Sentences with phrase «using medicinal chemistry»
Cosford had been investigating ULK1 using medicinal chemistry and chemical biology, and had identified some promising lead compounds using rational design.
https://www.salk.edu/ Not exact matches
Sylvie Garneau - Tsodikova's research aims to understand and combat bacterial and fungal resistance by using tools from medicinal chemistry, biochemistry, microbiology, and structural biology.
«Modifications of the treatment regimens, additional optimization of the delivery methods via the use of hydrogels, and structural modifications of the compounds via medicinal chemistry could ensure even better results with CDK2 inhibitors in treating hearing loss in humans.»
«For 20 years we have been using rational bioengineering to modify the chemical structures of clinically important natural products — using genetics to make a new molecule in a process that parallels medicinal chemistry — and that's what we were doing when we stumbled upon this,» said Professor Barrie Wilkinson from the John Innes Centre.
The use of halogen atoms is a promising approach for compound optimization in medicinal chemistry.
«All these are commonly used in medicinal chemistry either as final drug compounds or intermediate compounds from which the final compounds are made,» Yu said.
You should have a passion for medicinal chemistry and enjoy and excel at making molecules using modern methods of organic synthesis.
Promising compounds are being generated using established high throughput screening by medicinal chemistry and are being tested in preclinical animal models.
Our projects are based on chemical biology (use of chemical molecules for understanding biological phenomena) and medicinal chemistry (compounds with therapeutic properties).
Hits identified from a first iteration screen can be fed into a medicinal chemistry program or converted into new baits (Bait B, center left in Figure) and used in a second iteration screen to identify more potent molecules.