Sentences with phrase «using gene therapy»

Lung Cancer Breakthrough A study published in the September, 1998 issue of Nature Medicine concerned a preliminary trial using gene therapy to treat lung cancer.

Summary: British doctors say they have achieved «mind - blowing» results using gene therapy to rid people of hemophilia A.

In the future, scientists may be able to modify human stem cell lines in the laboratory by using gene therapy or other techniques to overcome this immune rejection.

Over the past two decades, we've been told that a new age of molecular medicine — using gene therapy, stem cells, and the knowledge gleaned from unlocking the human genome — would bring us medical miracles.

But now a new approach promises to solve the problem by sidestepping the immune system altogether, instead using gene therapy to produce immune molecules that neutralize the virus.

This work, published in «Blood», was carried out by the CNIO Telomeres and Telomerase Group The treatment is based on the transport of the telomerase gene to the bone marrow cells using gene therapy, a completely new strategy in the treatment of aplastic anaemia

Conversely, by using a gene therapy approach to elevate progranulin levels, scientists were able to prevent these abnormalities and block cell death in this model.

Using gene therapy to increase the levels of progranulin in the mice, they reversed the symptoms.

His research focuses on understanding the role of inflammation in retinal degenerative diseases and seeks to target inflammatory pathways in these diseases using gene therapy.

Yesterday the BBC News and Guardian Newspaper reported that a team led by surgeon Professor Robert Maclaren at the Oxford Eye Hospital had succeeded in using gene therapy to halt the decline in vision in six patients with the progressive eye disorder choroideremia.

In 2013 scientists cured diabetes in dogs using gene therapy, the first time this was achieved in a large animalANCHOR.

«The current result suggests we may, in fact, be able to treat male infertility using gene therapy without worrying about those types of consequences.»

LA JOLLA, CA — Using a gene therapy delivery system developed in the laboratory of Inder Verma at the Salk Institute for Biological Studies, an international team of researchers successfully treated two...

Cure CMT4J is working toward a clinical trial using gene therapy to treat or cure CMT4J.

Also mitosens is nothing but using gene therapy to alter levels of specific proteins in a targeted fashion.

Since delivering GHK on its own appears to be beneficial, using gene therapy to reset GHK levels may restore some of this loss of regenerative capacity.

Using gene therapy to alter levels of specific proteins in a targeted fashion is an intermediary advance in medicine for age - related conditions.

FGF21: Overexpression of FGF21 occurs in the calorie restriction response, and when induced artificially using gene therapy it can extend life in mice.

An experimental protocol surgery using gene therapy to treat Alzheimer's disease is performed for the first time in the nation.

Researchers from the INc - UAB and the VHIR are the first to demonstrate that regulation of the brain's Klotho gene using gene therapy protects against age - related learning and memory problems in mice.

A few years ago, gene therapy researcher Ronald Crystal and colleagues at Weill Cornell Medical College in New York City successfully slowed LINCL in mice using gene therapy in the brain.

Using gene therapy to insert the gene, they expressed the synthetic gene in adult mice or in zebrafish embryos, and witnessed remote activation of neurons in the presence of a magnetic field through the altered behavior of the animals.

They found studies using gene therapy to promote the growth of «almost every different tissue» for use in regenerative surgery.

While the researchers can not yet point to a potential therapeutic application of their findings, identifying genetic changes that underlie MND is the first step in finding ways to manipulate these changes using gene therapy.

One solution might be, however, using gene therapy to stimulate such reprogramming of cells and thus to strengthen the self - healing abilities of the heart.

One study reported clinical benefits using gene therapy to regenerate joint cartilage in patients with rheumatoid arthritis.

Researchers from the Institute of Neurosciences at the Universitat Autònoma de Barcelona (INc - UAB) and the Vall d'Hebron Research Institute (VHIR) are the first to demonstrate that regulation of the brain's Klotho gene using gene therapy protects against age - related learning and memory problems in mice.

Woo and Ledley predict that clinical trials using gene therapy for metabolic disorders such as PKU could start within eight years.

2000 Announcement that two boys in France with X-linked SCID or «bubble boy» disease have been cured using gene therapy.

When they turned up the volume on the signal, using gene therapy techniques to increase the production of the signaling molecule, the mice with CMT regained muscle strength and their ability to walk improved significantly.

2009 Progression of the degenerative disease adrenoleukodystrophy is halted in two boys using gene therapy.

For more than two decades, researchers have explored using gene therapy, an experimental treatment, to replace the flawed gene with a healthy copy.

In a laboratory study in Oxford, researchers have shown how it might be possible to reverse blindness using gene therapy to reprogram cells at the back of the eye to become light sensitive.

Using gene therapy to insert the gene, they expressed the synthetic gene in adult mice or in zebrafish embryos, and witnessed remote activation of neurons the presence of a magnetic field through the altered behavior of the animals.

As the central nervous system is also a target of AAV vectors, Hélène Puccio and Patrick Aubourg's teams are investigating whether a similar approach using gene therapy could be as effective for the spinal cord and cerebellum as it is for the heart.

The scientists will now look into possible techniques to restore the function of pejvakin, particularly using gene therapy, which has already proved successful in conserving hearing in mice lacking in pejvakin, even when they are overexposed to noise.

Nirenberg is using gene therapy to sidestep damaged retinal cells to cure some forms of blindness.

However, they determined the blood levels of SMN are not altered when SMN levels are altered in motor neurons using a gene therapy approach delivered directly into the cerebrospinal fluid to target the central nervous system.

The SMA model pig was created using a gene therapy approach by knocking down the levels of pig SMN, followed by treatment with human SMN at early and late time points.

In the summer of 2015, a team at Boston Children's Hospital and Harvard Medical School reported restoring rudimentary hearing in genetically deaf mice using gene therapy.

This suggests that the time window for effectively treating USH1 syndrome using gene therapy may be larger than initially thought.»

That's the path pursued by GenVec, which wants to be the Rogaine of the ears, using gene therapy to regrow damaged hair cells.

We want to use gene therapy methods to protect people against HIV.

Has anybody ever done anything like this — used gene therapy to modify the immune system?

It's inevitable that people will use gene therapy for athletics.

Between 2008 and 2011 Jean Bennett, a neuroscientist at the University of Pennsylvania, and her colleagues used gene therapy to treat blindness in 12 adults and children with Leber's congenital amaurosis (LCA).

Nevertheless,» [the] study is very important because it demonstrates for the first time that we can use gene therapy to transform cells in the brain into ones that will secrete GDNF,» says Jeffrey Kordower, a professor of neurological sciences at Rush Presbyterian Medical Center in Chicago.

Given that artificial synthetic siRNAs can transfer through placenta, we can try to use gene therapy to treat fetal disease by maternal administration.»

«However, we don't use gene therapy to treat a toothache, we try to treat diseases which result in early death.»

Researchers at the University of Florida have successfully used gene therapy to treat patients with infantile onset Pompe disease, a progressive condition that severely compromises cardiopulmonary function in the first years of life.