For the first time, researchers have the ability to analyse malaria genomes straight from patient blood samples
using new sequencing technologies and informatics methods.
I've also
used new sequencing technologies to zoom in on how flu evolves in individual people while they're sick.
Color - Pickers, RTE's, etc in the «global» Controls will be initialized first
using the new sequenced initialization queue.
Not exact matches
That's not to say gene editing is
new (it isn't), but Crispr simplifies the process by
using molecular scissors that can be precisely targeted to snip out aberrant regions of genetic code, which can then be replaced with the correct
sequences.
Beim was touring lab space in
New York, aghast at how expensive it was, when she realized she didn't actually need her own lab — she could outsource the genetic
sequencing and
use Amazon Web Services as her server farm.
This blockchain manager would «compute a cryptographic hash» of a given «nucleic acid
sequence» and «
use» it as PoW before transmitting the attendant «
new block... to the other nodes in [the] blockchain system.»
But it may be pointed out that (1) no one has ever «unstrung» the Marcan
sequence more completely than the author of Matthew did in revising and reorganizing the Gospel of Mark for his special purposes: the book is taken apart and put together again in a
new order, combined with the «Sayings Source» (Q) and with other materials, and arranged apparently for didactic
use — as a manual, one might say, for the religious educators of the early Syrian church!
Use the email initiation
sequence to start a relationship off on a good foot, sending
new list members a pre-set series of messages after they sign up.
Using a relatively
new technology called CRISPR / Cas9, they managed to accurately cut out specific DNA
sequences from leukemia cells.
In the
new research, the UB scientists found they could reverse those social deficits with a very low dose of romidepsin, which, they found, restores gene expression and function
using an epigenetic mechanism, where gene changes are caused by influences other than DNA
sequences.
«Genomic
sequencing used to help identify
new therapies for bile duct cancer.»
This
new sequencing approach can be
used for any DNA that is too fragmented to be read well through more traditional methods.
«We explored the opportunity of
using sperm RNA elements as a predictor of human health, with applications at the fertility clinic that would go hand - in - hand with the
new neonatal intensive care unit genome
sequencing to better health outcomes,» said Dr. Krawetz, associate director of the C.S. Mott Center for Human Growth and Development.
The
new study, led by Johannes Krause, a geneticist at the Max Planck Institute for the Science of Human History in Jena, Germany,
used next - generation
sequencing methods to read stretches of any DNA present in a sample and fish out those that resembled human DNA.
We
used massively parallel viral
sequencing to understand how and when EBOV entered human populations in the 2014 West African outbreak, whether the outbreak is continuing to be fed by
new transmissions from its natural reservoir, and how the virus changed, both before and after its recent jump to humans.
For this purpose, the scientists combined a sophisticated bioinformatics strategy developed by Masaomi Hatakeyama that
uses state - of - the - art
sequencing methods with a
new technology that can optically map the long, individual DNA molecules in the genome.
Reporting in today's issue of Science, Gershenfeld and colleagues describe how they designed the
new technology
using the presence or absence of a
sequence of bubbles as a substitute for the conventional «on» or «off» binary language of computer circuits.
Molecular clocks
use the rate at which DNA
sequences change to estimate how long ago
new species arose, assuming a relatively steady rate of genetic evolution.
«
Using a combination of physical characteristics and DNA
sequence data, I was able to determine that it was a species
new to science.»
To
sequence the enormous genomes, researchers
used powerful sequencers and
new sequence - analyzing software.
Using next - generation
sequencing technologies that were previously unavailable, Michael Gardner, a graduate research assistant, and Jianying Wang, a senior research associate in Mitchum's lab, made a remarkable
new discovery — nematodes possess the ability to produce a second type of peptide that can effectively «take over» plant stem cells that are
used to create vital pathways for the delivery of nutrients throughout the plant.
«However, our
new approach
uses cutting - edge DNA
sequencing technology to precisely measure the effects of thousands of
sequences on gene activity at the same time.»
A
new, less expensive, and faster method now has been developed and
used to determine the DNA
sequence of the male - specific Y chromosome in the gorilla.
Described in the January 7th issue of Neuron, the technique
uses «deep,» highly sensitive whole - genome
sequencing of single neurons and a
new technology that identifies inserted bits of DNA caused by retrotransposons, one of several kinds of so - called somatic mutations that can arise as the brain develops.
GenePeeks, based in
New York,
sequences the prospective parents» DNA and
uses this to create thousands of different virtual embryos.
