Sentences with phrase «using new gene»

The research was done in brewer's yeast, but it can potentially be applied in insects, aquatic organisms and plants using a new gene editing technique known as CRISPR - Cas9.

Using the new gene - editing enzyme CRISPR - Cpf1, researchers at UT Southwestern Medical Center have successfully corrected Duchenne muscular dystrophy in human cells and mice in the lab.

«Neuroscientists are using these new gene - editing and molecular tools to develop potential therapeutic targets across multiple disease fronts.»

Using new gene editing techniques like CRISPR / Cas9 to treat genetic diseases is fine under certain conditions, but it should not be used to enhance people, a panel of experts says.

UT Southwestern Medical Center researchers successfully used a new gene editing method to correct a mutation that leads to Duchenne muscular dystrophy (DMD) in a mouse model of the condition.

A Yale - led research team used a new gene editing strategy to correct mutations that cause thalassemia, a form of anemia.

Researchers have used a new gene - hunting technique to pinpoint a novel genetic variant that raises some people's odds of having a heart attack.

Not exact matches

That's not to say gene editing is new (it isn't), but Crispr simplifies the process by using molecular scissors that can be precisely targeted to snip out aberrant regions of genetic code, which can then be replaced with the correct sequences.

The team gene - edited yeast to create a new strain not so different from the yeast used to brew beer — except, instead of producing alcohol, this one eats sugar and spits out collagen.

The statement on Thursday comes amid a growing debate over the use of powerful new gene editing tools in human eggs, sperm and embryos, which have the power to change the DNA of unborn children.

Using the gene - editing tool CRISPR - Cas9 to turn off certain genes in a mouse zygote as well as other new techniques to enrich the pluripotent stem cells of a rat, the group managed to grow various rat organs (a pancreas, heart, and eyes) in a mouse embryo.

Well, one startup is seeking to take a very different approach: Exonics Therapeutics, which has secured $ 5 million in seed funding from CureDuchenne Ventures to see if the revolutionary new CRISPR - Cas - 9 gene - editing technology can be used to target the root genetic deficiency at the heart of the disease.

So far, its trials have shown it can improve outcomes when used alongside other multiple myeloma drugs and that could offer it some insulation if the market gets disrupted by new treatment approaches, such as gene therapy.

By invalidating key parts of Myriad's patents, the court has removed a bar that prevented labs using new technology from developing and selling broader one - time tests that search for all known cancer risks, including the BRCA genes, geneticists said.

«Using a new approach of combining molecular identification of the SPIKE gene and conventional breeding, we have developed rice, with the SPIKE gene, that has higher yield when compared with an equivalent rice without the gene,» Dr. Kobayashi said.

Before the products from these varieties can be used, they will need approval from the Office of the Gene Technology Regulator, which ensures GM plants are safe for humans and the environment and from Food Standards Australia and New Zealand which regulates food safety.

The EC has historically supported IRRI's work to conserve the genetic diversity of rice, understand the function of rice genes, and develop new rice varieties, particularly for use in difficult growing environments.

Beyond this, the unique power of GM lies in its ability to incorporate novel genes with useful traits for rice, including genes from plants and organisms unrelated to rice, into new rice varieties that can not be achieved using other breeding methods.

Once specific genes associated with beneficial traits are identified, they can be more efficiently transferred into new rice varieties using other breeding methods.

In 2012, at the Central Institute for Cotton Research in Nagpur, I saw a new variety of GM cotton carrying two so - called «stacked» Bt genes in one test plot, while a nearby plot was testing a variety of cotton using organic methods — for some farmers the premium prices for organic cotton make it worthwhile.

The newer process of genetic engineering, which involves inserting genes from unrelated species into a plant's genome to add desirable traits, has been used in crops such as corn, soy, and potatoes.

The recent Lancet Breastfeeding Series refers to new discoveries being made about breastmilk — such as its role in gene expression — so it can be expected that Nestle will use the strategy of launching «new improved» formulas that are «closer to breastmilk» for decades to come (Nestle is currently investing heavily in epigentics research).

A new study in Biological Psychiatry found that heroin use is associated with excessive histone acetylation, an epigenetic process that regulates gene expression.

In the new research, which was conducted in collaboration with Duke - NUS Medical School in Singapore, scientists used computational techniques to scan thousands of genes and mutations associated with epilepsy.

