Sentences with phrase «using newer tumor»

Rose is currently awaiting results from a new round of mice in development using newer tumor cells.

Not exact matches

Chicago, GenomeWeb — A new study by researchers from Memorial Sloan Kettering Cancer Center has demonstrated the predictive power of an AR - V7 protein expression test using Epic Sciences» non-EPCAM-based circulating tumor cell detection platform, which could help guide treatment decisions for men with metastatic castration - resistant prostate cancer.

Unlike conventional chemotherapies and radiation that indiscriminately eradicate fast - growing tissues and ravage people's bodies with side effects, new therapies specifically target tumors using tailored cells from individual patients.

«Researchers are using newer technologies to look directly into tumors,» she says, «to make sure immunotherapies induce a response that works in the tumor.»

They discovered that the chemicals and radiation used to kill tumor cells damage the stem cell reservoir in the hippocampus and nearly halt the formation of new neurons in both children and adults.

In a paper published in the May 5 online issue of The Oncologist, researchers at the University of California, San Diego School of Medicine and Moores Cancer Center detail their experience evaluating 34 patients between December 2012 and June 2013 using a molecular tumor board — a new type of advisory group comprised of multidisciplinary experts, including those in the fields of tumor genetics, basic science and bioinformatics.

For some years now, a new class of drugs called antibody - drug conjugates (ADCs) have been used, which work in two ways: they consist of an antibody that binds selectively to the tumor cell receptor and interrupts the signal to propagate; they also act as a transport vehicle for a chemical substance that enters the cancer cells with the antibody and triggers their death.

Another possible application for the new machine is generating peptides that could be used as personalized cancer vaccines targeting unique proteins found in individual patients» tumors.

In this new study published in Nature, Alexandra Van Keymeulen and colleagues used state of the art genetic mouse models to identify the cellular origin of PIK3CA and p53 induced breast tumors.

That's because hospitals are equipped with powerful new scanning machines primarily used to identify tumors, ballooning blood vessels, bone fractures, and a wide range of disorders in people.

Finding new treatments is critical because less than 5 percent of patients with pancreatic neuroendocrine tumors respond to everolimus, the most commonly used pharmaceutical, François said.

Interphone compared surveyed cell phone use in 6,420 people with brain tumors to that of 7,658 healthy people in 13 developed countries — Australia, Canada, Denmark, Finland, France, Germany, Israel, Italy, Japan, New Zealand, Norway, Sweden and the U.K. — to try to determine whether people with brain tumors had used their cell phones more than healthy people, an association that might suggest that cell phones caused the tumors.

The initial experiments made use of cancer cells that Quiñones - Hinojosa and his team removed from willing patients and grew in the laboratory until they formed little spheres of cells, termed oncospheres, likely to be the most resistant to chemotherapy and radiation, and capable of creating new tumors.

Scientists at Barrow Neurological Institute have recently made discoveries about use of a new technology for imaging brain tumors in the operating room — a finding that could have important implications for identifying and locating invading cells at the edge of a brain tumor.

His research largely focuses on new means to incorporate imaging methods to view cells of brain tumors with a hand held instrument that a neurosurgeon can use to visualize the individual cells during the progress of the operation.

The new test uses a highly sensitive gene mutation detection method that is based on the partitioning of DNA into droplets to detect specific circulating tumor DNA mutations and RNA variants in whole blood.

To overcome these problems, Min and his team developed a new modality to visualize glucose uptake activity inside single cells based on stimulated Raman scattering (SRS) imaging, and demonstrated its use in live cancer cells, tumor xenograft tissues, primary neurons and mouse brain tissues.

In the new studies, three independent groups used genetic cell - marking techniques to trace the proliferation of certain cells within growing tumors.

In the past few years, Vogelstein and Kinzler have shifted away from discovering new cancer genes to a less glamorous pursuit: using genetic tests to detect common tumors as early as possible, when they are easiest to cure.

In the first test using KnIT, the team sought to identify new protein kinases that phosphorylate (or turn on) the protein tumor suppressor p53.

In a new International Journal of Cancer analysis, researchers found a link between maternal residential pesticide use — particularly insecticides — and the risk of childhood brain tumors.

Researchers at The Rockefeller University have shown that a new technique using RNA interference is able to find genes that cause epidermal tumor growth in months rather than the decades it may take using traditional methods employing specially bred, genetically altered mice.

«New technology can detect tiny ovarian tumors: «Synthetic biomarkers» could be used to diagnose ovarian cancer months earlier than now possible.»

In the new study, the researchers used a combination of four different therapies to activate both of the immune system's two branches, producing a coordinated attack that led to the complete disappearance of large, aggressive tumors in mice.

CellSearch is used primarily to check the progress of cancer treatment, whereas U.C.L.A.'s imaging technology could find cancerous cells at an earlier stage, before they can form a new tumor.

To find tumors via MRI, the Stanford team used a new contrast agent consisting of nanoparticles of iron.

In the new paper, the researchers used CRISPR to introduce cancer - causing mutations into the organoids and then delivered them via colonoscopy to the colon, where they attached to the lining and formed tumors.

