We are
using the epidermal growth factor receptor (EGFR) as a model «endocytic system» to address these issues.
Among patients with advanced non-small cell lung cancer without a mutation of a certain gene (EGFR), conventional chemotherapy, compared with treatment
using epidermal growth factor receptor tyrosine kinase inhibitors, was associated with improvement in survival without progression of the cancer, but not with overall survival, according to a study in the April 9 issue of JAMA.
Not exact matches
Researchers found that a combination of drugs — one targeting
epidermal growth factor receptor (EGFR) and one targeting tumor necrosis
factor (TNF)-- effectively blocks the cancer from
using TNF as an escape route.
By
using a range of tissue stains, they were able to assess levels of oestrogen
receptor (ER), progesterone
receptor (PR) and HER2 — human
epidermal growth factor — in order to divide the samples into four subtypes.
The drug Gefitinib is
used to treat breast, lung, and other cancers by inhibiting
epidermal growth factor receptor (EGFR) signaling, but it has only a limited effect on prostate cancer.
Dual targeting of the
epidermal growth factor receptor using the combination of cetuximab and erlotinib: preclinical evaluation and results of the phase II DUX study in chemotherapy - refractory, advanced colorectal cancer.