Sentences with phrase «using cell»

We are using biochemistry and genetics to identify the proteins that enable neurite - specific neuropeptide localization and using cell - type - specific genetic manipulations to disable that machinery and thereby probe the behavioral function of extra-synaptic peptide signaling in specific circuits.

In a study using human muscle tissue, scientists in Children's Stem Cell Research Center - led by Johnny Huard, PhD, and Bruno Péault, PhD - isolated and characterized stem cells taken from blood vessels (known as myoendothelial cells) that are easily isolated using cell - sorting techniques, proliferate rapidly and can be differentiated in the laboratory into muscle, bone and cartilage cells.

We've really done a lot of manipulations using cell culture.»

The selection was furthermore based on morphological characteristics, widespread use and multitude of publications using these cell lines.

CHIP — quantitative real - time fluorescence PCR (qPCR) was performed using Cell Signaling SimpleChIP Plus Enzymatic Chromatin IP Kit (# 9005) according to the manufacturer's instructions.

PHILADELPHIA — In preclinical studies using cell models that mimicked liver cells of patients with the rare disease Friedreich's ataxia (FA), a widely used cholesterol - lowering drug increased a precursor of HDL (high - density lipoprotein), the «good cholesterol,» according to new research published in PLOS One from the Perelman School of Medicine at the University of Pennsylvania.

The method goes beyond what previous mathematical models were capable of by applying evolutionary information and using cell - based data.

Previous work has given insights into the mechanistic pathways leading to small molecule sequestration in membrane - free coacervate protocells; successfully demonstrated the use of liquid - liquid phase separated micro compartments for protein expression using cell free expression systems; exploited microfluidics for the high throughput formation of stable, monodisperse microdroplets; and integrated two contrasting modes of protocell construction to produce a novel hybrid model based on fatty acid membrane - bound coacervate micro-droplets.

Reduced contraction of skin equivalent engineered using cell sheets cultured in 3D matrices.

However, using these cell lines it should be possible to determine in detail how the defects arise (which is difficult in patients), and perhaps how to alter the segregation of mutant versus normal mtDNA during cell division to eventually lessen the burden of abnormal mitochondria function.

This research has been suggested before using cell cultures and in artificially aged mice, but this is the first time that a naturally - aging model has been used.

During the ensuing infection, it makes many copies of its genetic material, using the cell's machinery, and this reassembles into many more virus particles that are then released to infect more cells.

Using cell culture and laboratory mouse experiments, the researchers showed that the enzyme, aldose reductase, is essential to a process known as goblet cell metaplasia that is seen in both asthma and COPD.

Retinal cell classes were identified based on their morphology, location within the retina, and using cell class specific markers (Figures 5 and S2, S3, S4, S5, S6).

To verify that the individual cells they picked were pure, the researchers cultured them for several days to determine, using cell markers, whether they formed mature HSCs.

In other studies, however, using cell lines either in vivo or in vitro suggest that the alpha2 beta1 integrin may serve to enhance metastasis to different organs.

Using cell culture assays and genetically modified mice, we identified a number of signaling proteins that participate in muscle plasticity.

We are evaluating the therapeutic potential of interneuron - based interventions by using cell - based therapy and pharmacology.

Second, law enforcement officials may use the stingray to target a specific individual who is using a cell phone, but these officials do not know the cell phone number.

Then the researchers took the study outside the lab, asking participants to record their own emotions and the emotions of their partners six times a day for two weeks using a cell phone.

Vittoria Colizza, who organized the ESOF session and is head of computational epidemiology at the ISI Foundation in Turin, Italy, says that using cell phones, RFID tags, and dollars bills represent a «new wave of research» in human mobility studies.

«Using this cell line allows us to separate 2 - cell - like cells from the ES cells in the culture by collecting the green cells which have entered the 2 - cell like state.

Communication using the cell's own language, and the cell's own speed.

This is because it takes customers completely away from using cell networks, which bring in a substantial chunk of carriers» profits.

We have been using cell culture models and zebrafish as an assay to determine the effects of BMP on signaling, but we also want to be able to understand what the effect of the mutation is in the tissue and organ systems.

