Sentences with phrase «uses model organisms»

My group uses model organisms to understand the molecules that control the tempo of development.

«I had been thinking about model organisms for a very long time in academia, and when I started to realize that there were all these people clamoring for their rare diseases I thought, «Why aren't people using model organisms to study them?

Using the model organism, Caenorhabditis elegans, the researchers identified over 400 new mRNA editing sites — the majority regulated by ADR - 1 — and declared the protein the first global regulator of RNA editing.

Knowing these larvae respond to odors but not fully understanding the process by which they make decisions via olfactory cues, scientists at UC Santa Barbara are using this model organism to study brain function as it relates to behavior control.

Scientists use model organisms to study critical biological processes, but Egan said the study of nonmodel organisms is often the key to ecological questions, including those related to how the environment influences natural selection and speciation.

Researchers at the Universities of Edinburgh and NYU Langone Medical Center have developed two types of molecular switch that work in yeast, a commonly used model organism.

He has made fundamental contributions to our understanding of vertebrate developmental biology and microRNA - based gene regulation using the model organism zebrafish.

A full realisation of the medical potential of stem cells for human health will likely depend on a reinforcement of, and development of a whole continuum of studies ranging from those in vivo using model organisms, to cell - based therapies in the clinic.

One reason why we know little about this process of telomerase silencing is because specific telomerase regulation naturally occurs only in human cells but not in mouse cells, a widely used model organism where telomerase is active in all cell types.

This network funds pilot studies to expedite collaboration between the two groups, conduct model organism - based functional studies of disease gene variants, and develop new therapeutic strategies using model organisms.

In my laboratory we are exploring this question using the model organism C. elegans.

Not exact matches

Dennis has a PhD in genetics / developmental biology from the University of British Columbia and a special interest in studying pattern formation and cell - cell communication during tissue development using fruit flies as a model organism.

While tomatoes have been regularly used as a model organism to study the effect of climate in fruit ripening, its commercial history is a chequered one.

In collaboration with Synchrotron Oxford, the University of East Anglia and the University of California, the researchers, using a commonly - found member of human gut microbiota called Ruminococcus gnavus as a model organism identified carbohydrate binding modules with the ability to bind to mucus.

Protein misfolding and aggregation had been identified as a major factor in mad cow disease, and research using yeasts as model organisms played a large role in those findings.

«The whole value of model organisms is that they are lean and mean,» so once he has established his proofs of principle, ideally he will be able to use a matrix approach to efficiently tackle many rare diseases simultaneously.

She did her master's degree research project at the Institute of Biochemistry and Biophysics (IBB), also in Warsaw, looking at the effect of genetic mutations on the function of an enzyme involved in the biosynthesis of heme, using Saccharomyces cerevisiae as a model organism.

The research team, led by Bosch, use the freshwater polyp Hydra as the model organism to elucidate the fundamental principles of nervous system structure and function.

Using the freshwater polyp Hydra as a model organism, the Kiel - based researchers and their international colleagues investigated how the simple nervous system of these animals interacts with the microbiome.

Cellulose fibers produced by the model organism Komagataeibacter (Gluconacetobacter) xylinus are very similar to those found in plants (1) and are increasingly used in biotechnology and nanotechnology (2, 3).

As a proof - of - concept, the researchers cloned more than 3,000 DNA fragments from E. coli bacteria, commonly used as a model organism with a catalogued genome sequence available.

He presented his idea one day to a roomful of about 30 colleagues at Yale's «Worm Meeting,» the weekly gathering for researchers studying C. elegans, the lowly nematode widely used as a model organism in developmental biology.

Drosophila melanogaster, a dipteran (two - winged) insect, is the species of fruit fly that is commonly used in genetic experiments; it is among the most important model organisms.

Now that the team has generated the tools necessary to rapidly manipulate killifish, the model organism can be used to screen for genes and drugs that slow or reverse aging and age - related diseases.

Species distribution or crop - niche modeling is another sophisticated technology that archeologists use to predict where plants and other organisms grew well in the past and where they might be useful today.

