Sentences with phrase «using aneuploidy»

In the new study, published yesterday in PLOS Biology, Heitman and colleagues set out to explore whether genetically identical, unisexually reproducing C. neoformans cells were using aneuploidy to generate offspring that differed from themselves.

Not exact matches

Given the rapid succession of generations in yeast, we can use it as a model organism — and study the mechanisms of aneuploidy in much greater detail to find out whether we can derive from it new approaches for diagnosing and treating human diseases.»

Although Hunt stresses that no data clearly link BPA to human aneuploidy, she thinks the question deserves study because the compound is so widely used.

Until now, one of the only ways of screening eggs or embryos for aneuploidy was to use a technique called fluorescence in - situ hybridisation (FISH), in which specific chromosomes are stained with small pieces of fluorescent DNA to...

Using Plk4 overexpression (PLK4OE) during epidermal development, we assess the impact of centrosome amplification and aneuploidy on skin development and tumorigenesis.

Here we use two different mutant conditions to address the consequences of aneuploidy during tissue development and homeostasis in Drosophila.

Haplotype mapping of a diploid non-meiotic organism using existing and induced aneuploidies.

Using a series of genetically - matched euploid and aneuploid cell lines, we have demonstrated that aneuploidy can paradoxically function as a barrier to tumor growth.

Each mouse autosome is present in at least two Robertsonian chromosomes, so that these stocks can be used to generate specific aneuploidies for each of the 19 mouse autosomes.

Results: We validate our approach using data with known copy number, identifying the vast majority of aneuploidies with a low rate of false discovery.

However, detection of aneuploidies using conventional single - cell DNA - sequencing protocols is slow and expensive.

Today academic institutions and teaching hospitals across the country receive federal or private grants to support groundbreaking research using human fetal tissue on a wide range of conditions including diabetes, Parkinson's disease, Alzheimer's disease, spinal cord injuries, hemophilia, leukemia, sickle cell anemia, cortical blindness, fetal aneuploidy, ALS, and others.