Sentences with phrase «using cell transplants»

Previous researchers have also used cell transplant technologies to repair injured hearts, but these used CMs organized in two dimensions with a random, myofibril structure, which is different from natural heart tissue.

Not exact matches

Through CBR ®, we also help families to preserve newborn stem cells, which are used today in transplant medicine for certain cancers and blood, immune and metabolic disorders, and have the potential to play a valuable role in the ongoing development of regenerative medicine.

So hold on tight, I'm gonna share EVERYTHING I've learned so far about cord blood with you... starting with this enlightening link on the general benefits... including the fact that «To date it can treat more than 80 diseases using Haematopoietic Stem Cell (HSC) transplants, including leukemia, sickle cell anemia, and metabolic disorders.&raCell (HSC) transplants, including leukemia, sickle cell anemia, and metabolic disorders.&racell anemia, and metabolic disorders.»

Breech Twins and higher order multiples Previous CS Pre-Eclampsia Placenta praevia Cervical incompetence Previous late stillbirth Previous premature birth Grand multiparty Age under 18 Age over 35 Smoking Drug use Severe mental health issue Epilepsy Type 1 diabetes Type 2 diabetes Gestational diabetes Asthma GBS positive Abnormal antibodies Transplant recipient Congenital heart disease Known foetal abnormality Immunosuppressive medication MS Physical disability Intellectual disability Hypothyroidism Hyperthyroidism Previous shoulder dystocia Previous 3rd or 4th degree tear Sickle Cell anaemia BMI under 18 or over 35 at conception Previous massive PPH APH in current pregnancy HIV / AIDS Hepatitis B or C Active TB IUGR Oligohydramnios Polyhydramnios Child previously removed from custody because of abuse Uterine abnormalities such as uterine septum or double uterus Previous uterine surgery for fibroids Chronic renal problems Hypertension Auto immune condition Previous stroke or blod clot Cancer Domestic violence or abusive home Prisoners Homeless women

(borrowed from Dr Kitty) Breech Twins and higher order multiples Previous CS Pre-Eclampsia Placenta praevia Cervical incompetence Previous late stillbirth Previous premature birth Grand multiparty Age under 18 Age over 35 Smoking Drug use Severe mental health issue Epilepsy Type 1 diabetes Type 2 diabetes Gestational diabetes Asthma GBS positive Abnormal antibodies Transplant recipient Congenital heart disease Known foetal abnormality Immunosuppressive medication MS Physical disability Intellectual disability Hypothyroidism Hyperthyroidism Previous shoulder dystocia Previous 3rd or 4th degree tear Sickle Cell anaemia BMI under 18 or over 35 at conception Previous massive PPH APH in current pregnancy HIV / AIDS Hepatitis B or C Active TB IUGR Oligohydramnios Polyhydramnios Child previously removed from custody because of abuse Uterine abnormalities such as uterine septum or double uterus Previous uterine surgery for fibroids Chronic renal problems Hypertension Auto immune condition Previous stroke or blod clot Cancer Domestic violence or abusive home Prisoners Homeless women

Researchers used stem cells to create retinal pigment epithelium cells, which were transplanted into a patient's retina (left) in an area depicted by the black circle.

Richard Jones, M.D., professor and director of the Bone Marrow Transplant Program at Johns Hopkins, developed a now commonly used assay to study ALDH levels in individual cells.

A drug used to stop immune cells from gobbling up transplanted organs and bone marrow has been caught boosting the immune response to a virus in mice and monkeys.

«Using these new cells we might achieve organ acceptance in liver transplants, without touching the remaining immune system,» says co-author Luis Graca.

It is similar to how radiation and chemotherapy are used to «condition» patients for a bone marrow transplant, to improve engraftment of transplanted immune cells.

U.S. biotechnology company Circe Biomedical has had similar success, she said, showing in an ongoing clinical trial of a similar device using pig liver cells that six out of 36 patients have completely recovered without the need for transplant.

And early stage startup Neochromosome, which includes Boeke, intends to raise money to design synthetic chromosomes for medicine that could be used in an off - the - shelf universal cell line in cell therapies and transplants with minimal risk of rejection from the immune system.

Using cells from cadavers, doctors have been experimentally transplanting pancreatic islets into humans for decades, but as many as 60 percent of the transplanted islets die immediately because they are cut off from their blood supply and are killed by an immune response due to direct injection into the bloodstream, and those that survive the transplant usually die within several months.

«If you give patients immune cells to eradicate any remaining cancer cells that might be present,» he says, «those immune cells would not be prevented from doing their job by ongoing immune suppression drugs that are being used in patients treated with conventional transplant approaches.»

Weaver used diabetic mice to compare locations in the body where the transplanted cells could be placed.

Using the material and protein combination, the researchers evaluated multiple locations for implanting the islet cell clusters, the first time such a direct comparison of transplant sites has been made.

In a study recently published in the journal Nature Biotechnology, HSCI researchers at Harvard University and Massachusetts General Hospital (MGH), in collaboration with Boston Children's Hospital and Dana Farber Cancer Institute, have developed a non-toxic transplantation procedure using antibodies to specifically target blood stem cells in mice, an approach they hope will make blood stem cell transplants for these patients far less toxic.

(Mackenzie notes that it shouldn't be a problem for her strategy, because she plans to use the same kind of cells as bone marrow transplants, which haven't caused tumors.)

