Sentences with phrase «using epidermal»

We are using the epidermal growth factor receptor (EGFR) as a model «endocytic system» to address these issues.

Among patients with advanced non-small cell lung cancer without a mutation of a certain gene (EGFR), conventional chemotherapy, compared with treatment using epidermal growth factor receptor tyrosine kinase inhibitors, was associated with improvement in survival without progression of the cancer, but not with overall survival, according to a study in the April 9 issue of JAMA.

Not exact matches

Researchers found that a combination of drugs — one targeting epidermal growth factor receptor (EGFR) and one targeting tumor necrosis factor (TNF)-- effectively blocks the cancer from using TNF as an escape route.

By using a range of tissue stains, they were able to assess levels of oestrogen receptor (ER), progesterone receptor (PR) and HER2 — human epidermal growth factor — in order to divide the samples into four subtypes.

Dr Dusko Ilic, leader of the team at King's College London, says: «Our new method can be used to grow much greater quantities of lab - grown human epidermal equivalents, and thus could be scaled up for commercial testing of drugs and cosmetics.

These keratinocytes were then used to manufacture 3D epidermal equivalents in a high - to - low humidity environment to build a functional permeability barrier, which is essential in protecting the body from losing moisture, and preventing the entry of chemicals, toxins and microbes.

Human epidermal equivalents representing different types of skin could also be grown, depending on the source of the stem cells used, and could thus be tailored to study a range of skin conditions and sensitivities in different populations.»

De Luca's team used a patch of skin a little bigger than a U.S. postage stamp from an unblistered part of the boy's groin to culture epidermal cells, which include stem cells that periodically regenerate the skin.

Researchers at The Rockefeller University have shown that a new technique using RNA interference is able to find genes that cause epidermal tumor growth in months rather than the decades it may take using traditional methods employing specially bred, genetically altered mice.

The drug Gefitinib is used to treat breast, lung, and other cancers by inhibiting epidermal growth factor receptor (EGFR) signaling, but it has only a limited effect on prostate cancer.

Then using heat lamps we're able to form blisters about the size of a dime,» explained Dr. Pandya, who traveled to China, India, and Detroit to be trained in non-cultured epidermal suspension grafting.

However, its use is hampered by the difficulty in supplying the amount of epidermal substitute needed in order to extend the application to all patients who may benefit from it.

Human epidermis has been produced in vitro for decades using adult epidermal stem cells from donors to provide cell therapy.

The first relies on the biochemical properties of a drug, while the second uses the antigen / antibody connection.26 The use of biotynilated - epidermal growth factor (EGFR) has been used to enhance the accumulation of cisplatin.27 Other local factors in the respiratory system influencing the absorption are the local transporters and genes.

Dual targeting of the epidermal growth factor receptor using the combination of cetuximab and erlotinib: preclinical evaluation and results of the phase II DUX study in chemotherapy - refractory, advanced colorectal cancer.

Transient assays were done in onion epidermal cells using the plant signal sequence fused to RBP and a GFP reporter (ssRBP - GFP fusion protein) with RBP fused to GFP as a control.

We are using live cell imaging, single cell analysis and gene editing to resolve the molecular determinants of human epidermal progenitor cell division outcomes (two progenitors, two differentiating cells or one or each) and the mode of cell division (maintenance mode vs repair mode).

Using Plk4 overexpression (PLK4OE) during epidermal development, we assess the impact of centrosome amplification and aneuploidy on skin development and tumorigenesis.

In the majority of studies of in vitro maturation (IVM), follicle stimulating hormone (FSH), luteinizing hormone (LH), estradiol and epidermal growth factor (EGF) are used as supplements.

Epidermal and cortical cells were measured individually in each plant along a single file and each analyzed time point using ImageJ software (http://rsb.info.nih.gov/ij/).

Clais also recommends using products containing «peptides and epidermal growth factor to stimulate collagen synthesis».

«Hydroquinone, retinoids, vitamin C, kojic acid, licorice extract, alpha hydroxy acids, azelaic acid or epidermal growth factor are all used to treat hyperpigmentation,» says Clais.

More than 3,000 years of recorded use, as well as modern clinical research in both humans and animals, suggest a wide range of potential applications for BLACK CUMIN SEED OIL ORGANIC - from helping to balance the gut microbiome to benefitting epidermal structure and appearance.

When used on the skin, alpha hydroxy acids help other cosmetic compounds penetrate more effectively and rapidly, absorbing deep into the skin's epidermal layers, for more effective and noticeable results.

Instead of aluminum starch or other anti-caking, mattifying components, we use bamboo silica: the protective layer in the epidermal cell walls of bamboo.

A series of studies at WALTHAM investigated if nutrients could be used to improve the epidermal barrier (Watson et al. 2006).

Next, seven of the 27 components (pantothenate, choline, nicotinamide, histidine, proline, pyridoxine and inositol) were retested using an in vitro trans - epidermal diffusion experimental model, providing a functional assessment of barrier properties (Watson et al. 2006).

Firstly, 27 nutritional components were screened in vitro for their ability to up - regulate epidermal lipid synthesis, using cultured canine keratinocytes (Watson et al. 2006).

Barrier function was measured throughout using trans - epidermal water loss (TEWL).