Sentences with phrase «using human samples»

Biobanco.pt is a national biomedical research infrastructure which aims at promoting national and international collaborative research projects using human samples, and the respective detailed clinical information Biobanco.pt commits to:

While a portion of this research was conducted in mice, the actual vaccine discovery experiments were performed using human samples, thus we believe the results will effectively translate to humans.»

«The idea will be to obtain oocytes and discarded embryos from IVF treatments in order to test this technology using human samples.»

Not exact matches

Rather than using the samples to screen for illegal drug use or preexisting medical conditions, TAT hopes to use its recently developed human - cloning technology to address a critical lack of available talent.

I. David Pierce, in his doctoral dissertation on cognition and theology, found that a sample of theologically liberal women were less inclined to use polar dimensions — such as «human effort» versus «divine power» or «instrumental» versus «relational» «-- than either a sample of men or a sample of theologically moderate or conservative women.

They rejected wood samples that could be hundreds of years older than their use by humans, for instance, in favor of short - lived pits and seeds.

This is a relatively non-technical description of how sampling was used to provide evidence in the trial of human rights violators.

If Rudenko confirms Clark's PCR tests using additional gene targets, and if Clark or Rudenko manage to grow Borrelia cultures out of human and lone star tick samples, then even the fiercest skeptics will have to recognize that Southern Lyme strains threaten human health, and that Lyme - like illness deserves Lyme - like treatment.

«Human beings make errors,» says Thompson, who was part of the defense team in the O. J. Simpson trial and has become — depending on your perspective — either a reasonable voice of caution about the use of DNA samples or a thorn in the side of forensics labs.

In the last four years, the U.S. - based Human Microbiome Project used genomic analysis to identify bacteria, viruses, fungi, archaea, and protozoa in the noses, gums, tonsils, genital tracts, and guts of 242 healthy Americans between the ages of 18 and 40; more than 11,000 samples were taken in all.

To more accurately reflect the mechanisms driving oligodendrogliomas, the researchers used RNA sequencing to study directly, on a single - cell level, gene expression in samples from six early - stage human tumors.

Senior author Madhav Dhodapkar, M.D., the Arthur H. and Isabel Bunker Professor of Medicine and Immunobiology, and chief of Hematology, said the study, using tissue and blood samples from humans and mice, shows that chronic stimulation of the immune system by lipids made in the context of inflammation underlies the origins of at least a third of all myeloma cases.

«I was carrying out sampling for my Masters Degree studies, but I had no idea that new dung beetles could be found in a forest that is disturbed by human activities, such as livestock grazing and land - use change,» recalls Moctezuma.

The new study, led by Johannes Krause, a geneticist at the Max Planck Institute for the Science of Human History in Jena, Germany, used next - generation sequencing methods to read stretches of any DNA present in a sample and fish out those that resembled humanHuman History in Jena, Germany, used next - generation sequencing methods to read stretches of any DNA present in a sample and fish out those that resembled humanhuman DNA.

At Cox's urging, Mash set out to conduct an independent study of ALS and Alzheimer's brains using samples from her own human brain bank.

By using a range of tissue stains, they were able to assess levels of oestrogen receptor (ER), progesterone receptor (PR) and HER2 — human epidermal growth factor — in order to divide the samples into four subtypes.

The researchers used source - tracking markers, a novel method Rose calls «CSI (Crime Scene Investigation) for water,» to sample 64 river systems in Michigan for E. coli and the human fecal bacteria B - theta.

But that study extracted ancient DNA from liver and intestinal samples using a method susceptible to contamination with modern human and bacterial DNA, Drosou's team argues.

«We also anticipate that the use of this method will be able to evaluate human serum samples to identify spectral signatures that can distinguish between Crohn's disease and ulcerative colitis.»

Using a mouse model of HSV - 1 as well as autopsied samples of human adult and fetal tissues, investigators from Dartmouth College's Geisel School of Medicine found that antibodies against HSV - 1 produced by adult women or female mice could travel to the nervous systems of their yet unborn babies, preventing the development and spread of infection during birth.

Baxter spokesman Christopher Bona said the samples were never meant for human or commercial use and blamed the incident on technical error.

In the new study, to test whether the same observation was true in humans, Dr. Rostami and colleagues tested blood samples of patients with MS who had not yet received therapy, and those currently being treated with INF - β, a commonly used therapy.

The next NASA mission planning to use an MMRTG is the Mars 2020 rover, due to be launched as part of NASA's Journey to Mars, to seek signs of past life on the Red Planet, test technology for human exploration, and gather samples of rocks and soil that could be returned to Earth in the future.

Under the new guidelines, researchers wishing to use medical information without seeking patient consent will have to ensure that certain additional procedures, such as safeguarding the confidentiality of human samples and destroying identifiers that could be used to trace individuals, are followed.

