First, the destabilizing effects of VX - 770 on the corrected CFTR protein might be less robust in the human body than were the effects seen in lab tests
using human lung cells.
Not exact matches
Panoskaltsis - Mortari's team has been working on rebuilding
lungs and other parts of the respiratory system
using human stem
cells.
Using a mathematical model known as the Ising model, invented to describe phase transitions in statistical physics, such as how a substance changes from liquid to gas, the Johns Hopkins researchers calculated the probability distribution of methylation along the genome in several different
human cell types, including normal and cancerous colon,
lung and liver
cells, as well as brain, skin, blood and embryonic stem
cells.
Working in
human lung epithelial
cells, researchers
used a variety of techniques to show that flu infection increased activity of the PI3K and mTOR pathways and that BEZ235 restored PI3K and mTOR activity to pre-infection levels.
Using both fruit fly and
human lung cancer
cell lines, researchers targeted two of the most common genetic mutations associated with NSCLC — Ras and PTEN (P13K).
But with
humans, she is
using iPS
cells and has been working to develop the correct protocols to induce her stem
cells to differentiate into different kinds of
lung tissue.
Researchers developed a new type of
cell transplantation to treat mice mimicking a rare
lung disease that one day could be
used to treat this and other
human lung diseases caused by dysfunctional immune
cells.
By
using molecular genetic tools to reduce the amount of PC in
human lung cancer
cells, the team observed decreased
cell growth, a compromised ability to form colonies in soft agar (a gelatinous material specifically
used to grow bacteria and other
cells), and a reduced rate of tumor growth in mice.
It is surprising to find that a single gene (ESRP), through its ancestral biological role (
cell adherence and motility) has been
used throughout the animal scale for very different purposes: from the immune system of an echinoderm to the lips,
lungs or inner ears of
humans,» states professor Jordi Garcia - Fernàndez, of the University of Barcelona's Department of Genetics, Microbiology and Statistics and the IBUB.
Thomson's group created
human iPS
cells using fetal
lung cells and foreskin
cells with two of the same factors as Yamanaka, along with two different factors.
«The most important application of this patent will be the
use of our patented
human endoderm
cells to screen for agents that potentially affect endoderm differentiation, for example, to any of the important
cells derived from endoderm such as
lung, liver, intestine, pancreas, thymus, parathyroid and thyroid.»
To identify the JSRV receptor in
lung cells, Miller developed a system
using cultured hamster
cells that contain small pieces of
human DNA.
The first UK license for CRISPR / Cas9
use in editing genes in
human embryos was granted in 2016, xvii and CRISPR - edited
cells to treat
lung cancer were administered in the world's first
human trials for the technique by a Chinese group in late 2016.
Title of thesis: «Study of the pro-apoptotic effect of histones deacetylases inhibitors,
used alone and concurrently with chemotherapeutic agents, on
human lung cancer
cells».
San Diego, CA (March 31, 2009)-- Novocell, Inc., a stem
cell engineering company, today announced that it has received U.S. Patent 7,510,876 with claims covering
human definitive endoderm
cells, an essential
cell for generating not only pancreatic type
cells, which Novocell is developing for
use as a
cell therapy for diabetes, but also other endoderm lineage - derived tissues and organs such as
lungs, intestine, liver, thymus and thyroid.