It also may have helped several others by boosting the power of a new type of cancer drug that uses a different mechanism to unleash an immune attack on the tumor.

Using their new model, the researchers found that certain parameters about the way a tumor grows could successfully and accurately predict its response to anti-angiogenic treatment that targets VEGF activity.

In several steps using a new strategy and a novel drug, Burkhard Becher's team from the Institute of Experimental Immunology at the University of Zurich has now succeeded in doing exactly this in the case of glioblastoma, one of the most dangerous brain tumors.

A new study led by scientists at The Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James) suggests that dopamine — an inexpensive drug currently used to treat heart, vascular and kidney disorders — can be safely used in cancer treatment to curb the growth of blood vessels in tumors.

«Age - old malaria treatment found to improve nanoparticle delivery to tumors: Nanomedicine researchers find new use for 70 - year - old drug.»

July 21, 2006 Novel technique used to remove tumor in infant's liver On June 28, infant Chloe Lobins received a liver resection — removal of part of the organ — and a new chance at life at the University of Chicago Comer Children's Hospital.

The safe use of a stem - cell - based therapy against brain metastasis would require preventing the engineered cells from persisting within the brain, where they could affect normal tissue and possibly give rise to new tumors.

At a time when gene therapy has been revived as a potent form of cancer treatment, a new approach would use nanoparticles, rather than viruses, to deliver strands of DNA or RNA to tumors.

In a 1988 paper summarizing his findings, Fiebig concluded that xenograft mice were wonderful models for broadly testing new drugs against human tumors, but they «can not be used as a clinical routine method» for predicting patient treatment.1 The idea of using xenograft mice as personal avatars for cancer patients was discarded.

Now, patients with pancreatic cancer desperate for new treatment options will potentially benefit from a powerful new technology that uses genetic engineering to turn their own immune cells into «specially trained assassins» capable of finding, attacking, and eliminating pancreatic cancer tumors.

School of Allied Health Sciences» Steen Madsen is exploring new treatment methods for primary brain tumors — tumors that originate in the brain — using nanoparticles and lasers.

We need a new type of vaccine that uses select components of a microbe or tumor cell or other cause of disease, and administers these with other defined substances, such as adjuvants, that directly exploit immunology.»

Magnus Essand and Justyna Leja at SciLifeLab / Uppsala University has together with their colleagues developed a new treatment for tumors, using viruses.

Using new technologies to analyze thousands of genes and proteins simultaneously from tumors, Dr. Chak hopes to identify molecular patterns that will predict an individual's response to specific agents.

$ 1.8 M Supports Cancer Drug Discovery on Commonly Mutated Gene New Brunswick Patch — April 5, 2016 Behavioral Scientist Shares Insights about FDA's Proposed Rule on Banning Tanning Bed Use among Minors News-Medical.net - March 19, 2016 Intervention Program Reduces Caregiver Distress during Hospitalization of Pediatric Stem Cell Transplant Patients News-Medical.net - March 9, 2016 Exploring Genomic Pathways in the Development of Ovarian Cancer GMNews.com - March 2, 2016 Differences in Type of Small Protein may further Elucidate Lung Cancer Risk in African Americans ScienceDaily.com - March 2, 2016 Study Looks at Post-Treatment Resources for Prostate Cancer Patients Transitioning to Survivorship News-Medical.net - February 11, 2016 Drawing the Line on Tanning Bed Use by Teens ScienceDaily.com - December 21, 2015 What Rutgers Study Uncovered about E-Cigarette Use NJBiz.com - December 9, 2015 Identification of Barrier that Prevents Progression of Benign Kidney Tumors to Malignant Disease MedicalNewsToday.com - November, 24, 2015 What is the Color of the Lung Cancer Ribbon?

Now, in a new study in the journal Cancer Cell, Shaw and a team of scientists at the Salk Institute for Biological Studies found that phenformin, a derivative of the widely - used diabetes drug metformin, decreased the size of lung tumors in mice and increased the animals» survival.

New and innovative technology would use radiation beams to target tumors and leave healthy tissue intact.

CXCR4 is a receptor that cancer cells use like antennae to feel their way from their parent tumor to distinct sites in the body where they will establish a new tumor.

Since starting her new role as an investigator in the In Vivo Pharmacology group at Novartis Oncology, Bhang has been working on using the ClonTracer library to monitor clonal dynamics following drug treatment in cell line and primary tumor xenograft models.

Motion model ultrasound localization microscopy (mULM) is a new tool using CEUS to morphologically and functionally characterize fine vascular networks in tumors at super-resolution.

Other research is investigating whether agonist reagents that can signal various immune cells such as T cells, dendritic cells, or NK cells, through the TNF family receptors OX40, 4 - 1BB, HVEM, or LTβR can be used to increase natural immune responses to viruses or tumors that might lead to new strategies for vaccination.

Bryan Choi, the recipient of a Student Training and Research in Tumor Immunology (STaRT) grant at Duke University, is working to develop a new strategy using Bispecific T cell Engagers (BiTEs) to treat glioblastoma.

In addition, new small molecule drugs are being used that target important survival pathways in NHL tumor cells.