Using cell phone data for transport planning and design would be an economical option that would offer round - the - clock availability and relatively easy access to broad samples.

They've shown that using a cell phone while driving poses the same relative risk as driving with a blood - alcohol level at the legal limit.

Catherine Wong, 16, from the U.S., has a project that focuses on using cell - phone networks to bring telemedicine to people who do not have easy access to doctors.

Using cell models and genetically engineered mice, the authors then could reproduce kidney disease changes upon expression of APOL1 gene variants, but the disease required the presence suPAR.

Using cell cultures, the research team also found two ways to prevent the toxicity caused by alpha - synuclein: gene therapy that forced the neurons to make more TOM20 protein protected them from the alpha - synuclein; and a protein that was able to prevent alpha - synuclein from sticking to TOM20 prevented alpha - synuclein's harmful effects on mitochondria.

Dr. Stoddart's main research focus is using autologous stem cells and gene transfer to repair musculoskeletal tissues using a cell therapy approach.

Passwords, gestures and fingerprint scans are all helpful ways to keep a thief from unlocking and using a cell phone or tablet.

Studies of IBD are typically performed using cell culture experiments or animal models, which don't mimic the precise conditions that occur in the gut of human patients.

The journal's home page explains that translational medicine «builds on basic research advances — studies of biological processes using cell cultures, for example, or animal models — and uses them to develop new therapies or medical procedures.»

Called «Hyper - Spectral Phasor» analysis, or HySP, it could even be useful for diagnosing and monitoring diseases by using cell phone images.

But you can still see that from the mean averages between all three modes of conversation, using a Bluetooth you only crashed 4.04 times in a lap, but while using the cell phone it was 5.04.

The laboratory process, described in the journal Scientific Reports, entails genetically modifying a line of human embryonic stem cells to become fluorescent upon their differentiation to retinal ganglion cells, and then using that cell line for development of new differentiation methods and characterization of the resulting cells.

«What we've achieved with MOPID is the design of a polarized microscope platform using a cell phone, which can detect birefringence in histological specimens infected with the malaria parasite,» Coté says.

«Our ambition is to simplify drug discovery — by using the cell's own metabolites as drug candidates,» Dalby says.

Using cell - based model systems and Drosophila, they found CRMP1 overexpression reduces hungtingtin aggregation and cellular toxicity, while reduced CRMP1 results in increased aggregation and toxicity.

First, the research demonstrates that RB status can be tracked using cell - free DNA samples, an approach referred to as «liquid biopsy,» in prostate cancer patient samples.

«The discovery of the novel progenitor represents a fundamental advance in this field and potentially to the liver regeneration field using cell therapy,» said the study's senior author, Valerie Gouon - Evans, PharmD, PhD, Assistant Professor, in the Department of Developmental and Regenerative Biology, Black Family Stem Cell Institute, at the Icahn School of Medicine at Mount Sinai.

In preclinical studies using cell models that mimicked liver cells of patients with the rare disease Friedreich's ataxia (FA), a widely used cholesterol - lowering drug increased a precursor of HDL (high - density lipoprotein), the «good cholesterol,» according to new research published in PLOS ONE from the Perelman School of Medicine at the University of Pennsylvania.

This study identifies myomerger as a fundmentally required protein for muscle development using cell culture and laboratory mouse models.

The researchers also asked the parents to further specify whether their children were using cell phones, computers, video games or television during their technology time.

Troopers accuse Stein driving while intoxicated and crashing when he was using his cell phone to send a text message.

He wants to get his car back, he looks forward to using his cell phone again and he'd like to see his mother Aisha.

He wants to raid a fund for workers compensation, with the promise of reforming the entire system, and raise a small number of fees, including higher fines for texting or using a cell phone while driving.

«It's a dangerous world out there if you're using a cell phone.»

«Most people are using cell phones now anyway, and you load in your most commonly used numbers with the area code, so I don't think it will be that much of a big deal after a few months, everyone will get used to it,» said Stirpe.