The scientists used CRISPR, a gene - editing tool, to alter inserted genes so that the enzymes for which they coded would work most efficiently amid the exotic acidity, osmotic character and chemical composition of their new home.

Lacking money to outfit the new lab, Wang and Xin bought used equipment: a single channel DNA sequencer (bought and barely touched by a Harvard Medical School researcher); second - hand centrifuges and pipettes; a reconditioned CytoScan HD system that detects variations in the number of copies of a gene.

In the new research, the UB scientists found they could reverse those social deficits with a very low dose of romidepsin, which, they found, restores gene expression and function using an epigenetic mechanism, where gene changes are caused by influences other than DNA sequences.

A genetics research team at Johns Hopkins Medicine has solved a dilemma facing researchers who use genomewide association studies (GWAS) by developing a new approach that strategically «filters» which genes are worth further study.

Immune reactions against proteins commonly used as molecular scissors might make CRISPR / Cas9 gene editing ineffective in people, a new study suggests.

New research at the University at Buffalo reveals the first evidence that it may be possible to use a single compound to alleviate the behavioral symptoms by targeting sets of genes involved in the disease.

In the new study, Duke University researchers overcame several of these obstacles by using a non-pathogenic carrier called adeno - associated virus, or AAV, to deliver the gene - editing system.

Making a new gene, for example, used to involve months of toil and creativity.

Using this process, scientists can make targeted mutations in the genomes of living animals, either deleting genes or inserting new ones.

Using a modified version of the CRISPR genome - editing system, MIT researchers have developed a new way to screen for genes that protect against specific diseases.

Biologists could use an infusion of mathematics as well, says Iya Khalil, vice president of R&D at Gene Network Sciences Inc. in Ithaca, New York.

These strands, known as oligonucleotides, take only a day or two to prepare and can be used to create custom genes to give cells new functions.

«Our study validates using fruit flies as a model to discover new genes that may also control aggression in humans.»

McCaffrey and his colleagues were trying to shut down the activity of a gene in living mice, using a completely new type of drug.

The researchers say this finding may indicate that cells use one strand to keep genes intact and the other to evolve new, potentially advantageous features.

Using a new technique to deliver gene - therapy - like intervention directly where it's needed, researchers at Thomas Jefferson University successfully increased or decreased the muscle tone of the anal sphincter in appropriate animal models.

In a new study published in The Quarterly Review of Biology, Dr. Karen Hardy and her team bring together archaeological, anthropological, genetic, physiological and anatomical data to argue that carbohydrate consumption, particularly in the form of starch, was critical for the accelerated expansion of the human brain over the last million years, and coevolved both with copy number variation of the salivary amylase genes and controlled fire use for cooking.

The new and improved wheat assembly will help wheat breeders accelerate their crop improvement programmes and researchers to discover genes for key traits such as yield, nutrient use and bread making quality.

Last year, using this technique, the team identified eight new relationships between genes and diseases.

In this month's issue of Genome Research, Elizabeth Stewart and her colleagues at Stanford University present this new map, which places about 8000 landmarks along the genome's 3 billion bases — DNA's building blocks — yielding twice the resolution of gene maps currently in use.

Inheriting a single X chromosome exposes men to a host of X-linked diseases, such as hemophilia or Duchenne muscular dystrophy, and researchers hope to use the new data to understand more fully the role of genes in other X-linked conditions.

In 1993, between the first and second years of his MBA program, Kreiner interned at Affymetrix, a then - new company that used technology from the semiconductor industry to analyze vast numbers of genes.

Using the new data, Laura Carrel, a geneticist at Pennsylvania State College of Medicine in Hershey, and Huntington Willard, a geneticist at Duke University in Durham, North Carolina, discovered that 15 percent of the genes on the inactivated X chromosome are actually not silenced — and most are likely to be expressed at higher levels overall in women than men.

A team of researchers at the University of Central Florida is using breakthrough gene - editing technology to develop a new screening tool for Parkinson's disease, a debilitating degenerative disorder of the nervous system.

In the current work, they used a new variation of the gene - editing system to repair the defect in both a mouse model and in human cells.

They have also used state - of - the - art information about brain development to accurately pinpoint new genes and biological pathways implicated in this disorder.