commensurately lower).
Perhaps it would be
useful to do some experiments or demonstration projects
in distressed areas to see what policy designs work best for these
targeted job creation policies.
And
in the process, it's collecting
useful data for
targeting them more closely.
To illustrate the practical application of the inflation -
targeting framework
in Australia and its flexibility, it is
useful to focus on the operation of monetary policy
in three particular episodes (Graph 2).
Kogan said that the data he collected likely couldn't have been very
useful in a
targeting political campaign, a claim which has been supported by media reports.
Even before Google rolled out their first Google Panda update
in February 2011, the best search marketers knew that quality, valuable, and
useful content should
target a particular group of people.
It would be
useful if you could post your
target weightings
in the table every time you post the table so we get an idea of how far you drift from your
targets before rebalancing.
If, before the stimulus, government finances were
in good shape, as was the case
in China, then stimulus does indeed stimulate: The modest budget deficit that it causes is easily financed, and the extra spending creates some jobs and maybe some
useful infrastructure, depending on how well
targeted it is.
I find that we can get really
useful persona information by interviewing 4 - 5 people
in the
target audience.
Fill your business page with as much
useful information as possible, utilizing
targeted keywords
in the «About» section.
Analysts say the country is reluctant to
target militants it has historical ties with and who could be
useful allies
in Afghanistan once foreign troops withdraw.
Which change - growth methods are
useful in each sphere of this
target?
Interventions
in urban - fringe and rural stores
targeting the shelf space of healthy foods and the placement of soft drinks at key displays may be
useful obesity prevention initiatives.
It is games like this
in which the talents of Giroud can be most
useful, as we can use the width of the pitch and get balls
in the box to exploit his size and power
in the air, while his strength and ability as a
target man to hold the ball up and bring other players around him into the game is a huge weapon.
But this was a game a player like Giroud would've been
useful because we had a lot of the ball on the wings and no
target man
in the box.
It remains to be seen if United will push harder for Luiz or explore alternative
targets in that position, though any centre - back signing would be
useful for Mourinho at this stage due to the recent injury sustained by Eric Bailly.
Consequently, it may be a
useful target to use for interventions
in mothers with depression that improves outcomes for infants and their mothers.
Likewise, if you apply too many demographic criteria (upper - income women
in Texas Congressional District 5 who are aged 30 - 45, with children, are registered Republicans but who haven't voted
in the past two elections), you can end up with
target universes that are too small to be
useful, a great example of diminishing marginal returns.
Data experts I've talked with generally say that psychographic models can be
useful in your first rounds of outreach, since they should give you at least an idea of whom to
target.
«The introduction of calisthenics to schools» scheme is not by chance, but an integral part of the total transformation of education
in the state
targeted at the eventual production of
useful future citizens.
Taking their lead from some of the best US campaigns, parties have been making extensive use of polling, local intelligence from voters, and additional
useful information like consumer data, to produce microtargeted campaigns to raise turnout amongst specific groups
in target seats.
In Pakistan, in contrast, bombings are driven by religious differences between people who are ethnically much more similar within a multi-ethnic panorama of predominantly Muslim ethnicities - indeed, often the targets of bombings are secular people, or Christians, or less «fundamentalist» Muslims of the same ethnicity as the bombers, so simple ethnic profiling is not very useful in making a first order assessment of the risk that someone is a bomber and generates vastly more false positive
In Pakistan,
in contrast, bombings are driven by religious differences between people who are ethnically much more similar within a multi-ethnic panorama of predominantly Muslim ethnicities - indeed, often the targets of bombings are secular people, or Christians, or less «fundamentalist» Muslims of the same ethnicity as the bombers, so simple ethnic profiling is not very useful in making a first order assessment of the risk that someone is a bomber and generates vastly more false positive
in contrast, bombings are driven by religious differences between people who are ethnically much more similar within a multi-ethnic panorama of predominantly Muslim ethnicities - indeed, often the
targets of bombings are secular people, or Christians, or less «fundamentalist» Muslims of the same ethnicity as the bombers, so simple ethnic profiling is not very
useful in making a first order assessment of the risk that someone is a bomber and generates vastly more false positive
in making a first order assessment of the risk that someone is a bomber and generates vastly more false positives.
This commitment could
in some ways secure Cameron's right - wing flank and benefit UKIP by allowing them to focus resources on more
useful targets.
The robots could be
useful in cancer treatments, because they can
target specific cells.
Social media isn't always accurate — Reddit's
targeting of the wrong suspect
in the 2013 Boston bombings is one cautionary example — but the barrage of data produced by Twitter and Facebook can be immensely
useful to emergency responders and researchers studying crises, and point to innovative crisis management.
More importantly, within the afflicted groups, both the mice and humans had similarly poor performance
in the hidden
target trials, making the Morris Maze Test a
useful tool for comparing our two species, the researchers say.
The observed increase
in the biomarker for itch (IL - 31)
in skin points to another
useful therapeutic
target for children.
This pathway is currently the focus of development of
targeted therapy for moderate - to - severe eczema, suggesting that these same agents being tested
in adults could also be
useful in young children.
This means that
in a world where antibiotic resistant bacteria is becoming a real problem, this information could be very
useful in creating new methods to
target harmful bacteria.
The drug that they have developed appears to
target cancer stem cell activity, which suggests it will prevent metastatic recurrence and be
useful in combatting drug resistance.»
These bubbles are thousands of times smaller than the tip of a pencil lead — so small they are invisible even under most optical microscopes — and their stability makes them
useful in a variety of applications, from
targeted drug delivery to water treatment procedures.
A technique using anesthesia - containing nanoparticles — drawn to the
targeted area of the body by magnets — could one day provide a
useful alternative to nerve block for local anesthesia
in patients, suggests an experimental study
in the April issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).
Targeted interventions for mood instability may also be
useful in patients who do not have a formal affective disorder.
In some cases, the off -
target effects of a drug could make it
useful for treating conditions other than the one for which it was originally developed.
«These different stages represent potential
targets for limiting or stopping the progression of the disease, and may also be
useful for blocking abnormal bone formation
in other conditions besides FOP.
These findings suggest that miR135 could be a
useful therapeutic molecule — both as a blood test for depression and related disorders, and as a
target whose levels might be raised
in patients.
Gene therapy could
target the production of IL - 6
in bone marrow without suppressing its
useful effects elsewhere
in the body.
For example, many of the genes
in the new networks are related to cancer, suggesting that certain cancer treatments that
target these genes might also be
useful to treat ASD.
We now have early evidence that
targeting DNA methylation may be
useful in restoring p16, and thereby arresting tumor growth.
Ben Stanger, MD, PhD, a professor
in the division of Gastroenterology, and first author Ravi Maddipati, MD, an instructor
in the division of Gastroenterology, say that these results may prove
useful in designing better
targeted therapies to stop tumor progression and provide an improved non-invasive method for detecting early disease states
in this highly lethal cancer.
Because they are portrayed more frequently
in YouTube videos, it may be
useful to
target men with future interventions debunking alcohol - related myths propagated on social media.»
Sodium MRI has great potential to be a
useful new high and ultra-high field scanning
target in the future.
Dr. Dong said the findings have significant implications
in the prevention and treatment of type 2 diabetes and could prove to be
useful targets for modulation of insulin sensitivity and glucose homeostasis and as a
target for therapeutic agents to increase liver function to prevent diabetes.
These findings suggest that
targeting NFAT activity might be a
useful way to ameliorate lung injury
in severe streptococcal infections.