The
new research focused on just nine genes, those most strongly associated with autism in recent
sequencing studies, and investigated their effects
using precise maps of gene expression during human brain development.
Reported in Nature Methods today, the
new open source computer tool called Single Cell Consensus Clustering (SC3) was shown to be more accurate and robust than existing methods of analysing single - cell RNA
sequence data, and is freely available for researchers to
use.
To demonstrate
use of the
new nomenclature, the authors of the study review recently published news species descriptions in the ichthyological literature that include DNA data and apply the GenSeq nomenclature to
sequences referenced in those publications.
This
new method sidesteps both of those restrictions and allows the
use of two
sequences that are only weakly random.
Evolutionary geneticists Svante Pääbo, Johannes Krause, and colleagues at the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany, ground up a 30 - milligram sample and extracted and
sequenced all of the 16,569 base pairs of its mtDNA genome,
using new techniques Pääbo's group has successfully employed to
sequence both Neandertal and prehistoric modern human DNA.
«The findings need to be confirmed
using targeted RNA
sequencing, or internal validation, and then tested in a
new cohort of patients, or external validation.
The team employed a
new, massively parallel technique called pyrosequencing, which
uses pulses of light to read the
sequence of thousands of bases at once.
Over the next year, the company plans to
use data from human genomes
sequenced with its
new machines to develop the statistics needed to evaluate how accurate the data are.
To trace the source of the anthrax, the FBI
used «microbial forensics,» a
new approach that combines established microbiology techniques with DNA
sequencing.
Using existing low - cost and low - weight technology in
new ways, the team created a modular «life detection platform» able to culture microorganisms from soil samples, assess microbial activity, and
sequence DNA and RNA.
In the meantime, Boeke says Sleeping Beauty could provide a
new and better way to create mutants to study embryonic development, since the inactivated gene can be «tagged»
using a short DNA
sequence inserted by the transposon.
The Swedish drug company Astra AB, which wanted to
use the DNA
sequence to design
new antimicrobial agents, bought the rights to that single genome for $ 22 million.
Researchers in the Baker lab and around the world are increasingly
using Rosetta to design
new protein structures and
sequences aimed at solving real - world problems.
Dr Ewan Birney, Senior Scientist and Director of EMBL - EBI,
used new computational techniques to analyse the
sequence of genetic information held in each of the sample genomes.
Researchers investigated the glycophorin area of the genome in more detail than before
using new whole - genome
sequence data from 765 volunteers in the Gambia, Burkina Faso, Cameroon and Tanzania.
To overcome the extreme genomic complexity, the team
used new long - read
sequencing technology that boosted the quality of the genome
sequence obtained by more than one hundred fold over standard short - read approaches.
Using Project 2061's Atlas of Science Literacy and other tools, workshop participants get a better understanding of the science ideas students need to learn and develop
new strategies for
sequencing lessons to build on what students already know and for helping students see how concepts fit together and can be applied to various scenarios.
The team
used a
new approach to gene
sequencing that enabled them to completely reconstruct the virus» previously unknown genome in less than 24 hours — significantly faster than conventional
sequencing techniques, which can take days to weeks.
Researchers from Sanford Health and Chronix Biomedical today announced that results from a pilot study demonstrating the utility of a
new cancer panel to detect previously undetected viral and cancer mutations are to be reported in a poster presentation titled «Detection of novel HPV mutations and chromosomal number imbalance (CNI) in oropharyngeal and laryngeal cancer
using next - generation
sequencing (NGS)» at the American Society of Clinical Oncology Annual Meeting (ASCO 2014) being held from May 30 through June 3, 2014 in Chicago.
«
Sequencing of barley genome achieves
new milestone: Researchers improves a resource
used worldwide.»
The key to the solution was
using a
new method to pre-process the gargantuan pile of
sequence data so that it could all fit within the working memory of a single super-computer.
«We have also
used a
newer method called Illumina
sequencing.
The
use of next - generation gene
sequencing in newborns in neonatal intensive care units (NICUs) may improve the diagnosis of rare diseases and deliver results more quickly to anxious families, according to
new research in CMAJ (Canadian Medical Association Journal).
Now,
using new data collected samples of ancient, carbonized rice, a team of Japanese and Chinese scientists have successfully determined DNA
sequences to make the first comparisons between modern and ancient rice.
Using «homologous recombination,» CRISPR can also be
used to insert
new DNA
sequences or even whole genes into the genome in a precise way.