Sentences with phrase «using nanoparticle delivery»
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The method involves tagging a molecular drug delivery vehicle with synthetic DNA that can then be used to see how cancerous tumors are responding to specific treatments (the drugs themselves are placed into these tagged nanoparticles).
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Phase I funding — which allows up to $ 250,000 for an academic idea, such as decoding the genetic sequence of a protein or studying targeted drug delivery by using magnetic nanoparticles — is available from federal funding and foundations.
«We envision that these photo - responsive polymer - capped gold nanoparticles could one day serve as nano - carriers for drug delivery into the body using our robust and reversible process for assembly and disassembly,» said Zhiqun Lin, a professor in the Georgia Tech School of Materials Science and Engineering.
«The ability to identify useful drug delivery nanoparticles using this miniaturized system holds great potential for accelerating our discovery process,» Anderson says.
The technique can be applied in myriad ways, some of which include droplet - based microreactors (devices used in chemical synthesis), nanoparticle synthesis, tissue engineering, drug discovery and drug delivery monitoring.
Magnet - directed nanoparticles have previously been used for targeted delivery of chemotherapy drugs.
Khizroev used the tail - to - head trick to spread the nanoparticles through the brain and mimic IV drug delivery in humans.
«We then evaluated the system in rats with glioma and found that by using a method called intracranial convection - enhanced delivery, our nanoparticles could penetrate completely throughout the tumor following a single injection,» says Jordan Green, Ph.D, associate professor of biomedical engineering and ophthalmology at Johns Hopkins.
Using nanoparticles designed and screened for endothelial delivery of short strands of RNA called siRNA, the researchers were able to target RNAi to endothelial cells, which form the linings of most organs.
His research group will also work on targeted delivery of the drug using their patent pending «nanobowls,» which are magnetically guided nanoparticles that can be packed with drugs and diagnostic molecules, deliver them to particular sites in the body and release them on demand.
While on one hand, there is significant potential in the application of nanoparticles in enhancing heat transfer for tumor ablation and targeted drug delivery, there is also much promise in improving imaging and diagnostic protocols using them.
«Breakthrough antimalarial drug delivery system using mesoporous silica nanoparticles.»
One of the hopes is that once nanotechnology is proved safe and effective as a drug delivery system, highly concentrated nanoparticles carrying drugs could be injected directly into the body where they are needed most and use their shape to get to work quickly.
Using chloroquine, the researchers not only increased the circulation of nanoparticles in the body, but also reduced the body's filtration of nanoparticles, as well as improved drug delivery to breast tumors.
«Age - old malaria treatment found to improve nanoparticle delivery to tumors: Nanomedicine researchers find new use for 70 - year - old drug.»
The growing trend to use other types of nanoparticles has revolutionized the food industry by enhancing flavors, improving supplement delivery, keeping food fresh longer and brightening the colors of food.
«Furthermore, the use of particles to create these microswimmers will synergize well with other micro - and nanoparticle based technologies such as nanoparticle drug delivery systems.»
The HZI will develop a vaccination protocol for mucosal administration based on three novel strategies: (i) development and optimization of a vaccination protocol in which parenterally - primed T and B cells are subsequently pulled into the mucosa by the local delivery of the cognate antigen to the requested effector site, (ii) testing the co-administration of antigens with novel mucosal adjuvants using different mucosal immunisation routes and schedules, and (iii) testing various nanoparticles co-administered with different immunomodulators for their ability to generate both systemic and mucosal immune responses following transcutaneous / trans - follicular vaccination.
Nanoparticles for the sole use of imaging agents have a much lower return on investment and higher safety requirements than drug delivery systems... -LSB-...]
Nanoparticles conjugated with two active ligands, one for its effective uptake and the other for it's binding or use to gene delivery agents to deliver drug inside cells.
Because of their unique properties such as monodispersity, large surface area and high drug loading efficiency, silica nanoparticles (SiNPs) have been developed for a vast array of biomedical uses such as optical imaging, cancer therapy, targeted drug delivery and controlled drug release for genes and proteins.
Using nanoparticles, Yale researchers have developed a drug - delivery system that could reduce organ transplant complications by hiding the donated tissue from the recipient's immune system....
The award will support graduate students working on the project, and also help offset other costs, such as producing sufficient quantities of the compound analogs, optimization of the nanoparticle delivery system, and the cost of the mice used to model leukemia.
A new method, which makes use of innovative nanoparticles, could change that, providing a less harmful «cluster bomb» approach to delivery.
«The question now is, can the nanoparticles be effective delivery vehicles for vaccines or be used for for co-delivery of antigens and adjuvants?
But administering curcumin using a different pharmaceutical delivery system, solid lipid nanoparticles (SLN), improves its stability and lengthens its time of release, resulting in better skin penetration.