Sentences with phrase «using cytotoxic»

Autoimmune disorders, which may manifest with granulomas on both the skin and other surfaces, are treated corticosteroids to reduce any inflammation and with chemotherapy, using cytotoxic drugs to suppress the immune system.

Not exact matches

The compound (right panel) has a scorpion - like shape with two arms grabbing EphA2 - expressing cancer cells, and a tail (brown) constituted by a cytotoxic chemotherapeutic agent (paclitaxel used in this work).

The researchers demonstrate that the use of specific cytotoxic substances can also have a beneficial effect on the body's immune system.

This is the first trial reporting successful transplant in dyskeratosis congenita (DC) patients without the use of any radiation or conventional cytotoxic chemotherapy beforehand.

B cells, cytotoxic T cells, and helper T cells boost their use of glucose and increase their reliance on the glycolysis pathway to digest the sugar.

The CNIC research team generated cytotoxic memory T cells specifically targeting cancer by using different methods for vaccination with tumor antigens.

The laboratory of Vincenzo Cerundolo is the first group to report the use of tetrameric soluble class I / peptide complexes (tetramers) for the identification of tumor - specific cytotoxic T lymphocytes (CTLs), and subsequently shows that these novel reagents allow rapid and accurate analysis of human CTL responses.

This has resulted in accelerated research focused on understanding the mechanisms that tumors use to inactivate cytotoxic T cells and developing ways to overcome this inhibition (2, 3).

Chemotherapy for MDS patients involves the use of medicines that kill cells cancer cells called cytotoxic agents.

Positive clones were then differentiated using defined serum - free conditions outlined in Ng, et al [7], which overall gave rise to a CD45 + CD56 + CD117 − CD94 + population of cytotoxic NK cells [8] expressing the CD4 construct and other surface markers in a similar manner to peripheral blood NK cells.

Two cytotoxic conjugates STxB - doxorubicin (STxB - Doxo) and STxB - monomethyl auristatin F (STxB - MMAF) were synthesised using copper - free «click» chemistry.

This study illustrates the potential benefits of using GHRH antagonists for the treatment of cancers that are highly resistant to cytotoxic agents such as doxorubicin.

In fact at the doses used, the chemotherapy is not having direct cytotoxic activity, i.e. not directly killing the cancer cells.

The control of these conditions often involves the long - term use of corticosteroids and other drugs such as immunosuppressive or cytotoxic agents.

The study, published in the journal Aquatic Toxicology, is titled «Chemical dispersants used in the Gulf of Mexico oil crisis are cytotoxic and genotoxic to sperm whale cells.»