«Using yeast as a model organism, we studied the Tup1 protein, a negative regulator of gene expression,» says Biology Professor Emanuel Rosonina, adding, «This protein binds to some genes and blocks their expression, helping to ensure genes that shouldn't be turned on remain inactive.»

The fruit fly Drosophila melanogaster is a heavily studied model organism often used to examine genetic changes during evolution.

In the decades that followed, Brenner helped launch the concept of using complex model organisms to figure out how genes function.

Replacement alternative methods include the use of data concerning the physicochemical properties of chemicals; predictions based on structure - activity relationships, including the use of qualitative and quantitative mathematical models; the biokinetic modelling of physiological, pharmacological, and toxicological processes; experiments on lower organisms not classed as?

For this reason, the zebrafish is now used as a model organism by scientists around the globe.

Using machine learning, Chris Wiggins hopes to develop models that can predict how all of an organism's genes behave under any circumstance - and thereby explain precisely why some cells become sick or cancerous

Curran and his colleagues tweaked the amount of Maf1 in C. elegans, a transparent worm often used as a model organism by biologists.

This unicellular fungus is often used as a model organism, because it works as a mammalian cell, though it is easier to handle.

«Like many labs, we use C. elegans — a tiny roundworm — as a model organism to reveal important lessons about aging and autophagy,» explains Hansen.

When projects on the scale of a nuclear power station or THORP are concerned, or the release of genetically modified organisms into the environment, to give another example, it is not possible to model them fully in the laboratory using traditional trial - and - error methodology.

The Bone Densitometer will allow astronauts to examine bone density of model organisms in space through the use of Dual - Energy X-ray Absorptiometry (DEXA) technology.

His lab is continuing to use the zebrafish as a model organism, but Junker also sees great potential in applying the technique to human organoids.

For example, if you want to transpose the function of a protein in a model organism to the corresponding human protein, you can make use of orthology to detect the right protein.

Different model organisms like the fruit fly Drosophila melanogaster are used for their research, aimed at decoding the principles of stem cell control with the aim to also apply them to higher forms of life and eventually humans.

The research team conducted experiments on the roots of Arabidopsis, a plant often used as a «model organism» in plant biology and had its genome fully sequenced in 2000.

A research group from the University of Seville has revealed the role that the protein Rrm3 plays in the repair of breaks that occur during the replication of DNA, by using the yeast Saccharomyces cerevisiae as a model organism.

With his usual style and wit, he discusses the use of methods and models adapted from physics and mechanical engineering to explore how organisms move and function.

During panel discussions Sept. 18 at 6, 7 and 8 a.m. PDT (9, 10 and 11 a.m. EDT), scientists and researchers will discuss the various science and research studies, including RapidScat, 3 - D printing in Zero - G, technology to measure bone density, and model organism research using rodents, fruit flies and plants.

Using the Drosophila melanogaster fruit fly as a model organism, the team led by Prof. Dr. Ingrid Lohmann at Heidelberg University's Centre for Organismal Studies was able to show how a special developmental gene from the Hox family influences germline stem cells.

The researchers used proteins from baker's yeast — a model organism for the more complex systems found in animals.

«Using the anti-cancer drug and a replication inhibitor, hydroxyurea, in the model organism Saccharomyces cerevisiae, we observed that double strand breaks preferentially occurred at hydroxyurea - induced genes,» said Feng.

Using a novel method they developed to map chromosome breaks in a model organism, the budding yeast, Wenyi Feng, Ph.D., of Upstate Medical University and her colleagues have discovered new information as to how and where chromosome fragile sites can occur in human DNA.

The researchers studied this adaptive bacterial life cycle using Bacillus subtilis as a model organism.

NASA will host a prelaunch panel discussion at 8 a.m. PDT Sept. 18, at the agency's Kennedy Space Center in Florida, featuring scientists and researchers who will discuss various science and research studies, including the four Ames - supported payloads to study model organism research using yeast, rodents, fruit flies and plants.

Using genetic models in a variety of organisms — yeast, nematodes, fruit flies, zebrafish — PLab aims to identify candidate treatment compounds for each disease, which can then be refined and taken to the clinic with partner companies.