Sentences with phrase «uses of stem cell therapy»

Undeterred, advocates for the immediate use of stem cell therapy in human athletes point to successes with racehorses as the best evidence that the treatment works.

The possible use of stem cell therapy for treatment of Parkinson's disease is long awaited and much needed (2 December,...

Recent advances have raised expectations that diseases of the CNS may be improved by the use of stem cell therapies.

Ole Isacson, Dr Med Sci, director of the Neuroregeneration Research Institute at McLean Hospital and one of the world's preeminent experts in the use of stem cell therapies to treat neurodegenerative diseases such as Parkinson's disease...

Not exact matches

Venter reiterated this sentiment: «Using the combined power of our core areas of expertise — genomics, informatics, and stem cell therapies, we are tackling one of the greatest medical / scientific and societal challenges — aging and aging related diseases,» he said in a statement.

That means that the stem - cell therapies have to be converted into whatever cell they're meant to be (heart - muscle cells, neurons, and so forth) before going into the body, rather than using different kinds of stem cells to treat the condition.

«Using the combined power of our core areas of expertise — genomics, informatics, and stem cell therapies, we are tackling one of the greatest medical / scientific and societal challenges — aging and aging related diseases,» said Dr. Venter.

If ESCR using «excess» embryos from IVE» continues, the next step will likely be the pursuit of such «therapeutic» cloning — the creation of embryos through somatic cell nuclear transfer (SCNT) to provide individually tailored stem cell therapies.

Researchers at Rush University Medical Center are exploring a new therapy using stem cells to treat spinal cord injuries within the first 14 to 30 days of injury.

A team of researchers at the Stanford University School of Medicine has used a gene - editing tool known as CRISPR to repair the gene that causes sickle cell disease in human stem cells, which they say is a key step toward developing a gene therapy for the disorder.

Dr. Zubair, medical and scientific director of the Cell Therapy Laboratory at Mayo Clinic in Florida, says the experiment will be the first one Mayo Clinic has conducted in space and the first to use these human stem cells, which are found in bone marrow.

Scientists use mathematical modeling to simulate human mesenchymal stem cell delivery to a damaged heart and found that using one sub-set of these stem cells minimises the risks associated with this therapy.

Researchers, led by Joshua Mayourian at the Icahn School of Medicine at Mount Sinai, used mathematical modeling to simulate electrical interactions between these stem cells and heart cells to develop insight into possible adverse effects, as well as to hypothesize new methods for reducing some potential risks of this therapy.

On 13 April, the Texas Medical Board voted to accept rules intended to give doctors «a reasonable and responsible degree of latitude» in using experimental stem cell therapies.

Realistic stem cell therapies to replace diseased or damaged tissue may still be years away, but researchers have uncovered a promising new use for these undifferentiated cells: they can be programmed to become patient - specific laboratory models of inherited liver disease.

The act of reprogramming cells to make them as capable as ones from embryos apparently can result in aberrant cells that age and die abnormally, suggesting there is a long way to go to prove such cells are really like embryonic stem cells and can find use in therapies.

«The next step of progress is to use this knowledge to decipher what potential impact the genetic variants can have on the health of individuals, when we conduct health - related research,» added Professor Michael Pepper, Unit Director of the South African Medical Research Council's (SAMRC) Stem Cell Research and Therapy Unit, Faculty of Health Sciences at the University of Pretoria.

These include the ability to bring new, innovative products to the market; progress in oncology, such as the approval of Genentech's drug Avastin for breast cancer and advances in the use of gene therapy, despite some setbacks; continuing progress in research on stem cells; the emergence of treatments for previously untreated diseases; and solutions for food and fuel shortages, such as biocrops and biofuels.

«The discovery of the novel progenitor represents a fundamental advance in this field and potentially to the liver regeneration field using cell therapy,» said the study's senior author, Valerie Gouon - Evans, PharmD, PhD, Assistant Professor, in the Department of Developmental and Regenerative Biology, Black Family Stem Cell Institute, at the Icahn School of Medicine at Mount Sicell therapy,» said the study's senior author, Valerie Gouon - Evans, PharmD, PhD, Assistant Professor, in the Department of Developmental and Regenerative Biology, Black Family Stem Cell Institute, at the Icahn School of Medicine at Mount SiCell Institute, at the Icahn School of Medicine at Mount Sinai.

The immediate payoff was a commercialization deal in age - related macular degeneration in which Pfizer became the first big pharma company to make a move into the use of embryonic stem cells as the basis for a tissue regeneration therapy.

In a last - ditch effort to save a dying 7 - year - old boy, scientists have used stem cells and gene therapy to replace about 80 percent of his skin.

«It is disconcerting that the Italian Senate has passed amendments that permit the use of unproven stem cell therapies without proper vigilance or proper experiment, reclassifying them as transplants,» commented Bianco.

«With the rise of new and unproven stem cell treatments, the NFL faces a daunting task of trying to better understand and regulate the use of these therapies in order to protect the health of its players,» said Kirstin Matthews, the Baker Institute fellow in science and technology policy and an expert on ethical and policy issues related to biomedical research and development.

An international group of leading stem cell researchers has issued a statement that specifies concerns about the development and use of unproven stem cell therapies.

We have found that exosomes and the cargo they contain are crucial mediators of stem cell - based heart regeneration, and we believe this might lead to an even more refined therapy using the «active ingredient» instead of the entire stem cell,» said Eduardo Marbán, MD, PhD, director of the Cedars - Sinai Heart Institute and a pioneer in developing investigational cardiac stem cell treatments.

Scientists used a combination of stem cells and gene therapy to repair the damage.

