Sentences with phrase «using human lung cells»

First, the destabilizing effects of VX - 770 on the corrected CFTR protein might be less robust in the human body than were the effects seen in lab tests using human lung cells.

Not exact matches

Panoskaltsis - Mortari's team has been working on rebuilding lungs and other parts of the respiratory system using human stem cells.
Using a mathematical model known as the Ising model, invented to describe phase transitions in statistical physics, such as how a substance changes from liquid to gas, the Johns Hopkins researchers calculated the probability distribution of methylation along the genome in several different human cell types, including normal and cancerous colon, lung and liver cells, as well as brain, skin, blood and embryonic stem cells.
Working in human lung epithelial cells, researchers used a variety of techniques to show that flu infection increased activity of the PI3K and mTOR pathways and that BEZ235 restored PI3K and mTOR activity to pre-infection levels.
Using both fruit fly and human lung cancer cell lines, researchers targeted two of the most common genetic mutations associated with NSCLC — Ras and PTEN (P13K).
But with humans, she is using iPS cells and has been working to develop the correct protocols to induce her stem cells to differentiate into different kinds of lung tissue.
Researchers developed a new type of cell transplantation to treat mice mimicking a rare lung disease that one day could be used to treat this and other human lung diseases caused by dysfunctional immune cells.
By using molecular genetic tools to reduce the amount of PC in human lung cancer cells, the team observed decreased cell growth, a compromised ability to form colonies in soft agar (a gelatinous material specifically used to grow bacteria and other cells), and a reduced rate of tumor growth in mice.
It is surprising to find that a single gene (ESRP), through its ancestral biological role (cell adherence and motility) has been used throughout the animal scale for very different purposes: from the immune system of an echinoderm to the lips, lungs or inner ears of humans,» states professor Jordi Garcia - Fernàndez, of the University of Barcelona's Department of Genetics, Microbiology and Statistics and the IBUB.
Thomson's group created human iPS cells using fetal lung cells and foreskin cells with two of the same factors as Yamanaka, along with two different factors.
«The most important application of this patent will be the use of our patented human endoderm cells to screen for agents that potentially affect endoderm differentiation, for example, to any of the important cells derived from endoderm such as lung, liver, intestine, pancreas, thymus, parathyroid and thyroid.»
To identify the JSRV receptor in lung cells, Miller developed a system using cultured hamster cells that contain small pieces of human DNA.
The first UK license for CRISPR / Cas9 use in editing genes in human embryos was granted in 2016, xvii and CRISPR - edited cells to treat lung cancer were administered in the world's first human trials for the technique by a Chinese group in late 2016.
Title of thesis: «Study of the pro-apoptotic effect of histones deacetylases inhibitors, used alone and concurrently with chemotherapeutic agents, on human lung cancer cells».
San Diego, CA (March 31, 2009)-- Novocell, Inc., a stem cell engineering company, today announced that it has received U.S. Patent 7,510,876 with claims covering human definitive endoderm cells, an essential cell for generating not only pancreatic type cells, which Novocell is developing for use as a cell therapy for diabetes, but also other endoderm lineage - derived tissues and organs such as lungs, intestine, liver, thymus and thyroid.
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