Using the nanodiscs, the team elucidated the activation mechanism of receptor kinase AgrC and discovered a key regulatory hotspot in the kinase that could greatly affect its activity.
Not exact matches
They
used cryo - EM analysis to decipher the engineered ATP synthase, which was synthesized in yeast and reconstituted into
nanodiscs to allow for structural analysis.
Next, Hafenstein's group plans to
use a larger
nanodisc to capture the process of the virus interacting with the mock membrane.