The authors conclude that mesenchymal stem cell therapy has great potential as a therapeutic option in feline disease, but that many questions about the logistics of its use remain to be answered.

Results from a clinical trial investigating a new T cell receptor (TCR) therapy that uses a person's own immune system to recognize and destroy cancer cells demonstrated a clinical response in 80 percent of multiple myeloma patients with advanced disease after undergoing autologous stem cell transplants (ASCT).

Three months after the Chinese health ministry ramped up its efforts to enforce a ban on the clinical use of unapproved stem - cell treatments, a Nature investigation reveals that businesses around the country are still charging patients thousands of dollars for these unproven therapies.

«Long - term remissions in some patients after stem cell transplants from donors have been observed, but treatment - related toxicity limits the widespread use of this therapy.»

The researchers, who are based at the Academy of Scientific & Innovative Research, located at the CSIR - Indian Institute of Chemical Technology, Hyderabad, India, hope that the technique can enhance regenerative therapy for conditions like chronic wounds, where harsh inflammation in the wound can kill the cells used in regenerative stem cell treatments.

Unlike embryonic stem cells, the use of adult stem cells in research and therapy is not controversial because the production of adult stem cells does not require the destruction of an embryo.

Ploegh envisions the technique being used to create a new type of personalized therapy in the future — your own cells could be isolated, used to create stem cells that differentiate into erythroblasts, genetically modified to carry a molecule, and reinjected into your body.

With these findings, Helmholtz Zentrum München scientists have discovered key molecular functions of stem cell differentiation which could be used for beta cell replacement therapy in diabetes.

Fischer, in 2000, reported demonstrating the clinical efficacy of gene therapy for the first time, using blood stem cells to treat a fatal genetic disorder called X-linked severe combined immunodeficiency.

In a new study scheduled for publication in The Journal of Pediatrics, researchers evaluated the safety and feasibility of using stem cell therapies on very preterm infants to prevent or treat BPD.

This is both a useful tool for giving us a better understanding of the genetic and epigenetic program controlling the self - renewal of stem cells, and on a practical side, it could allow us to inexpensively produce large numbers of immune cells, which could then be used for regenerative medicine or immune therapy.»

In a bid to counteract some of the hype, scientists came to Rockefeller University here last week for a 1 - day conference that offered a clear - eyed look at obstacles that will have to be surmounted before human embryonic stem (ES) cells can be used in therapy.

With so much work needed in studying the nature of stem cells and using them to study disease processes, therapies based on ES cells seem very far down the line, noted Lorenz Studer of Memorial Sloan - Kettering Cancer Center in New York, who pointed out that so far there have only been two published papers on therapeutic cloning, both of them in mice.

Past clinical trials of stem cell therapies for chronic stroke patients used cells derived from tumors in humans and brain tissue from fetal pigs.

The safe use of a stem - cell - based therapy against brain metastasis would require preventing the engineered cells from persisting within the brain, where they could affect normal tissue and possibly give rise to new tumors.

«It suggests to us that targeting the pathways used in regulating cell fate decisions — how stem cells choose between cell proliferation and differentiation — could be a more effective way of halting tumours in their tracks and lead to potential new therapies.»

After hearing a brief explanation that laid out the different sources of stem cells (but left undiscussed their current uses or future potential for therapy), the respondents offered a slightly more nuanced set of views, and only a slight majority (52 %) supported embryonic stem cell research.

Paving the way for stem cell therapy, the first clinical trials using iPSCs was conducted by Masayo Takahashi, MD, PhD, of the RIKEN Centre for Developmental Biology in Japan.

I - Stem, the Institute for Stem cell Therapy and Exploration of Monogenic Diseases, has signed an agreement with Swissbased healthcare company Roche to use I - Stem's technologies in discovering novel therapies to treat devastating central nervous system (CNS) diseases such as Alzheimer's, schizophrenia, depression and anxiety.

For the first time, through the use of human embryonic stem cells (hES) sourced from pre-implantation diagnosis, researchers from Inserm's Institute for Stem Cell Therapy and Exploration of Monogenic Diseases (I - Stem) have successfully identified the previously unknown mechanisms involved in Steinert» disease, also known as type 1 myotonic dystrostem cells (hES) sourced from pre-implantation diagnosis, researchers from Inserm's Institute for Stem Cell Therapy and Exploration of Monogenic Diseases (I - Stem) have successfully identified the previously unknown mechanisms involved in Steinert» disease, also known as type 1 myotonic dystroStem Cell Therapy and Exploration of Monogenic Diseases (I - Stem) have successfully identified the previously unknown mechanisms involved in Steinert» disease, also known as type 1 myotonic dystroStem) have successfully identified the previously unknown mechanisms involved in Steinert» disease, also known as type 1 myotonic dystrophy.

The exploration of the therapeutic potential of stem cells requires the characterization of their biological properties, the deciphering of the mechanisms that underlie their pluripotency and their capacity at differentiation, by the understanding of the signals that direct their fate towards discrete cell phenotypes... Their therapeutic use requests further, in particular in the case of substitutive therapies, the analysis of their capacities of integration in injured adult tissues and of their potential tumorigenicity, as well as the development of original ways of delivery.

A full realisation of the medical potential of stem cells for human health will likely depend on a reinforcement of, and development of a whole continuum of studies ranging from those in vivo using model organisms, to cell - based therapies in the clinic.

Often the feasibility of using stem cells for regenerative therapies is limited by two factors: obtaining a significant number of cells and doing so in a relatively noninvasive manner.

The finding challenges the current course of research into muscular dystrophy, muscle injury, and regenerative medicine, which uses stem cells for healing tissues, and it favours using age - matched stem cells for therapy.