Sentences with phrase «using different antibodies»

However, «past studies performed with viruses containing higher populations of 7U viruses using other MAbs did not protect [non-human primates] against Ebola - Zaire, whereas studies using different antibodies containing high populations of 8U did.

Not exact matches

Bia was able to test the rice syrup alongside two different ELISA methods, one using the R5 antibody and the other using the Skerritt antibody (a monoclonal antibody for gluten detection that can be used on a variety of cooked and uncooked foods).

However, Schweitzer and her colleagues conducted a number of different tests on the T. rex sample, including testing for keratan sulfate using monoclonal antibodies, and compared their results to the same tests performed on known medullary tissue from ostrich and chicken bone.

In a study published in the May 29, 2014, edition of Molecular Ecology Resources, Duke researchers Peter Larsen, Ryan Campbell and Anne Yoder used high - throughput sequencing on sifaka blood samples to generate sequence data for more than 150,000 different sifaka antibodies — protective molecules that latch on to bacteria, viruses and other foreign invaders in the body and fight them off before they cause infection.

«We used two different antibodies — one of which has been in clinical trials for Alzheimer's — to neutralize the effects of amyloid - beta and showed that you're able to rescue changes in tau,» Young - Pearse said.

To investigate why checkpoint inhibitors so often stop working, Velculescu; Valsamo Anagnostou, M.D., Ph.D., instructor of oncology at the Johns Hopkins University School of Medicine; Kellie N. Smith, Ph.D., a cancer immunology research associate at the Johns Hopkins University School of Medicine; and their colleagues at the Bloomberg ~ Kimmel Institute for Cancer Immunotherapy studied tumors of four patients with non-small cell lung cancer and one patient with head and neck cancer who developed resistance to two different checkpoint inhibitors: a drug called nivolumab that uses an antibody called anti-PD-1, or nivolumab used alone or in combination with a second drug called ipilimumab, which uses an antibody called anti-CTLA4.

BI-1206 showed remarkable success in mice in overcoming resistance to monoclonal antibodies like rituximab, currently used to treat different types of lymphoma and leukemia.

Using this approach as a template, researchers could substitute other types of antibodies and vaccines to target different tumors.

The researchers harvested satellite cells from both healthy and injured muscle tissue of young mice and from healthy tissue of old mice; extracted these cells» DNA with the histone coatings intact; and used tagged antibodies targeting the different kinds of marks to find which spots on those histones were flagged with either «stop» or «go» signals.

By seeding elements with an assortment of antibodies, the device could be set up to capture several different cancer cells types using a single blood sample.

These neutralizing llama antibodies target different areas of the CD4 - binding site of the virus, therefore breadth and potency are increased when they are used in combination.

This antibody binds to the D664KW666 core 2F5 epitope but use entirely different germ line V genes from 2F5 and that are significantly less divergent than 2F5 from thei

They seek to improve and prolong the level of protection seen in RV144 by using an extra vaccine boost and different adjuvants that may increase and prolong antibody responses.

Once optimal detector gains were determined, an extensive brightness index of dyes was established on this instrument using sequential single staining of mouse splenocyte with 43 different antibody conjugates against mouse CD8a (53 - 5.8).

a) To measure the overlap coefficient of different antibody binding sites, the signals were separated from background using a brightness criterion and made binary.

Tissue microarrays are used to show antibody staining in samples from 144 individuals corresponding to 44 different normal tissue types, and samples from 216 cancer patients corresponding to 20 different types of cancer (movie about tissue microarray production and immunohistochemical staining).

The overall score encompass several factors: reproducibility of the antibody staining in different cell lines (and if signal strength correlates with RNA expression levels); assays for enhanced antibody validation by using antibodies binding to different epitopes on the same target protein (independent antibodies), by knockdown / knockout of the target protein (genetic methods) and by matching of the signal with a GFP - tagged protein (recombinant expression); experimental evidence for location described in literature.

During the 1980s, Marder led studies using antibodies and the technique of immunocytochemistry to reveal the presence of many different neuromodulators in nerve fibres around the STG of crabs, including serotonin, proctolin and GABA.

Annotated protein expression profiles are performed using single antibodies as well as independent antibodies (two or more independent antibodies directed against different, non-overlapping epitopes on the same protein).

Testing of 51 specimens from CFS patients and 56 matched and healthy controls from the US was performed independently in three laboratories for XMRV DNA by using several PCR tests and for anti-XMRV antibodies using different serological assays.

Using different mouse models of cancer, a therapy consisting of antibodies which block the PD - 1 / PD - L1 checkpoint to boost the ability of T cells to fight cancer cells was used in combination with anti-CD27 antibodies, which activate T cells via the receptor CD27.

The IME Molecular Biology Division has a long standing expertise in the expression of recombinant proteins like therapeutic antibodies and vaccines using different transient and stable plant - based systems.

The IME Molecular Biology Division has a long standing expertise in the expression of recombinant proteins like therapeutic antibodies and vaccines using different expression platforms.

«Now you have a way to test efficacy of future vaccines or future therapeutics, whether those therapeutics are drugs that exist already that could be used in a different way for a different purpose, or new classes of drugs such as antibody - based therapeutics that would be more specifically against Zika,» Diamond said.

A positive «+» antibody test as used in Idexx «4DX» test detects the presence of antibodies to the organism Ehrlichia canis and is consistent with your dog having been successfully transmitted one or more of the different Ehrlichia bacterial organisms from a protracted tick attachment.

A study performed by vaccine manufacturer Vanguard using a COMBINATION vaccine (one which contains several different vaccines) tested the efficiency of the vaccine in stimulating antibodies in an immune response.

The use of targeting antibodies against vascular endothelial growth factor (VEGF), a protein that promotes tumor growth and spread, plus chemotherapy has prolonged disease free survival in several different tumor types in man.

The different tests used to observe antigens and antibodies; immunoassay, Western Blot, and Eliza.