At the very least, Domínguez - Bendala hopes that they could use BMP - 7 to convert the other 98 per cent of donor pancreas cells into beta cells, which, he estimates, could potentially provide enough insulin - producing cells to transplant into seven people.

The mini-brain lasts about a month and it could be used to study a range of challenges in neuroscience including transplanting nerve cells that could help treat Parkinson's disease and studies on how adult nerve stem cells develop.

Researchers can create iPSCs from a patient's blood or skin cells, and use these patient - specific cells to study diseases or even create new tissues that could be transplanted back into the patient as therapy.

June 2008 was the first time a patient received a trachea transplant that made use of her own stem cells, in what was then the most advanced example of tissue engineering.

Others include transplanting so - called Schwann cells from peripheral nerves, using growth factors to stimulate nerve growth, and boosting the immune system in the damaged area (New Scientist magazine, 14 August 1999, p 36).

«It is disconcerting that the Italian Senate has passed amendments that permit the use of unproven stem cell therapies without proper vigilance or proper experiment, reclassifying them as transplants,» commented Bianco.

Transplants grown from stem cells in the lab can help replenish the blood and have been used to cure anaemia in mice.

New findings presented today indicate that with proper considerations, haploidentical (half - matched) transplants or transplants using cord blood cells can be viable, effective alternatives when a fully matched donor is not available.

The experiment Orwig has in mind is to use gene - editing technology to fix this flaw in the sperm - forming stem cells and then transplant them back into infertile mice, thereby demonstrating a potential treatment for male infertility.

THE world's first cloned human embryonic stem cells (hESCs) are here, but they can't yet be used to grow tissues for transplant because they have an extra set of chromosomes.

They're not developed enough to function as liver transplants, but the cell clusters do have important uses, says McGuckin.

As a result of the finding, researchers can also use Mauritian cynomolgus macaques to improve stem cell transplant outcomes for human patients with other blood - related conditions such as leukemia and sickle - cell disease.

Researchers have long used a different monkey species to research stem cell transplants, but that species» biological characteristics means it can't be reliably used to find good donor matches to mimic human stem transplants.

«Immunotherapy drug nearly eliminates severe acute graft - versus - host disease: Drug used to treat rheumatoid arthritis improves survival after hematopoietic stem cell transplant.»

Abatacept, when added to the standard drug regimen used to prevent GvHD, reduced the occurrence of acute, grade III - IV GvHD from 32 to 3 percent in pediatric and adult patients who underwent mismatched unrelated donor stem cell transplants to treat advanced cancer and other blood disorders.

Using cells from Down patients, scientists at the University of Massachusetts Medical School transplanted the XIST gene into that third copy.

Results from a clinical trial investigating a new T cell receptor (TCR) therapy that uses a person's own immune system to recognize and destroy cancer cells demonstrated a clinical response in 80 percent of multiple myeloma patients with advanced disease after undergoing autologous stem cell transplants (ASCT).

One uses primary hepatocytes obtained from livers donated for transplant; the second uses stem cells derived from human skin samples and guided into hepatocyte - like cells, Bhatia says.

In fact, in an ongoing clinical trial that is transplanting cells derived from induced pluripotent stem cells (iPSCs), gene sequencing is used to ensure the transplanted cell products are free of dangerous mutations.

But if he were performing a stem cell transplant for a cancer patient who also happened to have AIDS, he reasoned, then why not use stem cells with the CCR5 deletion?

Researchers report today that they grew prostate glands — important for reproduction in male mammals — in mice using a single stem cell transplanted from the prostates of donor mice.

«Long - term remissions in some patients after stem cell transplants from donors have been observed, but treatment - related toxicity limits the widespread use of this therapy.»

A new test may reveal which patients will respond to treatment for graft versus host disease (GVHD), an often life - threatening complication of stem cell transplants (SCT) used to treat leukemia and other blood disorders, according to a study led by researchers at the Icahn School of Medicine at Mount Sinai and published online today in the journal Lancet Haematology and in print in the January issue.

These so - called hematopoietic stem cells (from Greek meaning «to make blood») have been reliably used over the past 40 years to seed bone marrow transplants in the treatment of some cancers and immune disorders.

Atala wondered whether it would instead be possible to remove bladder cells from a patient and use them to grow a replacement organ, thus eliminating the risk of transplant rejection.

Adult stem cell treatments have been used for many years to treat successfully leukemia and related bone / blood cancers through bone marrow transplants.

This feature would be critical for clinical uses, such as transplanting stem cells — with their defects corrected — back into patients, but the researchers emphasize that years of further study remain before such treatments might be possible.

«Our results suggest that megakaryocytes might be used clinically to facilitate adult stem cell regeneration and to expand cultured cells for adult stem cell transplants,» says Meng Zhao, Ph.D., a postdoctoral fellow at Stowers and lead author on the study.

After two earlier published attempts that led to early - stage embryos but not confirmed embryonic stem cells, Mitalipov and colleagues took steps to preserve a protein complex believed to help primate eggs restructure transplanted DNA, and employed a new imaging system to observe the egg's chromosomes directly instead of by staining them or using ultraviolet light, which might damage DNA.

However, a new study published in Cell Reports provides clues about how the dose of transplanted bone marrow might affect patients undergoing this risky procedure, frequently used to treat cancer and blood diseases.

Using stem cells harvested from human bone marrow, researchers transplanted cells into mice modeling ALS and already showing disease symptoms.

They then transplanted progenitors of the inner ear cells into the inner ear of embryonic normal and Connexin 30 knockout mice using glass tubes with optimized tip sizes.