Sentences with phrase «using gene therapy techniques»

When they turned up the volume on the signal, using gene therapy techniques to increase the production of the signaling molecule, the mice with CMT regained muscle strength and their ability to walk improved significantly.

Not exact matches

Using a new technique to deliver gene - therapy - like intervention directly where it's needed, researchers at Thomas Jefferson University successfully increased or decreased the muscle tone of the anal sphincter in appropriate animal models.

The scientists will now look into possible techniques to restore the function of pejvakin, particularly using gene therapy, which has already proved successful in conserving hearing in mice lacking in pejvakin, even when they are overexposed to noise.

The United States does not have an equivalent to HFEA, but FDA has said that anyone who wants to use the technique needs to apply to the agency for permission, because MRT is a form of gene therapy.

The Salk and TSRI scientists used a range of neuro - genetic, gene therapy, biochemical and structural biology research techniques to discover that the mutant GlyRS enzyme blocked molecular signals important for maintaining the health of motor neurons, the cells that carry messages from the brain to the muscles of the extremities.

Several biotechnology companies are using the gene editing technique in an effort to develop therapies for treating genetic diseases, including CRISPR Therapeutics, Intellia Therapeutics and Editas Medicine.

The researchers used the new technique to mutate the genes CXCR4 and CCR5, which encode receptor molecules that different strains of the HIV virus use to sneak in and infect immune cells and which have been targeted in previous cell therapy trials.

New delivery technique used to create a glowing adult mouse potentially opens the door for in vivo gene therapy

And doctors at the Great Ormond Street Hospital in London recently reported using a similar gene - editing technique called TALENs, which also recognizes and cuts precise DNA sequences, to engineer immune cells for a therapy that may have cured two infants of leukemia.

Many of the most promising approaches fall into four categories: the retinal prosthetic, gene therapy, stem cell treatments, and a technique that uses optogenetics, a way to engineer nerves to fire in response to bursts of light.

The idea there is that by identifying genes that cause, or contribute to glaucoma, and understanding what the protein products of those genes do, we can use new techniques to target those proteins to develop therapies that actually approach the actual disease mechanisms that cause the disease.

Many researchers in the past used the traditional gene therapy technique to treat mitochondrial disorders.

«We are really excited about this work because, short of correcting a faulty gene, protein - replacement therapy using mRNA is one of the most promising techniques we have at our disposal,» says senior author Inder Verma, professor of genetics and holder of Salk's Irwin and Joan Jacobs Chair in Exemplary Life Science.

In the future, scientists may be able to modify human stem cell lines in the laboratory by using gene therapy or other techniques to overcome this immune rejection.

Unlike most types of gene therapy, a longstanding approach that aims to alter only adult human tissues that die with the patient, the Crispr technique could be used to change human eggs, sperm and early embryos, and such alterations would be inherited by the patient's children.

Gene therapy, or an experimental technique that uses genes to treat disease, is currently being used to help patients who, even just a few years ago, had no options.

Almost 10,000 human adults have already had their genes altered through gene therapy techniques used to treat genetic diseases.