Using the same samples, the team also traced the evolution of Y. pestis and confirmed that it evolved from a soil bacteria closely related to Yersinia pseudotuberculosis, a bacterium that causes Far East scarletlike fever in humans, and is most often spread through food.

Researchers have used radioimmunotherapy (RIT) to destroy remaining human immunodeficiency virus (HIV)- infected cells in the blood samples of patients treated with antiretroviral therapy, offering the promise of a strategy for curing HIV infection.

With this model, called heuristic training, humans provide direct instructions that are used to pre-classify training samples rather than a set of fixed examples.

The next phase of study involving the newly discovered gene mutations will investigate their function using human blood samples at the molecular level.

The scientist tested their set - up using frozen human skin cells, segments of pig heart tissue, and sections of pig arteries in volumes almost 20 times larger than previously attempted samples.

The material Professor Barber tested was almost 100 times thinner than the diameter of a human hair so the techniques used to break such a sample have only just been developed.

They have the opportunity to be exposed to a wide variety of clinical and patient - oriented research, from Phase I, II, and III trials to collection of samples and clinical data used to identify genetic variation that leads to human disease.

Evolutionary geneticists Svante Pääbo, Johannes Krause, and colleagues at the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany, ground up a 30 - milligram sample and extracted and sequenced all of the 16,569 base pairs of its mtDNA genome, using new techniques Pääbo's group has successfully employed to sequence both Neandertal and prehistoric modern human DNA.

When human DNA profiles are used as evidence, it is usual to put numbers to the chance that a semen sample could have come from someone other than the accused.

Dr. Charlier argues that human remains in museums and scientific institutions can be divided into four categories, «ethnographical elements» such as hair samples with no certain identification; anatomical remains such as whole skeletons or skulls; archaeological remains; and more modern collections of skulls, used in now discredited studies in the early 20th century.

The team used this ratio as a benchmark to identify and compare levels of mercury pollution caused by human activities across water samples from different oceans.

One uses primary hepatocytes obtained from livers donated for transplant; the second uses stem cells derived from human skin samples and guided into hepatocyte - like cells, Bhatia says.

Using radiocarbon dating techniques on samples that included human bone, they dated the flood to 1920 BC.

Malamud's microfluidic machine uses four microscopic channels to simultaneously scan a sample: The first looks for human antibodies to the infectious agent, the second for an antigen on the surface of the pathogen, and the third and fourth amplify viral RNA or bacterial DNA.

The team is hopeful that similar bioprosthetic ovaries can be implanted in human patients to restore fertility, using a patient's own previously extracted follicles or donated samples.

They then conducted biochemical analyses to identify neuroligin - 3, confirm that the protein could stimulate tumor growth in cultured samples of several kinds of human high - grade gliomas and study which signals the protein uses within glioma cells to promote their growth.

Using all the existing data that was available, Andrechek, along with MSU doctoral student Daniel Hollern, analyzed 1,172 mouse mammary tumor samples from 26 different preclinical models and was able to compile one of the largest databases to show which strains of mice were best suited to study a particular type of human breast cancer.

Sood and colleagues looked at samples from 80 cases of human ovarian cancer grouped according to patient stress using the National Institutes of Health's Center for Epidemiological Studies Depression scale as a surrogate marker.

Using postmortem human brain samples, the researchers found that variations in the number of copies of the C4 gene that people had, and the length of their gene, could predict how active the gene was in the brain.

Researchers in Mathies's group, working with George Sensabaugh, a forensics expert at Berkeley, have shown that the miniaturised process can be used to type DNA from human blood samples.

The use of muscle tissue in post-mortem studies is a novel approach which presents several advantages: first, muscle tissue is the most abundant tissue of the human body and can therefore be sampled easily.

HDNetDB allows users to obtain, visualise and prioritise molecular interaction networks using Huntington's disease - related gene expression and other types of data obtained from human samples and other sources.

Collaborators at Human Longevity, Inc. sequenced the microbial genes extracted from each participant's stool sample and used that information to determine which species were living where, and the relative abundance of each.

Using human subcutaneous and abdominal fat samples, the scientists, in cooperation with the University Hospital Leipzig and the Karolinska Institutet Stockholm (Sweden), find similar cahnges not only to rodents but also to the human organism.

To detect NAFLD earlier and more easily, researchers in the NAFLD Research Center at University of California San Diego School of Medicine, Human Longevity, Inc. and the J. Craig Venter Institute report that the unique microbial makeup of a patient's stool sample — or gut microbiome — can be used to predict advanced NAFLD with 88 to 94 percent accuracy.

Using human pancreatic samples and mouse models, the HSPH researchers — with colleagues from Harvard Medical School, the Broad Institute of Harvard and MIT, and the Université Libre de Bruxelles — sought to tease apart the mechanisms of beta cell failure in T1D.