The DT40 evolution platform also supports
using gene conversion competent cells and homologous donor sequences as «pseudo genes» to evolve proteins of interest [24]--[25].
Not exact matches
But brain cells that had been created
using the direct
conversion technique had different patterns of
gene expression depending on whether they were created from young donors or older adults.
Using exome sequences from 3222 British - Pakistani individuals with high parental relatedness, we estimate a mutation rate of 1.45 ± 0.05 × 10 -LRB--8) per base pair per generation in autosomal coding sequence, with a corresponding non-crossover
gene conversion rate of 8.75 ± 0.05 × 10 -LRB--6) per base pair per generation.
The search engine recognizes common
gene identifiers; the
conversion to Affymetrix probe set IDs is done
using Ensembl BioMart [77] mappings.